DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment armi and zgc:154086

DIOPT Version :9

Sequence 1:	NP_001014556.1	Gene:	armi / 38427	FlyBaseID:	FBgn0041164	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_001070795.1	Gene:	zgc:154086 / 768184	ZFINID:	ZDB-GENE-061013-333	Length:	1106	Species:	Danio rerio

Alignment Length:	1177	Identity:	353/1177 - (29%)
Similarity:	557/1177 - (47%)	Gaps:	204/1177 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 RKGVITSLDGDRGVIDKDVLFETKVAEDIILD---LHVGCVVEYLTFTTGE-----AMRVVKVKS 135
            |.||:|.|..|.|:||..|.|    :...:|.   |.||..|:.|....||     |:||.:.|.
Zfish    43 RTGVVTHLCVDYGLIDHSVFF----SPTAVLGGAALAVGDTVQALAVRDGEHGQWRAIRVERDKD 103

  Fly   136 ILEHSWEDTSQKEIEKAVDNLKNEKPTFFNTETRSVLGLISQRLASSIDVETEYGQLTVELDNIE 200
                ||| :||.|    .||         ..:.|:::|.:     :|.|.:..|...|.......
Zfish   104 ----SWE-SSQSE----SDN---------QDKLRTLIGTV-----TSCDQDGGYINQTTYFPRSA 145

  Fly   201 M--NFIPTNGDRVR---LECNIQLDDGFVDKQGEILEVTKLFPTRIQEGE----KCIVER--VYV 254
            :  .|.|..||.|.   :.|.::...          |...:.|.|.:..:    .|::.:  |..
Zfish   146 LCEGFEPMKGDWVTAHYVVCPVEWSS----------EAKAVSPLRYRRMDGVSVTCVLSKTGVVE 200

  Fly   255 HMVVLGPETYILKTDLPTGTDLHLGDIVLADLIECQYSKFTRRAIKITPLEKNFGATKLTQ---- 315
            ..|....::.|    :|.|.....||:|...::|...|.::.||:.:|||:::...::..:
Zfish   201 DSVFFNLDSLI----VPPGFRPTRGDLVNLVVLESSQSLYSWRALCMTPLQRSAQCSEQKEPDAD 261

  Fly   316 -QSSMGSSGSGKAVTVTGVNRFI------TAEL--WQKESVSLKLTNNLNRTL----------RL 361
             |:.:...|   .:.|:..|:.:      .:||  |.:...|.:  ..|.|.:          .:
Zfish   262 LQALLQEKG---GLQVSQQNQSVCLLMGDCSELLIWVQNCGSER--QQLQRCVCAGWDSAQQFSV 321

  Fly   362 ESITVCNDSESQLSVVSPLESK-EISSGSEITVTFEIHTQFLGEAIEKYVLNFDLLKVRRVFTVI 425
            .|::.|.|..::...|..||.. :|..|.::.|......:.||.:.|..:|:|....:.|...:.
Zfish   322 RSVSRCEDGGTEAPPVRMLEEPLDIHPGQKMCVCVCCTAKTLGRSSELLLLHFSSFTIGRRLELS 386

  Fly   426 VCKTKEEVAEAEKRMIAAEALMAPGRNSQERSRFYANQVWCNKVDVI----PGQQIVTKRRFVAL 486
            |...:|::........:..   ||.:..|             .:.|:    |...:...||.:..
Zfish   387 VSSVEEQLLNPSMPYCSPS---APAQLPQ-------------PLQVLTVSAPPTPLRLTRRHLPN 435

  Fly   487 RLGCFEVPKELRQICLTSERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNFRN 551
            .||.:.||:.||: |:.:::...:::..      |.|.||::|.:.||..||.|||::.....|.
Zfish   436 FLGNYGVPQALRE-CVEAQKDVLVVQPA------LAEALSLRTMLPRFSALLWLEELQAEREIRE 493

  Fly   552 YDRDRAHFLRDGEFLTLQIENLAERRPSLVIGDTLRVINPWSDPDSQTTKSYEGIIHKVLFDRIL 616
            :....|...|...:|.|::..|||.||||.|||.:.:..|.|   ......|...:.::..:.:.
Zfish   494 FSLTGAILRRGAVYLHLEVPGLAEGRPSLFIGDKVVLKKPCS---GGVVIEYIAYVTEISDEDVS 555

  Fly   617 LKFHSSFQEKYNGEDYRLEFYFSRYSFRKQHHAISKIVGVMGEDFLFPSKVTKRENPQ------- 674
            |:.::.||..|.||...:||.|:|.:.|:.|.|:.:... .||:.|||| :.:.:.||
Zfish   556 LRVNAEFQSSYLGEPLDVEFSFNRLTMRRCHCALEQSKH-FGENILFPS-MLQLQAPQWSGEWGP 618

  Fly   675 ---LDVYMKD------------------------DDMYLYDSKL----EWYNQSLNSIQKRAVFN 708
               .|..:||                        .|:.:.:.::    :::|..||:.||:||..
Zfish   619 QEEQDEELKDGEQTQTVTGSALTAEMVSVATQTKTDLSVTEKRIPNPGQFFNPDLNAAQKQAVRR 683

  Fly   709 ILRGEAENIPYVLFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALL 773
            ||.||:...|||||||||:|||:||||.:||:...:..:|:||.|||||:|||:..||..|
Zfish   684 ILSGESRPTPYVLFGPPGTGKTITLIEAILQVHHRISCSRVLVCTPSNSAADLICMRLHHS---- 744

  Fly   774 QGDFIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDKMMVTESGLKLRCQAKFIGTHRITIS 838
              .|:...|..:|.....|.|.||             |:......:|..:| .|.|   |||.:|
Zfish   745 --GFLHSASLARVNATCRPEESMS-------------EELRQYARAGEDIR-HASF---HRIVVS 790

  Fly   839 TCTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTSRI 903
            ||::.|.|.|:|...||||||..|||||.|||||::|:.:|::...|:||:|||:||..:|.||:
Zfish   791 TCSSAGMFYQIGLRVGHFTHVFVDEAGQATEPETLIPLSLLSETSGQIVLAGDPKQLGPVVKSRL 855

  Fly   904 ASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDELI 968
            ||..|..:|.||||:..|.|...      ..|:|||::||||||||:..:::.:.|||||..||.
Zfish   856 ASVFGLGVSLLERLMGNSLYACG------ERGFNPLLVTKLLYNYRSHEALLDLPSRLFYAGELC 914

  Fly   969 PVLSEKDSRESRLLSKLRCVFESEKDIP-QAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFL-- 1030
                   .|..|......|.:..   :| :.....|:|:.|...:...:||||||.|..:|.:
Zfish   915 -------VRAQRAAVDSLCHWNK---LPTRGFPLIFHGVRGSEMREGCNPSWFNPAEAVQVMMYC 969

  Fly  1031 --MTIALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQGQERDIILISTVRS 1093
              :...||.. ::|..||:|.||:|||:.:|.:.....:...|:||||||||||..|:::|||||
Zfish   970 CQLAKRLYNP-ISAADIGVIAPYRKQVEKIRVLLQRVGLGEVKVGSVEEFQGQEFLIMILSTVRS 1033

  Fly  1094 SEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLILFCVKNNAYFGCD 1158
            :|.:|..:.:..|||:...||.|||::||:|::|:.||||:|..:.|:..|:.:...|.|:.|||
Zfish  1034 NESLLNEELQCMLGFLSNPKRFNVAITRAKALLIVIGNPHVLIKEPCFSALLQYSYDNRAFIGCD 1098

  Fly  1159 LPQMVIN 1165
            .|..:.|
Zfish  1099 PPVALQN 1105

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	91/203 (45%)
		AAA_19	720..768	CDD:289986	29/47 (62%)
		DNA2	<840..1155	CDD:224037	130/319 (41%)
		UvrD_C_2	909..1132	CDD:304668	85/227 (37%)
zgc:154086	NP_001070795.1	S1-like	45..97	CDD:291136	19/55 (35%)
		AAA_11	672..854	CDD:289831	91/204 (45%)
		P-loop_NTPase	673..>850	CDD:304359	90/199 (45%)
		AAA_12	861..1072	CDD:289832	85/227 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010