Protein Alignment armi and HELZ2

DIOPT Version :9

• Sequence 1: NP_001014556.1
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_024307774.1
• Gene: HELZ2 / 85441
• HGNCID: 30021
• Length: 2677
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 137/570 - (24%)
• Similarity: 220/570 - (38%)
• Gaps: 147/570 - (25%)

  Fly   694 YN-----QSLNSIQKRAVFNILRGEAENIPY-VLFGPPGSGKTMTLIETLLQL------------ 740
            ||     ..||..|     |:...||...|: |:.||||:|||:..:..:...
Human  2172 YNIPGGRHKLNPSQ-----NVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGG 2231

  Fly   741 ----VRNLPGARILVGTPSNSSAD----LVTKRL---------------------IDSKALLQ-- 774
                .:.|.|..||...|||.|.|    |:.:|:                     :.|:.||:
Human  2232 PPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 2296

  Fly   775 ------GDFIRLVSYNQVEKDLIPP---EIMSYCATSDVGAVGSCED----KMMVTESGLKLRCQ 826
                  ...:|.::.:...:....|   ||.::......|.:.|.||    |.::.|:
Human  2297 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEA------- 2354

  Fly   827 AKF-IGTHRITISTCTTLGN----FLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQV 886
            .|| :..|.:.:.||:...:    .|.:       ..:|.||||..|||||::|:|.. .:..:|
Human  2355 RKFELDRHEVILCTCSCAASASLKILDV-------RQILVDEAGMATEPETLIPLVQF-PQAEKV 2411

  Fly   887 VLSGDPRQLQSIVTSRIASKMGFSISFLERLLE-----RSPYR--KDLQRFPESSGYNPLVLTKL 944
            ||.||.:||:.:|.:.....:|...|..||..|     .:.||  :.:..||..:.|...:  |.
Human  2412 VLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKL--KT 2474

  Fly   945 LYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTFFYGIIGE 1009
            ....|..||::....:     |..||:........|.|                       ::..
Human  2475 WQGLRRPPSVLGHAGK-----ESCPVIFGHVQGHERSL-----------------------LVST 2511

  Fly  1010 NRQNNDSPSWFNPQEVREVFLMT--IALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKI 1072
            :..|.:|.:  |.:||.||..:|  :.|.| .|....|.::|||..|...:........:....:
Human  2512 DEGNENSKA--NLEEVAEVVRITKQLTLGR-TVEPQDIAVLTPYNAQASEISKALRREGIAGVAV 2573

  Fly  1073 GSVEEFQGQERDIILISTVRSSEEILRMDARFS-------LGFVRCSKRLNVAVSRARAMMIIFG 1130
            .|:.:.||.|...:|:||||:..: ..:|.|.:       ||||....::||||:||:..:.:.|
Human  2574 SSITKSQGSEWRYVLVSTVRTCAK-SDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIG 2637

  Fly  1131 NPHLLAVDECWRQLILFCVKNNAYFGCDLPQMVINQKDEVPVCLETFVPS 1180
            :..||.....||.|:.||.          .|..:....:|.||....:||
Human  2638 DHLLLRCCPLWRSLLDFCE----------AQQTLVPAGQVRVCRRPTMPS 2677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	65/265 (25%)
		AAA_19	720..768	CDD:289986	19/88 (22%)
		DNA2	<840..1155	CDD:224037	86/334 (26%)
		UvrD_C_2	909..1132	CDD:304668	56/238 (24%)
HELZ2	XP_024307774.1	ZnF_U1	39..69	CDD:197732
		AAA_11	541..705	CDD:331082
		UvrD_C_2	715..915	CDD:328976
		RNB	1334..1693	CDD:214935
		AAA_11	2180..2427	CDD:315699	65/266 (24%)
		AAA_12	2434..2639	CDD:315700	56/238 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810