DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment armi and CG6701

DIOPT Version :9

Sequence 1:	NP_001014556.1	Gene:	armi / 38427	FlyBaseID:	FBgn0041164	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster

Alignment Length:	724	Identity:	185/724 - (25%)
Similarity:	303/724 - (41%)	Gaps:	137/724 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   499 QICLTSERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNFRNYDRDRAHFLRDG 563
            |:||.|...|      .|:|......::.:......|.||.:|:||...::.:..:......:.|
  Fly   390 QMCLASFDNQ------YQNYCERGREITQENLTGTLRTLLQVEDIERLQHYLSLKQSEMELHQFG 448

  Fly   564 EFL---------TLQIENLAERRPSLVIGDTLRVINPWSDPDSQTTKSYE---GIIHKVL--FDR 614
            ..|         ::.:|::      |..||.:.:||...:|.|...|..|   .::...|  ||.
  Fly   449 RELSVKMQMGTTSMSVEDI------LSPGDDVLIINEKGNPKSAVRKMLENNNNVLELALKDFDS 507

  Fly   615 ILLKFHSSFQEKYNGEDYRLEFYFSR----------------------YS---------FRKQHH 648
            | |::..:........|.:...||:|                      |:         .|.|:.
  Fly   508 I-LRWARNVDGMVGSLDKQPRVYFARILGVSTQRVNITCERQLPDNTTYTLIFRPLRAVMRYQYR 571

  Fly   649 AISKIVGVMGED---FLFPSKVTKRENPQLDVYMKDDDMYLYDSKLEWYNQ--SLNSIQKRAVFN 708
            |:.::......|   .|||.::....              |....|:..|:  |.|..|.:||..
  Fly   572 ALQQLSFTRHSDVQRILFPGEIPNTP--------------LASGVLQLNNKLISTNPEQMQAVRQ 622

  Fly   709 ILRGEAENIPYVLFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALL 773
            |........||::|||||:|||.|::|.:.||..|.|...|||...||::.|.|..||:  :|:.
  Fly   623 IALSPRLKAPYIVFGPPGTGKTSTIVEAIYQLYINRPETHILVLAGSNTACDEVALRLL--RAIA 685

  Fly   774 QG------DFIRLVSYNQVEK-DLIPPEIMSYCATSDVGAVGSCEDKMMVTESGLKLRCQAKFIG 831
            :.      ...|:.|.|...: |.|...::.|              ..|.|   :......:.:.
  Fly   686 KAPQSQPRPLTRIFSANCDRRIDNIDDLLLEY--------------SNMYT---VHFYPAVQAVH 733

  Fly   832 THRITISTCTTLGNFLQLGFPAGH-FTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQL 895
            .:||.|.|.:..|.....||.|.: :|||..|||...||.|.::.|.........::||||.:||
  Fly   734 QYRIVICTLSLAGKLSTGGFAANNVYTHVFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQL 798

  Fly   896 QSIVTSRIASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSR 960
            ..::.|:.|::.|..::..||||:|..|:.:     |...||..|.|:|:.|:|:.|.|:|:|:.
  Fly   799 GPVLQSQRANEWGLGLTLFERLLQRKCYQVE-----EDGSYNASVQTRLIRNFRSHPEIVSLYNN 858

  Fly   961 LFYDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTF---FYGIIGENRQNNDSPSWFNP 1022
            ::|:..|          .:....::.|.|.:...:|.|  ||   |:.:.|.......|.|..|.
  Fly   859 MYYEGHL----------RTEAPMEIVCRFHNWFYLPNA--TFPIMFHSVFGTTMNTKSSVSLCNN 911

  Fly  1023 QEVREVF-----LMTIALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQGQE 1082
            :|:..|.     ||...|....:....||||:||:.|.:.::......:......||||.|||:|
  Fly   912 KEIDVVMDYVKDLMYFGLNGEKLLQTDIGIISPYKNQYQRIQEQLNMRNWSQIDCGSVELFQGKE 976

  Fly  1083 RDIILISTVRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLILF 1147
            :.:|::|.|||...        .|||:...:||||.:||..:::|:.|||..|:.:..::.:|..
  Fly   977 KHVIIVSFVRSFTP--------KLGFLNNERRLNVLLSRPISLLILIGNPRTLSQNSDFQHIIEM 1033

  Fly  1148 CVKNNAYFG 1156
            |.......|
  Fly  1034 CRNRKTLVG 1042

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	63/211 (30%)
		AAA_19	720..768	CDD:289986	23/47 (49%)
		DNA2	<840..1155	CDD:224037	95/323 (29%)
		UvrD_C_2	909..1132	CDD:304668	67/230 (29%)
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	174/677 (26%)
		AAA_19	618..687	CDD:289986	29/70 (41%)
		AAA_12	812..1019	CDD:289832	68/231 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438956
Domainoid	1	1.000	151	1.000	Domainoid score	I4307
eggNOG	1	0.900	-	-		E1_COG1112
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4684
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101029
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.600