DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycJ and Ccna1

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_001292150.1	Gene:	Ccna1 / 12427	MGIID:	108042	Length:	421	Species:	Mus musculus

Alignment Length:	252	Identity:	67/252 - (26%)
Similarity:	104/252 - (41%)	Gaps:	38/252 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LTDYARDIFLTMREQELSRRP-LFYL--SPQLNERRR--MLQLLKLATSAHKLSRCALHLAVYYM 95
            :|:||.:|...:||.|:..|| ..|:  .|.:.|..|  ::..|......:||....|:|||.::
Mouse   164 VTEYAEEIHRYLREAEVRHRPKAHYMRKQPDITEGMRAILVDWLVEVGEEYKLRTETLYLAVNFL 228

  Fly    96 DRFVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLVKNAYTAFEYKAVERKILCFL 160
            |||:....:...||.||....:.:|::.|  :.:.|...|...:..:.||..:...:|..:|..|
Mouse   229 DRFLSCMSVLRGKLQLVGTAAILLASKYE--EIYPPDVDEFVYITDDTYTKRQLLRMEHLLLKVL 291

  Fly   161 NFELIRPTTASFVELFACSFLTRSDFKNYIEMLDEYERNHHTQPYQRYISFEEMLSILAQLLLRM 225
            .|:|..|||..|                    |.:|.|....     .|..|.:...:|:|.|..
Mouse   292 AFDLTVPTTNQF--------------------LLQYLRRQGV-----CIRTENLAKYVAELSLLE 331

  Fly   226 ADYTLYISRFANDLPSLLAAACIAAVRQVSGVRRWSEYLVGLTSYTEANVEPYMNVL 282
            ||      .|...||||:|||.......:.....|.|.|...|.|:...:.|.::.|
Mouse   332 AD------PFLKYLPSLVAAAAYCLANYIVNRHFWPETLAAFTGYSLNEIVPCLSEL 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	34/126 (27%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044	17/58 (29%)
Ccna1	NP_001292150.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		Cyclin_N2	27..>101	CDD:406812
		CYCLIN_CCNA1_rpt1	132..294	CDD:410263	36/131 (27%)
		CYCLIN_CCNA1_rpt2	298..420	CDD:410266	29/116 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820