DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment armi and CG6204

DIOPT Version :9

Sequence 1:	NP_001014556.1	Gene:	armi / 38427	FlyBaseID:	FBgn0041164	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_651229.2	Gene:	CG6204 / 42877	FlyBaseID:	FBgn0039165	Length:	903	Species:	Drosophila melanogaster

Alignment Length:	790	Identity:	182/790 - (23%)
Similarity:	305/790 - (38%)	Gaps:	195/790 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   440 MIAAEALMAPGRNSQERSRFYANQVWCNKVDVIPGQQIVTKRRFVALRLGCFEVPKELRQICLTS 504
            ::..:|..||  |.:|.....:::|    |..:...:.:.:..|:|   ...|..::||......
  Fly   222 LLGKDATKAP--NEEEDEGLVSDKV----VKYVNALRNLLREDFLA---PLVEFVQQLRSGTDVD 277

  Fly   505 ERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNFRNYDRDRAHFLRDGEFLTLQ 569
            |.:|:.:...:.|.:.  .|.......|....|    :::.....:|..:...:.::.|..|.|
  Fly   278 ELKQQGLLWSDVHLTL--NPQFANAQRHSLVFL----KVQFTKESKNAYKTWLNSIKSGTLLCL- 335

  Fly   570 IENLAERRPSLVIGDTLRVINPWSDPDS--------QTTKSYEGIIHKVLFDRILLKFHSS-FQE 625
                   ..||...|.:.....:::|:.        |..|.|.  |... ::|.|:.|.:. |.|
  Fly   336 -------TTSLAFDDLILASVGYTEPEKLKEDCLSVQIVKQYN--IGNA-YNRPLIMFQAPVFFE 390

  Fly   626 KYNGEDYRLEFYFSRYSFRKQHHAISKIVGVMGEDFLFPSKVTKRENPQLDVYMK-------DDD 683
            .|    .|:..|.|..|..|.......:.|.|.    .|.....:...:|...||       .:|
  Fly   391 PY----LRVHNYLSTCSTEKFPMGRYIVDGQME----IPPPAYMKPGVKLSFNMKPFTLDKLPED 447

  Fly   684 MYLYDSKLEWYNQSLNSIQKRAV---FNILRGEAENIPYVLFGPPGSGKT---MTLIETLLQLVR 742
            ::|        |:|..:..|.|:   |:|::           ||||:|||   :.|:.:|:|..:
  Fly   448 LHL--------NESQKTAFKEALCREFSIIQ-----------GPPGTGKTHLSVQLVNSLIQNAK 493

  Fly   743 NLPGARILVGTPSNSSAD--LVTKRLIDSKALLQGDFIR---LVSYN---QVEKDLIPPEI---- 795
            .|....|:|.|.:|:|.|  ||.......:.|..|:..|   :..:|   .::.:|:||.:
  Fly   494 ALGTGPIIVLTYTNNSLDKFLVKISRYTQEILRFGNQSRDPQISKFNLSTTIKPELVPPRLKRIW 558

  Fly   796 -MSYC-------------ATSDVGAVGSCEDKMMVTESGLKLRCQAKFIGTHRITI--------- 837
             :..|             |..| |:..|.:|.:...|   ||...|:.|.|.|:..
  Fly   559 WLVNCEYKEKFRNLQGLYANFD-GSEESYQDTLAAQE---KLNQVAERIETLRMVFQFFLAREKD 619

  Fly   838 -----STCTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQS 897
                 :||....|||   |.......|||:||.:..|...   :..||.....|:|.||.:|||.
  Fly   620 LLAMTTTCAARHNFL---FRLLQSKCVLFEEAAEIQEAHI---VACLTPHTEHVILVGDHKQLQP 678

  Fly   898 IVTSRIASKMGFSISFLERLLERS-PY-RKDLQRFPESSGYNPLVLTKLLYNYRALPS---IMSI 957
            ...||...:    ||..|||:... |: |.:||                 |..|:..|   :.||
  Fly   679 FSGSRKVPQ----ISLFERLIVAGLPFSRLNLQ-----------------YRMRSCISELLVPSI 722

  Fly   958 YSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTFFYGIIGENRQNNDSPSWFNP 1022
            |      |||:...|.|:..:.||:||               ..:|.       |:|......:.
  Fly   723 Y------DELLCSESVKEYEDIRLMSK---------------NLYFV-------QHNQPEHCMSD 759

  Fly  1023 QEVREVF-------LMTIALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQG 1080
            ..:..::       |....:.:|......|.|::||..|::.:::..........::.||:.|||
  Fly   760 MSIGNLYEAGVLAKLTEFLIQKAQYKHSDIVILSPYNGQIECIKNALPQNYRSTVQVASVDSFQG 824

  Fly  1081 QERDIILISTVRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLL--AVDECWRQ 1143
            .|.:|:|:|.|||:     :..|  :||:|.:.|:.||:||||..:.|.||..:|  ...:.|..
  Fly   825 LEANIVLLSLVRSN-----ISGR--IGFLRQANRVCVALSRARWALYIVGNVTILKDTFPKIWNP 882

  Fly  1144 LILFCVKNNA 1153
            ::....:|||
  Fly   883 IVKRLKENNA 892

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	64/249 (26%)
		AAA_19	720..768	CDD:289986	19/52 (37%)
		DNA2	<840..1155	CDD:224037	87/328 (27%)
		UvrD_C_2	909..1132	CDD:304668	59/234 (25%)
CG6204	NP_651229.2	AAA_11	449..679	CDD:289831	67/258 (26%)
		AAA_19	467..>513	CDD:289986	18/56 (32%)
		UvrD_C_2	688..869	CDD:304668	59/232 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438954
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10887
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840