Protein Alignment armi and helz2a

DIOPT Version :10

• Sequence 1: NP_647816.2
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_003198895.2
• Gene: helz2a / 562461
• ZFINID: ZDB-GENE-120920-1
• Length: 2656
• Species: Danio rerio
• Alignment Length: 1183
• Identity: 252/1183 - (21%)
• Similarity: 420/1183 - (35%)
• Gaps: 357/1183 - (30%)

  Fly    92 VIDK-DVLFETKVAEDIILDLHVGCVVEYLTFTTGEAMRVVKVKSILEHSWEDTSQKEIEKAVDN 155
            |||| ||.:.|       ||:::.|                     ||.|.::..|...|:..:.
Zfish  1695 VIDKTDVKYTT-------LDINLSC---------------------LEFSRKNDQQSAYERKANA 1731

  Fly   156 LKNEKPTFFNTETRSVLGLISQRLASSIDVETEYGQLTVELDNIEMNF---IPTNGDRVRLECNI 217
            |.                 .:.:|:|..:.:..|   .|||:.:..||   .|.|...:....:|
Zfish  1732 LH-----------------FALKLSSQSERKVAY---IVELNPLGTNFKVSFPLNRSSISENLDI 1776

  Fly   218 QLDDGFVDKQGEILEVTKLFPTRIQEGEKCIVERVY------VHMVVLGPETYILKTDLPTGTDL 276
            ...|..:..|.| .:||.  .:.|.:.|:    |:|      :|..|.......:...:|..|..
Zfish  1777 MSRDLLLAVQPE-FDVTN--NSMILKWER----RIYSFSNSHIHAEVKQQNPNSVMAYVPAKTWK 1834

  Fly   277 HLGDIV-------LADLIECQYSKFTRRAIKITPLEKNFGATKLTQQSSMGSSGSGKAVTVTGVN 334
            .:.|.:       :..|||              .|::|.|........::.:|...|........
Zfish  1835 CIADAIREQNWNAIFPLIE--------------ELQRNSGINARQFHETLSASKCTKNYDPLHAE 1885

  Fly   335 RFITAELW----QKESVSLKLTNNLNRTLRLESITVCNDSESQLSVVSPLESKEISSGSEITVTF 395
            .:  |||:    |.|:|.::|..:..|.|...||        ||.||.|              .|
Zfish  1886 HY--AELYLRIKQGEAVEVQLGASTARGLMTPSI--------QLFVVHP--------------KF 1926

  Fly   396 EIHTQFLGEAIE---KYVL-----NFDLLKVRRVFTVIVCK---TKEEVAEAEKRMIAAEALMAP 449
            ||..:.:.:.::   :|.|     :::|.|..:.....:|:   ....|||.|..:|....|...
Zfish  1927 EICVEHVRDPVKCFSEYALSSSRSSYNLYKDYQAIWRPMCEMESASSAVAENESILIVDVPLKWE 1991

  Fly   450 GRNSQERSRFYANQVWCNKVDVIPGQQIVTKRRFVALRLGCFEVPKELRQ--ICLTSERRQEMIK 512
            ..|.:....|:          ::|    :.|:       ..:.:..:||.  :|:.:..:::...
Zfish  1992 NSNPKRLQGFF----------LLP----LDKK-------SQWSIDCDLRNSFLCIRTRIQKQSSP 2035

  Fly   513 AIE--QHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNFRNYDRDRAHFLRDGEFLTLQIENLAE 575
            .:|  |:.:.:..| |....:|  .::...||.|            :....:.|..:|:|:.|..
Zfish  2036 FLESAQNTALMDIP-SFTWVVH--GVITEAEETE------------SKESTNQEPKSLRIDFLIN 2085

  Fly   576 RRPSLVIGDTLRVINPWSDPDSQTTKSYEGIIHKVLFDRILLKFHSSFQEKYNGEDYRLEFYFSR 640
            ..|...|.:.:         ..:.|:....:|.|:|.|          ..|.|..|
Zfish  2086 HMPMTNIPEQI---------FHERTRFTLELIPKLLPD----------VRKENAID--------- 2122

  Fly   641 YSFRKQHHAISKIVGVMGEDFL------FPSKVTKRENPQLDVYMKDDDMYLYDSKLEWYNQS-- 697
             |..|.:..:..|  .||....      .|::.|.|                  .::..|:.|
Zfish  2123 -SLTKANQLVKNI--AMGRRITSDRGCKIPNQNTGR------------------FEINSYHPSGL 2166

  Fly   698 --LNSIQKRAVFNILRGEAENIPYVLF-GPPGSGKTMTLIETLLQLVRNL-----PGAR---ILV 751
              ||:.|.:|:     .||...|:.|. ||||:|||:..:..|..|.:|:     .|::   ||.
Zfish  2167 SHLNNSQSKAI-----REALTNPFTLIQGPPGTGKTVVGVHILYWLHKNIQQLQASGSKKRAILY 2226

  Fly   752 GTPSNSSADLVTKRLI-------------DSKALLQ---------------------GDFIRLVS 782
            ..|||.|.|:|...|:             |...:|:                     .:...:..
Zfish  2227 CGPSNKSVDVVAGHLLHLRDHLKPLRVYSDQMEMLEFPYPGCNLKLSRNSKRGEKPNTELSSIAL 2291

  Fly   783 YNQVEKDLIP--PEIMSYCATSDVGAVGSCEDKMMVTESGLKLRCQAKFIGTHRITISTCTTLGN 845
            ::.:.|:..|  .:|.::......|...:.|::.:..|...|.|...  :..|.:.:.|||.
Zfish  2292 HHLIRKEGNPFSTQIRAFDMKVQRGDQLTDEERKLFREILKKARKHE--LLHHDVILCTCTA--- 2351

  Fly   846 FLQLGFPAGH--------FTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTSR 902
                   |.|        |..::.||....||||..:|:|  ..|..|:||.||.:|||.:|...
Zfish  2352 -------ASHPALAETLDFKQIIIDECAMATEPEAFIPLV--AHKPEQIVLLGDHKQLQPVVHCE 2407

  Fly   903 IASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDEL 967
            :|.::|.|.|..||.:|                 |.|:|..   .||....|.:..|..||...|
Zfish  2408 VAERLGMSRSLFERYME-----------------NALMLDT---QYRMQEDICAFPSNEFYGGRL 2452

  Fly   968 ---IPVLSEKDSRESRLL---SKLRCVF-----ESEKDIPQAHGTFFYGIIGENRQNNDSPSWFN 1021
               ||.       :|:|.   :|..|:.     ..||           .::....|.|:: |..|
Zfish  2453 QTGIPA-------KSKLFLTQTKQTCIVFGHVEGKEK-----------SLVVRTEQGNEN-SKAN 2498

  Fly  1022 PQEVREVFLMTIALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQGQERDII 1086
            .:|..||..:.|.|..|.:....|.|:|||..||..:........:....:.::...||.|...:
Zfish  2499 MEEAEEVVRVAILLTEAGIKTKDIAILTPYNAQVAKISESLHNNHIRDITVNTIMRSQGSEWRYV 2563

  Fly  1087 LISTVRS--SEEILRMDARF----SLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLI 1145
            ::|||||  ..||.....:.    .|||:....::||.::||:..:.|.||.:||.....||:|:
Zfish  2564 IMSTVRSCPKSEIETQPPKSWIMKRLGFITDPHQVNVGITRAQEGLCIIGNENLLRCSSLWRKLL 2628

  Fly  1146 LF-----CVKNNA 1153
            ..     ||.|.|
Zfish  2629 NHYQEKGCVVNPA 2641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_647816.2	DEXXQc_Mov10L1	697..949	CDD:350836	74/308 (24%)
		DNA2	<829..1148	CDD:440729	92/348 (26%)
helz2a	XP_003198895.2	DNA2	296..1038	CDD:440729
		DEAD-like_helicase_N	616..846	CDD:475120
		RNB	1338..1698	CDD:214935	2/2 (100%)
		DEAD-like_helicase_N	2169..2434	CDD:475120	73/303 (24%)
		AAA_12	2414..2614	CDD:463780	58/238 (24%)