Protein Alignment armi and Helz

DIOPT Version :9

• Sequence 1: NP_001014556.1
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_008766536.1
• Gene: Helz / 287773
• RGDID: 1307049
• Length: 1981
• Species: Rattus norvegicus
• Alignment Length: 1159
• Identity: 263/1159 - (22%)
• Similarity: 444/1159 - (38%)
• Gaps: 292/1159 - (25%)

  Fly   178 RLASSIDVETEYGQLTVELDNIEMNFIPTNGDRVR-LECNIQLDDGFVDKQGEILEVTKLFPTRI 241
            |:||.:.:: .|||...:..::....:.......| :.|.:||       :|::..|:.:....:
  Rat    63 RIASFLQLK-NYGQADEDCRHVLGEGLAKGESAFRAVLCCMQL-------KGKLQPVSSILAQSL 119

  Fly   242 QEGEKC--IVERVYVHMVVLGPETYILKTDLPTGTDLHLGDIVLADLIEC--------------- 289
             .||..  :|.:....:..|..||....::.|:|  .|:.|:   |...|
  Rat   120 -SGESLNGMVTKDLTRLKTLLAETETATSNAPSG--CHVEDL---DEGSCNGWHFRPPPRGITSS 178

  Fly   290 -QYS---KFTRRAI--------------KITPLEKNFGA--TKLTQQS-SMGSSGSGKAVTVTGV 333
             :|:   :|..:.|              ::...:|.:.:  .||.||| :...|||.....:
  Rat   179 EEYTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQSENKQLSGSYMETLI--- 240

  Fly   334 NRFITAELWQKESVSLKLTNNLNRTLRLE-----SITV--------------------------- 366
                  |.|.......|:.:.....:::|     |:||
  Rat   241 ------EKWMSSLSPEKVLSECLEGVQVEHSPDLSVTVNTKKSHQTWTFALTCKPARMLCRVALL 299

  Fly   367 --------------CNDSESQLSVVSPLESKEISSGS-----------EITVTFEIHTQFLGEAI 406
                          ..||.:|:|...|...:|...|.           ::.:.|  :|:..|...
  Rat   300 YDAHRPHFSIIAISAGDSTAQVSQEVPENCQEWIGGEMAQNGLDHYVYKVGIAF--NTEIFGTFR 362

  Fly   407 EKYVLNFDLLKVRRVFTVIVCKTKEEVAEAEKRMIAAEALMAPGRNSQERSRFYANQVWCNKVDV 471
            :..|.:|.|..|.....:|...:.|::   |..|.|.:.|:...|..:..|:        ..||.
  Rat   363 QTIVFDFGLEPVLMQRVMIDAASTEDL---EYLMHAKQQLVTTARRWEPSSK--------TIVDF 416

  Fly   472 IPGQQIVTKRRFVALRLGCFEVPKELRQICLTSERRQEMIKA-----------IEQ--HYSFLT- 522
            .|.:....::..: :|   :::|....|:...|...:.:.|.           ||:  .|..::
  Rat   417 EPNETTDWEKSLL-IR---YQIPLSADQLFTQSVLDKSLTKTNYQSRLHDLLYIEEIAQYKEVSR 477

  Fly   523 ----EPLSIKTYMH--RFRLLLHLEEIECFVNFRNYDRDRAHFLRDGEFL-------TLQIENLA 574
                ||:.:...:|  :|.|.:.|:.:..|:  .......|.:.::|:..       ||..:.||
  Rat   478 LNGIEPVKVPICVHCAKFNLKVQLQILASFM--LTGVSGGAKYAQNGQLFGRFKLTETLSEDTLA 540

  Fly   575 ERRPSLVIGDTLRVINPWSDP-------DSQTTKS--YEGIIHKVLFDRILLKFHSSFQEKYN-- 628
            .|   ||:   .||...:..|       .||.||.  ||..|.:...|.:.|:......|:.:
  Rat   541 GR---LVM---TRVNAVYLLPVPKEKLVQSQGTKEKVYEATIEEKTKDYVFLRISRECCEELSLR 599

  Fly   629 ---GEDYRLEFYFSRYSFRKQHHAISKIV--GVMGEDFLFPSKVTKRENPQLDVYMKDDDMYLYD 688
               .....|:|..:|....:.|:|:.:|.  ||:..|......:....|.|.|
  Rat   600 PDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWD------------ 652

  Fly   689 SKLEWYNQSLNSIQKRAVFNILRGEAENIPYVL-FGPPGSGKTMTLIETLLQLVRNLPGARILVG 752
               |..:..||:.||.||..|.......:|.|| .||.|:|||.||.:.:..:::....:|||:.
  Rat   653 ---EQLDPRLNAKQKEAVLAITTPLCIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETSRILIC 714

  Fly   753 TPSNSSADLVTKRLID---SKALLQGDFIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDKM 814
            |.|||:|||..|..:.   .....|...:|:...|:..| .:.|.:..||..|...:......|
  Rat   715 THSNSAADLYIKDYLHPYVEAGNAQARPLRVYFRNRWVK-TVHPVVHQYCLISSAHSTFQMPQK- 777

  Fly   815 MVTESGLKLRCQAKFIGTHRITISTCTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVML 879
               |..||          ||:.:.|..|.....||....|.|||:|.|||.|..|.||::|:.:.
  Rat   778 ---EDILK----------HRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALA 829

  Fly   880 TKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKL 944
            | |.:::||:||..||...|.|..|.:....:|.|:||.|..|     ..||        ....|
  Rat   830 T-KNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYP-----AEFP--------CRILL 880

  Fly   945 LYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTF----FYG 1005
            ..|||:..:|::..|.|||:.:|:                     .|.|.  .||..|    |:.
  Rat   881 CENYRSHEAIINYTSELFYEGKLM---------------------ASGKQ--PAHKDFYPLTFFT 922

  Fly  1006 IIGENRQNNDSPSWFNPQEVREVFLMTIALYR------ANVTADQIGIITPYQKQVKMLRSMFIG 1064
            ..||:.|..:|.:::|..||.||......|.|      ..:....||::|||..||..:|:....
  Rat   923 ARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRK 987

  Fly  1065 ---TDVVMPKIGSVEEFQGQERDIILISTVRS------------SEEILRMDARFSL--GFVRCS 1112
               :||.:.::.:|   ||::..::.:||||:            .:|.|..|:...|  ||:...
  Rat   988 KRLSDVNVERVLNV---QGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNY 1049

  Fly  1113 KRLNVAVSRARAMMIIFGNP-HLLAVDEC---WRQLILFCVKNNAYFGCDLPQM 1162
            |.||.|::||::::.:.|:| .|.::..|   |.:.|..|.:|::..|....|:
  Rat  1050 KLLNTAITRAQSLVAVVGDPVALCSIGRCRKFWERFIALCHENHSLHGITFEQI 1103

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	69/207 (33%)
		AAA_19	720..768	CDD:289986	21/48 (44%)
		DNA2	<840..1155	CDD:224037	99/345 (29%)
		UvrD_C_2	909..1132	CDD:304668	65/249 (26%)
Helz	XP_008766536.1	zf-CCCH	181..205	CDD:395517	3/23 (13%)
		DEXXQc_HELZ	658..885	CDD:350835	81/255 (32%)
		SF1_C_Upf1	886..1086	CDD:350195	57/225 (25%)
		Atrophin-1	<1195..>1536	CDD:397323

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D286011at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820