DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycJ and Ccnf

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	XP_038941012.1	Gene:	Ccnf / 117524	RGDID:	67401	Length:	818	Species:	Rattus norvegicus

Alignment Length:	341	Identity:	72/341 - (21%)
Similarity:	134/341 - (39%)	Gaps:	65/341 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LTMREQELSRRPLFYLSPQLNERRRML---QLLKLATSAHKLSRCALHLAVYYMDRFVDYYKIRP 106
            |....|.::::.:|.:...|::..|.:   .|:::||.....|.| |||.|..:||::....:..
  Rat   324 LFQASQAVNKQQIFSVQKGLSDTMRYILIDWLVEVATMKDFTSLC-LHLTVECVDRYLRRRLVPR 387

  Fly   107 DKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLVKNAYTAFEYKAVERKILCFLNFELIRPTTAS 171
            .||.|:.|.|:.|..:..:.:....|  |...|..|.|...:...|..:|:..|..::..||...
  Rat   388 YKLQLLGIACMVICTRFISKEILTIR--EAVWLTDNTYKYEDLVRVMGEIISALEGKIRIPTVVD 450

  Fly   172 FVELFACSFLTRSDFKNYIEMLDEYERNHHTQPYQRYISFEEMLSILAQLLLRMADYTLYISRFA 236
            :.|:.             :.::....|..|            :.|.|.:|.|.....::|
  Rat   451 YKEVL-------------LTLVPVAPRTQH------------LCSFLCELTLLHTSLSVY----- 485

  Fly   237 NDLPSLLAAACIAAVRQVSG-VRRWSEYLVGLTSYTEANVEPYMNVLTDYYYYHVIQTDYGSPSV 300
              .|:.||:|.:...|.:.| .:.|:..|..||.::.:::.|.:..|....::.....||
  Rat   486 --APARLASAALLLARLMHGHTQPWTTQLWDLTGFSYSDLTPCVLSLHKKCFHDDAPKDY----- 543

  Fly   301 QTNQSLASPDSGFEESFTENTNLVVSDEVVT-VETYNIITVQLQDPSPHS-------STFLP--- 354
             ...||.:....||:...|.   :..:||:: .|..:.:.|:.:.|.|.|       .|||.
  Rat   544 -RQVSLTAVKQRFEDKCYEE---ISQEEVLSYAELCSALGVKQESPEPPSFPSSGEIHTFLSSPS 604

  Fly   355 ------KEQTNLKRSR 364
                  |.:.:|:..|
  Rat   605 GRRSKRKRENSLQEDR 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	30/121 (25%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044	13/61 (21%)
Ccnf	XP_038941012.1	FBOX	73..111	CDD:197608
		CYCLIN_CCNF_rpt1	345..439	CDD:410225	25/96 (26%)
		CYCLIN_CCNF_rpt2	467..578	CDD:410226	28/138 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900