Protein Alignment armi and Helz2

DIOPT Version :10

• Sequence 1: NP_647816.2
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001292205.1
• Gene: Helz2 / 296474
• RGDID: 1306056
• Length: 2944
• Species: Rattus norvegicus
• Alignment Length: 1314
• Identity: 253/1314 - (19%)
• Similarity: 460/1314 - (35%)
• Gaps: 399/1314 - (30%)

  Fly   109 LDLHVGC--VVEYLTFTTGEAMRVVK---VKSILEHSWEDTSQKEIEKAVDNLKNEKP------- 161
            :|||:||  ..|||..:| ..:|.|:   .:.||...::..::.::.:.| .|:...|
  Rat    28 VDLHLGCSRCTEYLNEST-YILREVEHTCSREILLARFKQAAKNKVWRKV-GLRPSFPIPVRYQV 90

  Fly   162 -----------------TFFNTETRSVL-------GLISQRLASSIDVETEYGQLTVELDNIEMN 202
                             ||.::...:::       .|...:|..::.......:|....|.|...
  Rat    91 CRYYSPGLGCKRHWNRCTFASSPEEALVWTFELKNNLTRLKLKEAVQGTRAPDRLQTPADTIRAE 155

  Fly   203 FIPTNGDRVRLECNIQLDDGF---------VDKQGEILEVTKLFPTRIQEGEKCIVERVYVHMVV 258
            |    |...:|.|.:    .|         ||.:|...: .::.||            :.:|::|
  Rat   156 F----GGHFQLLCAL----CFKCRPPCLCPVDSRGHCPK-HQICPT------------LLIHVIV 199

  Fly   259 LGPETYILKTDLPTGTDLHLGDIVLADLIECQYSKFTRRAIKITPLEKNFGATKLTQQSSMGSSG 323
            .|.:...::. .|.....|          ...|..|..|.:..     ..||::.....|.....
  Rat   200 EGQKRQFVEV-RPLPQKRH----------PLNYCMFVGRGVPC-----RHGASRCGYAHSAVEMA 248

  Fly   324 SGKAVTVTGVNR--FITAELWQKESVSLKLTNNLNRTLRL---ESITVCNDSESQLSVVSPLESK 383
            ..||..:.|:.|  .:|..|:.::  ..|.::.....::|   ..:..|:..|:..:..|.||..
  Rat   249 VWKAEQLDGLQRGDLLTYPLFGED--KQKASHGQPPAVKLYCHACLVTCSSQEAFENHCSSLEHA 311

  Fly   384 EISSGSEITVTFEIHTQFLGEAIEKYVL--NFDLLKVRRVFTVIVCKTKEEVAEAEKR------- 439
            ::.:..:: |..:.....:|  :.|:.|  ..||.:...|  .|...:|:|:.|..:|
  Rat   312 QMVAFDQV-VPRKHRAPPMG--LSKFELCPRPDLCEYGEV--CIKAHSKQELQEWVQRAQDMELR 371

  Fly   440 --------MIAAEA-LMAPGRNSQERSRFYAN-----QVWCNKVDVIPGQQIVTKR--------- 481
                    ::..:| |:|..|.|.:.....|.     .|.|.:..|...|:.:..:
  Rat   372 EQAAWQDGLVPYQARLLAEYRRSSKEVLVMAETVHGVSVTCQQPLVHQAQEKIQHKWVFTIHSED 436

  Fly   482 ----------------RFVALRLGCFEVPKELRQICLTSERRQEMIKAIEQHYSF---------- 520
                            ..||..|...::..:.:..|:.:...|..:..:.|..||
  Rat   437 PLLHVALLKQEPGAAFSLVAPHLPPHQLYAQGKHFCVPNSPAQFQVGVLVQAASFGSFEQWVVFD 501

  Fly   521 ------LTEPLSIKT-YMHRFRL-----LLHLEEIECFVNFRNYDRDRAHFLRDGEFLTLQIENL 573
                  |.:.|.::. ..|...|     ..|.:|.||      :.....|.:.:.::...|...:
  Rat   502 FGRRPVLLQKLKLQLGQTHSLGLNGKPAPSHPQEREC------WHTGNRHVVLEVDWTPEQEALM 560

  Fly   574 AE-RRPSLVIGDTLRVINPWSDPDSQTTKSYEGIIHKVLFD----------------RILLK--- 618
            |: :.|||.:..:..|: .|. |.|:|  :|...:||.|::                ::.||
  Rat   561 AKYKLPSLALEFSHNVV-VWG-PISRT--NYRQRMHKFLYEEEAAQQQLVAKLAMKGQVSLKTAL 621

  Fly   619 --------------------FHSSFQEKYNGEDYRLEFYFSR-----------------YSFRKQ 646
                                |.||..     .|....|..||                 |..|.:
  Rat   622 ETPALGMLFAPPGALYAEVPFPSSLL-----PDTDQGFLMSRAVSTALVAPAPAPDSKVYQVRLE 681

  Fly   647 HHAISKIVGVMGEDFLFPSK------VTKRENPQLDVYMKDDDMYLYDSKLEWYNQSLNSI---- 701
            ..|.|:....:    |.|::      :..:::|.|:|..:.|.:.     ..:::::::::
  Rat   682 ARASSEHALWL----LLPARCCMALGLQAQDSPVLEVQFQIDPLI-----FRFWHRAVDALPEVC 737

  Fly   702 --------------------------QKRAVFNIL----RGEAENIPYVLFGPPGSGKTMTLIET 736
                                      ||.||..|.    .|.....|.:::||.|:|||.||...
  Rat   738 LVVPDLPACTLPHPWPTPPSFRGNHKQKLAVGLIAGRRPEGSKHIPPLLIYGPFGTGKTYTLAMA 802

  Fly   737 LLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALLQGDFIRLVSYNQVEKDLIPPEIM----- 796
            .|::|:. |..::|:.|.:||:||:..:.......            |...::..|..:|
  Rat   803 ALEVVQQ-PHTKVLICTHTNSAADIYVREYFHGYV------------NSGHQEAAPLRVMYADRP 854

  Fly   797 ---------SYCATSDVGAVGSCEDKMMVTESGLK--LRCQAKFIGTHRITISTCTTLGNFLQLG 850
                     .||..:        ||:.........  ||        ||:.:   ||.....:|.
  Rat   855 PRQTDSTTLQYCCLT--------EDRQAFRPPTFPELLR--------HRLVV---TTTSQARELQ 900

  Fly   851 FPAGHFTHVLFDEAGQCTEPETMVPI-VMLTKKRSQVVLSGDPRQ----LQSIVTSRIASKMGFS 910
            .|||.|:|:..|||.|..|.|.::|: ..||..|  |||:||..|    |.|:...:.|..|
  Rat   901 VPAGFFSHIFIDEAAQMLECEALIPLSYALTLTR--VVLAGDHMQVTPRLFSVPRDKAAGHM--- 960

  Fly   911 ISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLY--NYRALPSIMSIYSRLFYDDELIPV-LS 972
              .|.||.  ..|::::.:..:.|        ::::  |||:..:|::..||.||..:..|: .|
  Rat   961 --LLHRLF--LYYQQEVHKIAQHS--------RIVFHENYRSTAAIINFVSRHFYVAKGNPIQAS 1013

  Fly   973 EKDSRESRLLSKLRCVFESEKDIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFLMTIALY- 1036
            .|..|.                 ||.:...|..:.|...|:....||.|..||.:|......:|
  Rat  1014 GKVPRH-----------------PQHYPLMFCHVAGSPEQDMSRTSWLNSAEVTQVVEKVQEIYN 1061

  Fly  1037 ----------RANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQGQERDIILISTV 1091
                      :.::.|...|      .||..||......::....:||.|...|:|..::::|:|
  Rat  1062 TWPHCWGPREQRHICAVSHG------AQVSALRQELRRRNLGEVSVGSFEILPGREFRVVVLSSV 1120

  Fly  1092 RSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLL----AVDECWRQLILFCVKNN 1152
            .:...:|...|..|..|.. .:.||..::||::.::..|:...|    |..:.|:..|..|::::
  Rat  1121 HNRNSLLSPGAPTSEFFTE-PRVLNTVMTRAQSQLVAVGDAVALCSSGACRKLWKNFIRECIEHH 1184

  Fly  1153 AYFGCDLPQMVINQ 1166
            :.|..||....|.|
  Rat  1185 SIFPEDLSLEQIEQ 1198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_647816.2	DEXXQc_Mov10L1	697..949	CDD:350836	69/308 (22%)
		DNA2	<829..1148	CDD:440729	85/341 (25%)
Helz2	NP_001292205.1	DEAD-like_helicase_N	759..989	CDD:475120	69/278 (25%)
		AAA_12	974..1160	CDD:463780	47/217 (22%)
		RNB	1565..1923	CDD:214935
		DEXXc_HELZ2-C	2446..2721	CDD:350798
		AAA_12	2701..2906	CDD:463780