Protein Alignment armi and SEN1

DIOPT Version :9

• Sequence 1: NP_001014556.1
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_013534.3
• Gene: SEN1 / 851150
• SGDID: S000004422
• Length: 2231
• Species: Saccharomyces cerevisiae
• Alignment Length: 1425
• Identity: 292/1425 - (20%)
• Similarity: 502/1425 - (35%)
• Gaps: 460/1425 - (32%)

  Fly    18 DILESLDRE---NSFLDQKLMEEKMDQQLKANPNEINGVL---SN-------------------- 56
            ::||::..:   .||.|..|:.:::...||    .|||:|   ||
Yeast   583 NVLENVTNKIDLRSFHDGPLLAKQLLVSLK----NINGLLIVPSNTAVAEAHNALNQKFLLLSTR 643

  Fly    57 ---KIAELTHG-----LSEMDVSKES-SC---------TARKGVITS-------LDGDRGVIDKD 96
               |.|::..|     |::.|.|:.. ||         .|...::.:       |:|...:::.:
Yeast   644 LMEKFADILPGQLSKILADEDASQGFWSCIFSSDKHLYQAATNILYNTFDVEGRLEGILAILNSN 708

  Fly    97 VLFETK-------------------VAEDIILDLHVGCVVEYLT--FTTGEAMRVVKVKSILEHS 140
            :....|                   .|..:::|: |...|:.::  |...:.::....:......
Yeast   709 LTVNLKNINVMLQRLINCEFYEPCPRAVRVLMDV-VSAFVDPISGVFANFQTLKSQNTEKEFLKF 772

  Fly   141 WE------DTSQKEIEKAVDNLKNEKPTFFNTETRSVLGLISQRLASSIDVETEYGQ-LTVELDN 198
            ||      ||..|...|........:...|..:|..    :|:.|   :|...|:.. |..:..|
Yeast   773 WESCWLFLDTIYKFTLKWASKYDYSELENFTKDTLD----LSRSL---VDSFREFSDILHDQTKN 830

  Fly   199 IEMNFIPT---------NGDRVRLE-C--------------NIQLDDGFVDKQGEILEVTKLFPT 239
            :.:|.:.|         ..|.|.|| |              ::::||..|:...:.....|.|..
Yeast   831 LLLNVLETFKNMLYWLRLSDEVLLESCVRLIISTSDLAHEKHVKVDDSLVEMMAKYASKAKRFSN 895

  Fly   240 RIQEGEKC-------IVERVYVHMVVLGPETYILKTDLPTGTDLHLGDIV-LADLIECQYSKFTR 296
            ::.|.:..       |..:.....|....|.|..:.:|.     .||.:: |.|.:....|....
Yeast   896 KLTEQQASEILQKAKIFNKALTEEVATEAENYRKEKELS-----RLGKVIDLTDSVPASPSLSPS 955

  Fly   297 RAIKITPLEKNFGATKLTQQSSMGSSGSGKAVTVTGVNRFITAELWQKESVSLKLTNNLNRTLRL 361
            .:..|........|..| |:.::.||       :||..|....::....:........|:||..:
Yeast   956 LSSTIASSSAESRADYL-QRKALSSS-------ITGRPRVAQPKITSFGTFQSSANAKLHRTKPV 1012

  Fly   362 ESITVCNDSESQL---SVVSP------------LESKEISSGSEITVTFEIHTQFLGEAIEKYVL 411
            :.::....:..||   .||.|            |.:|...|.||.:
Yeast  1013 KPLSKMELARMQLLNNRVVHPPSAPAFHTKSRGLSNKNDDSSSEES------------------- 1058

  Fly   412 NFDLLKVRRVFTVIVCK-----TKEEVAEAEKRMIAAEALMAPGRNSQERSRFYANQVWCNKVDV 471
            :.|:...|.:|.:...|     |.:...:..||..|||  :|.......|.|.        .||:
Yeast  1059 DNDIESARELFAIAKAKGKGIQTVDINGKVVKRQTAAE--LAKQELEHMRKRL--------NVDM 1113

  Fly   472 IPGQQIVTKRRFVALRLGCFEVPKELRQICLTSERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRL 536
            .|..:|:.:..:....    |.|.:            |.|........|...|..   |....:.
Yeast  1114 NPLYEIILQWDYTRNS----EYPDD------------EPIGNYSDVKDFFNSPAD---YQKVMKP 1159

  Fly   537 LLHLEEIECFVNFRNYDRDRAHFLRDGEFLTLQIENLAERRP-SLVIGDTLRVINPWSDPDSQTT 600
            ||.||..:...:    .|||..:                 :| |:::|:...|        |...
Yeast  1160 LLLLESWQGLCS----SRDREDY-----------------KPFSIIVGNRTAV--------SDFY 1195

  Fly   601 KSYEGIIHKVL-------FDRILLKFHSSFQ--EKYNGEDYRLEFYFSRYSFRKQH--------- 647
            ..|..:..:|:       .|.|::.:...|:  ::.:.:|::          :.||
Yeast  1196 DVYASVAKQVIQDCGISESDLIVMAYLPDFRPDKRLSSDDFK----------KAQHTCLAKVRTL 1250

  Fly   648 -----------------HAISKIVGVMGEDFLFPSKVTKRENPQLDVYMKDDDMYLYD------- 688
                             |:.||.:.:..|  ::..||.:....:.: |...:.:..||
Yeast  1251 KNTKGGNVDVTLRIHRNHSFSKFLTLRSE--IYCVKVMQMTTIERE-YSTLEGLEYYDLVGQILQ 1312

  Fly   689 -----------SKLEWYNQS--LNSIQKRAVFNILRGEAENIPYVLFGPPGSGKTMTLIETL--- 737
                       :::|...:|  ||:.|..|:.|.:..|..::   :.||||:|||.|::..:
Yeast  1313 AKPSPPVNVDAAEIETVKKSYKLNTSQAEAIVNSVSKEGFSL---IQGPPGTGKTKTILGIIGYF 1374

  Fly   738 -------------LQLVRN-------LPGARILVGTPSNSSADLVTKRLIDSKALLQG-----DF 777
                         :.|.:|       |...:||:..|||::.|.:..||.......||     ..
Yeast  1375 LSTKNASSSNVIKVPLEKNSSNTEQLLKKQKILICAPSNAAVDEICLRLKSGVYDKQGHQFKPQL 1439

  Fly   778 IRLVSYNQVE---KDLIPPEIM-------SYCATSDV-------GAV--------------GSCE 811
            :|:...:.|.   |||...|::       :|...:|.       .||              |:.|
Yeast  1440 VRVGRSDVVNVAIKDLTLEELVDKRIGERNYEIRTDPELERKFNNAVTKRRELRGKLDSESGNPE 1504

  Fly   812 DKMM---VTESGLKLRCQAKFIG----------------------------THRITIS--TCTTL 843
            ..|.   :::..||:|..:|.|.                            .|.:.:|  .|:||
Yeast  1505 SPMSTEDISKLQLKIRELSKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHILAVSDIICSTL 1569

  Fly   844 GN-----FLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTSRI 903
            ..     ...:|.   .|..|:.|||.||||..:::|:....|:   .::.|||.||...|.|..
Yeast  1570 SGSAHDVLATMGI---KFDTVIIDEACQCTELSSIIPLRYGGKR---CIMVGDPNQLPPTVLSGA 1628

  Fly   904 ASKMGFSISFLERLLER-SPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDEL 967
            ||...::.|...|:.:. |||..|:|                   ||..|||....|..||...|
Yeast  1629 ASNFKYNQSLFVRMEKNSSPYLLDVQ-------------------YRMHPSISKFPSSEFYQGRL 1674

  Fly   968 IPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFLMT 1032
                  ||.....:|:| |...:.|   |.|...||..|.|...||..:.|:.|.:|:|....:.
Yeast  1675 ------KDGPGMDILNK-RPWHQLE---PLAPYKFFDIISGRQEQNAKTMSYTNMEEIRVAIELV 1729

  Fly  1033 IALYR-----ANVTADQIGIITPYQKQVKMLRSMF-------IGTDVVMPKIGSVEEFQGQERDI 1085
            ..|:|     .:.|. :||||:||::|::.:|..|       |...:   ...:::.|||||::|
Yeast  1730 DYLFRKFDNKIDFTG-KIGIISPYREQMQKMRKEFARYFGGMINKSI---DFNTIDGFQGQEKEI 1790

  Fly  1086 ILISTVRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLI 1145
            ||||.||:.      |.:.|:||::..:|:|||::||:..:.:.|:...||..:.||.||
Yeast  1791 ILISCVRAD------DTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDLI 1844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	68/300 (23%)
		AAA_19	720..768	CDD:289986	19/70 (27%)
		DNA2	<840..1155	CDD:224037	100/324 (31%)
		UvrD_C_2	909..1132	CDD:304668	70/235 (30%)
SEN1	NP_013534.3	SEN1_N	106..859	CDD:403815	52/287 (18%)
		DNA2	1006..1858	CDD:224037	215/977 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341570
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740