Protein Alignment armi and helz2c

DIOPT Version :10

• Sequence 1: NP_647816.2
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001428512.1
• Gene: helz2c / 552926
• ZFINID: ZDB-GENE-050508-3
• Length: 1546
• Species: Danio rerio
• Alignment Length: 1364
• Identity: 274/1364 - (20%)
• Similarity: 467/1364 - (34%)
• Gaps: 409/1364 - (29%)

  Fly    72 KESSCTARKGVITSLDGDRGVIDKDV-------LFETKVAEDIILDLHVGCVVEYLTFTTGEAMR 129
            |.|...:.:..:|.::.||.:..|:.       ..||   |.:.......||.  :.:...||.|
Zfish   323 KTSQIRSTQFALTLINSDRRMSYKEADQIIQKYFSET---EPLRFSRLEDCVA--VAYRFSEAHR 382

  Fly   130 VVKVKSILEHSWEDTSQKEIEKAVDNLKNEKPTFFNTETRSVLGLISQRLASSIDVETEYGQLTV 194
                ||.||..|:...|.|                  :||      ||.:..  ::.|.|.....
Zfish   383 ----KSRLEGGWQCGRQVE------------------QTR------SQAMVE--ELMTLYNSAAA 417

  Fly   195 ELDNIEMNFIPTNGDRVRLECNIQLDDG----FVDKQGEILEVTKLFPTRIQE------------ 243
            |    |:.......|...|.|:...|..    |.:|..:::.::..|.....|
Zfish   418 E----ELISADVTKDLTPLRCHQGPDPNLLIQFKEKYTDLIPMSAYFSNMFDENMEYNPEHDGFE 478

  Fly   244 --GEKCIVERVYVHMVVLGPETYILKTDLPTGTDLHLGDIVLADLIEC--QYSKFTRRAI---KI 301
              |....:....:|.:    |.:....|..:.|.|...|.:...|:..  .:.:..|:|:   ..
Zfish   479 HSGMPFTIFTSILHKM----EEFAQSRDYYSLTQLIFSDEIHPTLVPMVRDFREIKRKAVILRSC 539

  Fly   302 TPLEKNFGATKLTQQSSMGSSGSGKAVTVTGVNRFITAELWQKESVSLKLTNN-LNR-------- 357
            |..|...|...|...:...:|...:......|.|.:...|.::.......||: :||
Zfish   540 TSKESRLGHYDLQMNAYTWASSPMRRYLDLIVQRLLHTMLSKQYLKQADYTNDEINRYCLSGMEA 604

  Fly   358 -------TLRLESITVCNDSESQLSVVSPLESKEISSGSEITVTFEIHTQFLGEAIEKYVLNFDL 415
                   ..||..|.........|:.|..:..|    |.|..::|.     |..:::...:.:..
Zfish   605 EEEQDALVFRLRKIQFEPRDVVNLATVDQITPK----GHEFIISFP-----LQPSLDLITIMYKH 660

  Fly   416 LKV------------------RRVFTV-IVCKTK------EEVAEAE----KRMIAA-------- 443
            |||                  |||:|. .|.|.:      :.|....    ||:|:|
Zfish   661 LKVVDQPKYNEDKNSMTLHWKRRVYTFGEVFKNRFPSNPMKNVTPVSSILWKRLISAVKHQDWAK 725

  Fly   444 ----------------EALMAPGRNSQERSRFYANQVWCNKVDVIPGQQIVTKRRFVALRLG--- 489
                            |.|::...::||.|:.:..::   .:::..|.       .|.::||
Zfish   726 IEQCFQNIKREEKPEMEKLISEASSTQENSKMHYKEL---NLELKLGD-------VVQVQLGSEF 780

  Fly   490 ----------------CFEVPKELRQ---------ICLTS----ERRQEMIK------------- 512
                            |||:..|..:         :|:.|    |..:|..|
Zfish   781 KDGLPVPVVQLLSVNECFEICLEHSRNPTLCFSDSVCIASKISYESYEEYQKIWTQLCQIDTAYN 845

  Fly   513 AIEQHYSFLTE--------PLSIKTYMH-----RFRLLLHLEEIECF--VNFRNYDRDRAHFLRD 562
            |:|::.|.:.|        .::::.:.|     :.:..|..:...||  :..|....|
Zfish   846 ALEENNSVILEEVFINWSDEINLQGFFHLTKTQKTQWSLEFDLTNCFLCIRLRRQKLD------- 903

  Fly   563 GEFLTLQIENLAERRPSLVIGDTLRVINPWS-DPDSQTTKS------YEGIIHKVLFDRILLKFH 620
                    |||.:......:.| |:...|:: ...:.||||      .:|.|:..:..|.:....
Zfish   904 --------ENLGKHIDRSAVSD-LQGCLPFTWVAHAVTTKSKKKDANTKGRINFKITHRSMTYIP 959

  Fly   621 SSFQEKYNGEDYRLEFYFSRYSFRKQHHAISKIVGVMGEDFLFPSKVTKRENPQLDVYMKDDDMY 685
            :....|  |..:.:|....:..:..:..|::.:   ...:.|..|..|.:.....|..:::..:|
Zfish   960 ARIFNK--GTKFTIEVIPKKIPYLLREQAVANL---KRANNLVKSVATGKLELNDDADLRNISLY 1019

  Fly   686 LYDSKLEWYNQSLNSIQKRAVFNILRGEAENIPY-VLFGPPGSGKTMTLIETLLQLVR------- 742
            ..|..|..  .:||..||:||     .||...|: |:.||||:|||:..|..:.|..:
Zfish  1020 DVDKSLNL--PTLNMSQKKAV-----KEAMKKPFTVIQGPPGTGKTVVGIHIVFQFFKKNKDFMT 1077

  Fly   743 -----------NLP-GARILVGTPSNSSADLVTKRLIDSKALLQGDFIRLVSYNQVEKDLIP--P 793
                       |.| ...||...|||.|.|:|.::|:....:|:.  :|:.. :|:|....|  .
Zfish  1078 SFKPNHTNPDGNPPKKPAILYCGPSNKSVDIVAEQLLKLSGVLKP--LRIYC-DQMEMREFPYTG 1139

  Fly   794 EIMSYCATS-----------DVGAV-------GSCEDKMMVTESGLKL------RCQAKFIGTHR 834
            ..:..|..|           |:..:       ....:::...|..|.:      |...|....|.
Zfish  1140 SELKLCRRSLRDEKPKEELRDITLMYLVRKPENPFSEEIKALEKNLSVDQIDNYRKLLKKANQHE 1204

  Fly   835 I-----TISTCTT-----LGNFLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLS 889
            |     .:.||::     |...:.       |..:|.||....||||..:|:|  :....|:||.
Zfish  1205 IEKYDVVLCTCSSALKPELREVMD-------FRQILIDECAMATEPEAFIPLV--SHNPQQIVLL 1260

  Fly   890 GDPRQLQSIVTSRIASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLL-YNYRALPS 953
            ||.:|::.||........|...|..||.::                     |..:| ..||....
Zfish  1261 GDHQQIRPIVQCGHVKNKGMEKSLFERYMD---------------------LANMLDTQYRMHAE 1304

  Fly   954 IMSIYSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTFFYG---------IIGE 1009
            |.|..|..|||.:|      |...|....    |:....|: |.|   ..:|         ::..
Zfish  1305 ICSFPSDEFYDGKL------KTGAERGPC----CLLNKSKE-PTA---MLFGHIEGKEVSLVVST 1355

  Fly  1010 NRQNNDSPSWFNPQEVRE-VFLMTIALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIG 1073
            .:.|.:|.:  |.:|..: |.:..:.:.::.|:.:.|.|:|||..||..::......:|....:.
Zfish  1356 EKGNENSMA--NTEEAEQAVCVADLLIKQSGVSPEHIAILTPYNAQVSEIKMTLEKKNVRNVTVC 1418

  Fly  1074 SVEEFQGQERDIILISTVR--SSEEILRMDAR-------FSLGFVRCSKRLNVAVSRARAMMIIF 1129
            :|.:.||.|...:::||||  |:.:|.....|       ..||||..:.::|||::||:..:.|.
Zfish  1419 TVMKSQGSEWPYVIVSTVRSCSTSDIQAYRVRPHKAWLGKRLGFVTDANQVNVAITRAQDGLCIL 1483

  Fly  1130 GNPHLLAVDECWRQLI-----LFCVKNNA---------------YFGCDLPQMVINQKDEVPVC 1173
            ||..||...|.|.:|:     ..||.|.|               |.|        |||::...|
Zfish  1484 GNSDLLRCCELWDRLLDHYYRKSCVVNPASDIRVKAKASEGLAIYTG--------NQKEDTNFC 1539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_647816.2	DEXXQc_Mov10L1	697..949	CDD:350836	71/308 (23%)
		DNA2	<829..1148	CDD:440729	87/353 (25%)
helz2c	NP_001428512.1	None