Protein Alignment armi and DNA2

DIOPT Version :9

• Sequence 1: NP_001014556.1
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_012034.1
• Gene: DNA2 / 856569
• SGDID: S000001207
• Length: 1522
• Species: Saccharomyces cerevisiae
• Alignment Length: 1350
• Identity: 258/1350 - (19%)
• Similarity: 475/1350 - (35%)
• Gaps: 414/1350 - (30%)

  Fly     8 FFTN-PDRNREDIL--ESLDRENS--FLDQKLMEEKMDQQLKANPNEINGVLSNKIAELTHGLSE 67
            |:.| .|.|.:.|.  |.::..:|  |.|..|:|...:.|.:..||.|...| :|:.::..  .:
Yeast   333 FYENEEDSNCQRIKKNEKIEYNSSDEFSDDSLIELLNETQTQVEPNTIEQDL-DKVEKMVS--DD 394

  Fly    68 MDVSKESSCTA----------RKGVITSLDGDRGVIDKDVLFETKVAEDIILDLHVG------CV 116
            :.::.:|:.:|          |.||:..:     ::....:...|:....||:...|      .|
Yeast   395 LRIATDSTLSAYALRAKSGAPRDGVVRLV-----IVSLRSVELPKIGTQKILECIDGKGEQSSVV 454

  Fly   117 VE----YLTFTTGEAMRVVKVKSI-LEHSWEDTSQKEIEKAVDNLKNEKPTFFNTET-------- 168
            |.    ||.|..|:.:.:::.|:| .:....|....:.:.|.|||....|....:.|
Yeast   455 VRHPWVYLEFEVGDVIHIIEGKNIENKRLLSDDKNPKTQLANDNLLVLNPDVLFSATSVGSSVGC 519

  Fly   169 --RSVL------------------GLISQRLASSIDVETEYGQLTVE-----LD----------- 197
              ||:|                  .::.:.|..||..:..:.::::|     ||
Yeast   520 LRRSILQMQFQDPRGEPSLVMTLGNIVHELLQDSIKYKLSHNKISMEIIIQKLDSLLETYSFSII 584

  Fly   198 --NIEMNFIPTNGDRVRLECNIQLDDGFVDKQG-----EILEVTKLFPTRIQ---EGEKCIVERV 252
              |.|:.::.....:...|..:...:.||.|..     .|....:..|..|.   :.|:.|...:
Yeast   585 ICNEEIQYVKELVMKEHAENILYFVNKFVSKSNYGCYTSISGTRRTQPISISNVIDIEENIWSPI 649

  Fly   253 Y---------VHMVVLGPETYILKTDLPTG----TDLHLGDIVLADLIECQYSKFTRRAIKITPL 304
            |         |...|...:.:|:..::.||    ....:..::...|:..:|.         .|:
Yeast   650 YGLKGFLDATVEANVENNKKHIVPLEVKTGKSRSVSYEVQGLIYTLLLNDRYE---------IPI 705

  Fly   305 EKNFGATKLTQQSSMGSSGSGKAVTVTGVNRFITAELWQKESVSLKLTNNLNRT----------- 358
            |  |.....|:..:|....|        |...|...|..:..:|:...:.|...
Yeast   706 E--FFLLYFTRDKNMTKFPS--------VLHSIKHILMSRNRMSMNFKHQLQEVFGQAQSRFELP 760

  Fly   359 --LRLESITVCNDSESQLSVVSPLESKEISSGSEITVTFEIHTQFLGEAIEKYVLNF----DLLK 417
              ||..|...|...||.:.:...||.........:...|||.|..|.:.:..|...|    ||
Yeast   761 PLLRDSSCDSCFIKESCMVLNKLLEDGTPEESGLVEGEFEILTNHLSQNLANYKEFFTKYNDL-- 823

  Fly   418 VRRVFTVIVCKTKE-----------------------EVAEAEKRMIAAEALMAPGRNSQERSRF 459
            :.:..:.|.|..||                       ||.|.||...|.....:..||.......
Yeast   824 ITKEESSITCVNKELFLLDGSTRESRSGRCLSGLVVSEVVEHEKTEGAYIYCFSRRRNDNNSQSM 888

  Fly   460 YANQVWCNKVDVIPGQQIVTKRRFVALRLGCFEVPKELRQICLTSERRQEMIKAIEQHYSFLTEP 524
            .::|:..|...:|..::            |.|         ||...|.|           |:...
Yeast   889 LSSQIAANDFVIISDEE------------GHF---------CLCQGRVQ-----------FINPA 921

  Fly   525 ---LSIKTYMHRFRLLLHLEEIECFVNFRNYDRDRAHFLRDGEFLTLQIE-NLAERRPSLVIGDT 585
               :|:|..:...|||...:.:....:....:.:::..:.....:|.:|: |..::..||...:.
Yeast   922 KIGISVKRKLLNNRLLDKEKGVTTIQSVVESELEQSSLIATQNLVTYRIDKNDIQQSLSLARFNL 986

  Fly   586 LRVINPWSDP-----DSQT-----TKSYEG---IIHKVLFDRILLKFHSSFQEKYNGEDYRLEFY 637
            |.:..|...|     |.::     ||..:|   |:..:|.|....||..:
Yeast   987 LSLFLPAVSPGVDIVDERSKLCRKTKRSDGGNEILRSLLVDNRAPKFRDA--------------- 1036

  Fly   638 FSRYSFRKQHHAISKIVGVMGEDFLFPSKVTKRENPQLDVYMKDDDMYLYDSKLEWYNQSLNSIQ 702
                                .:|.:.|.|::|                         :.:||..|
Yeast  1037 --------------------NDDPVIPYKLSK-------------------------DTTLNLNQ 1056

  Fly   703 KRAVFNILRGEAENIPYVL-FGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRL 766
            |.|:..::|.|    .|.| .|.||:|||..:.|.:..||..  |.|:|:.:.::|:.|.:..:|
Yeast  1057 KEAIDKVMRAE----DYALILGMPGTGKTTVIAEIIKILVSE--GKRVLLTSYTHSAVDNILIKL 1115

  Fly   767 IDSKALLQGDFIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDKMMVTESGLKLRCQAKFIG 831
            .::..    ..:||...::|.     |:...|  ..:..:|.|..|.:             ..|.
Yeast  1116 RNTNI----SIMRLGMKHKVH-----PDTQKY--VPNYASVKSYNDYL-------------SKIN 1156

  Fly   832 THRITISTCTTLGNFLQLGFPAGH--FTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQ 894
            :..:..:||..:.:.|   |....  |.:|:.|||.|.:.|..:.|:    :..::.::.||..|
Yeast  1157 STSVVATTCLGINDIL---FTLNEKDFDYVILDEASQISMPVALGPL----RYGNRFIMVGDHYQ 1214

  Fly   895 LQSIVTSRIASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYS 959
            |..:|.:..|...|         ||.|.::...::.|||       :.:|...||....|:::.:
Yeast  1215 LPPLVKNDAARLGG---------LEESLFKTFCEKHPES-------VAELTLQYRMCGDIVTLSN 1263

  Fly   960 RLFYDDELIPVLSEKDSRESRLLSKLRC----VFESEKDIPQAHGTFFYGIIGENRQNNDSPSWF 1020
            .|.||                  :||:|    ||....::|.......|     ..::.:|..|.
Yeast  1264 FLIYD------------------NKLKCGNNEVFAQSLELPMPEALSRY-----RNESANSKQWL 1305

  Fly  1021 NPQEVRE-----VFL------------------------MTI----ALYRANVTADQIGIITPYQ 1052
              :::.|     |||                        :|:    .:..:.|..:.||::|.|:
Yeast  1306 --EDILEPTRKVVFLNYDNCPDIIEQSEKDNITNHGEAELTLQCVEGMLLSGVPCEDIGVMTLYR 1368

  Fly  1053 KQVKMLRSMF-----IGTDVVMPKIGSVEEFQGQERDIILISTVRSSEEI----LRMDARFSLGF 1108
            .|:::|:.:|     .|.:::     :.::|||:::..|:||.||.:.::    |..:.|
Yeast  1369 AQLRLLKKIFNKNVYDGLEIL-----TADQFQGRDKKCIIISMVRRNSQLNGGALLKELR----- 1423

  Fly  1109 VRCSKRLNVAVSRARAMMIIFGNPHLL-AVDECWRQLILFCVKNNAYFGC 1157
                 |:|||::||::.:||.|:...: :|.|....:.|...:|..|..|
Yeast  1424 -----RVNVAMTRAKSKLIIIGSKSTIGSVPEIKSFVNLLEERNWVYTMC 1468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	50/206 (24%)
		AAA_19	720..768	CDD:289986	16/48 (33%)
		DNA2	<840..1155	CDD:224037	77/363 (21%)
		UvrD_C_2	909..1132	CDD:304668	55/268 (21%)
DNA2	NP_012034.1	DNA2	551..1481	CDD:224037	212/1123 (19%)
		DEXXQc_DNA2	1052..1253	CDD:350799	59/253 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810