DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycJ and Ccnb2

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_031656.2	Gene:	Ccnb2 / 12442	MGIID:	88311	Length:	398	Species:	Mus musculus

Alignment Length:	320	Identity:	81/320 - (25%)
Similarity:	129/320 - (40%)	Gaps:	75/320 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DRKLKKTCPQADVERLAKTHWLTDYARDIFLTMREQEL--SRRPLFYLSPQLNERRR--MLQLLK 75
            ||:..:.|              :||.:||:..:|:.|:  |..|.|.....:|.|.|  ::..|.
Mouse   124 DRENPQLC--------------SDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLV 174

  Fly    76 LATSAHKLSRCALHLAVYYMDRFVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLV 140
            ...|..:|.:..|::.:..||||:....:...||.||.||.|.:|::.|  :.|.|...:...:.
Mouse   175 QVHSKFRLLQETLYMCIAIMDRFLQAQLVCRKKLQLVGITALLLASKYE--EMFSPNIEDFVYIT 237

  Fly   141 KNAYTAFEYKAVERKILCFLNFELIRPTTASFVELFACSFLTRSDFKNYIEMLDEYERNHHTQPY 205
            .||||:.:.:.:|..||..|.|||.||        ....||.|:      ....|.:...||
Mouse   238 DNAYTSSQIREMETLILKELKFELGRP--------LPLHFLRRA------SKAGEVDVEQHT--- 285

  Fly   206 QRYISFEEMLSILAQLL--LRMADYTLYISRFANDLPSLLAAACIAAVRQVSGVRRWSEYLVGLT 268
                        ||:.|  |.:.||.:     .:..||.:|||.....::|.|..:|:......|
Mouse   286 ------------LAKYLMELTLVDYDM-----VHYHPSQVAAAASCLSQKVLGQGKWNLKQQYYT 333

  Fly   269 SYTEANVEPYM-----NVL---TDYYYYHVIQTDYGS---------PSVQTN--QSLASP 309
            .|.|:.|...|     ||:   .:...:..::..|.|         |.:.:.  :.||||
Mouse   334 GYMESEVLEVMQHMAKNVVKVNDNRTKFIAVKNKYASSRLLKISTIPQLNSKIIKDLASP 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	38/125 (30%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044	17/68 (25%)
Ccnb2	NP_031656.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	65..97
		Cyclin_N	137..262	CDD:278560	39/126 (31%)
		Cyclin_C	264..382	CDD:281044	31/151 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820