DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycJ and Ccna2

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_033958.2	Gene:	Ccna2 / 12428	MGIID:	108069	Length:	422	Species:	Mus musculus

Alignment Length:	302	Identity:	78/302 - (25%)
Similarity:	126/302 - (41%)	Gaps:	53/302 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DYARDIFLTMREQELSRRP-LFYLSPQ---LNERRRML-QLLKLATSAHKLSRCALHLAVYYMDR 97
            ||..||...:||.|:..:| :.|:..|   .|..|.:| ..|......:||....|||||.|:||
Mouse   167 DYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDR 231

  Fly    98 FVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLVKNAYTAFEYKAVERKILCFLNF 162
            |:....:...||.||....:.:|::.|  :.:.|..:|...:..:.|:..:...:|..:|..|.|
Mouse   232 FLSSMSVLRGKLQLVGTAAMLLASKFE--EIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAF 294

  Fly   163 ELIRPTTASFVELFACSFLTRSDFKNYIEMLDEYERNHHTQPYQRYISFEEMLSILAQLLLRMAD 227
            :|..||...|:..:   ||                   |.||..  ...|.:...|.:|.|..||
Mouse   295 DLAAPTVNQFLTQY---FL-------------------HLQPAN--CKVESLAMFLGELSLIDAD 335

  Fly   228 -YTLYISRFANDLPSLLAAACI-AAVRQVSGVRRWSEYLVGLTSYTEANVEPYMNVLTDYYYYHV 290
             |..|       ||||:|.|.. .|:..|:| :.|.|.|...|.||..:::|   .|.|.:..::
Mouse   336 PYLKY-------LPSLIAGAAFHLALYTVTG-QSWPESLAQQTGYTLESLKP---CLVDLHQTYL 389

  Fly   291 IQTDYGSPSVQTNQSLASPDSGFEESFTENTNLVVSDEVVTV 332
            ....:...|::..         ::.|...:.:|:...|.::|
Mouse   390 KAPQHAQQSIREK---------YKHSKYHSVSLLNPPETLSV 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	36/126 (29%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044	22/62 (35%)
Ccna2	NP_033958.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62
		Cyclin_N2	22..152	CDD:293109
		Cyclin_N	171..297	CDD:278560	36/127 (28%)
		Cyclin_C	299..417	CDD:281044	37/161 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810