DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment armi and eri-7

DIOPT Version :9

Sequence 1:	NP_001014556.1	Gene:	armi / 38427	FlyBaseID:	FBgn0041164	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_491374.2	Gene:	eri-7 / 172047	WormBaseID:	WBGene00016566	Length:	625	Species:	Caenorhabditis elegans

Alignment Length:	571	Identity:	136/571 - (23%)
Similarity:	246/571 - (43%)	Gaps:	104/571 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   668 TKRENPQ-------LDVYMKDD-DMYLYDSKLEWYNQSLNSIQKRAVFNILRGEAENIPYVLFGP 724
            |..:||:       |:.:|.|. ::..:||..:......::.::|....:...|...: ..:.||
Worm    27 TLEDNPESLTLQDVLESHMTDPIELNSFDSMEKEAGIPFSNEKQRTAIKMALNENRKL-VCIQGP 90

  Fly   725 PGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALLQ-GDFIR---LVSYNQ 785
            ||:|||.||...|.:|::.  ..:::|..|:..:  |...|::..|.|.: |..:.   |:..|:
Worm    91 PGTGKTFTLTLLLCRLIQQ--KKQVVVLAPTREA--LANIRMMTKKTLKRMGIKVHEHALMDTNE 151

  Fly   786 VEKDLIPPEIMSYCATSDVGAVGSCEDKMMVTESGL---------KLRCQ--AKFIGTHRITIST 839
            . :|:|.....:..|..:|..:....|...:||:.|         ::|.:  |:.||..|:..:
Worm   152 Y-RDVINKSDRALMAAEEVRDLRKAFDNGEITENVLDEMRQSIINRVRNEVGAEVIGNVRVAFA- 214

  Fly   840 CTTLG-NFLQLGFPAGHFTHVL--FDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTS 901
              |:| :|:........|...|  .|||.|..|.:|. |.|.   |..::|::|||:||.::|.:
Worm   215 --TIGASFVDFVMKHKKFDPCLCIIDEAAQVMEAQTW-PAVY---KMKRIVMAGDPKQLPALVFT 273

  Fly   902 RIASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDE 966
            ..|...|...|.::|:||:            .:.::.::|..   .||:...|.:..:..||.::
Worm   274 DEAKAFGLQNSVMDRILEK------------KNNFSWIMLEN---QYRSNAKIATWSNTCFYHNQ 323

  Fly   967 -----------LIPVLSEKDSRESRLLSKLRCVFES-EKDIPQAHGTFFYGIIGENRQNNDSP-- 1017
                       |..:|:.:..:...|...|..:..| |:|:.:...|:.:.:...|..|....
Worm   324 LKTDVKCHEYSLHTILNPQPKKFRNLFDPLVLIDTSLERDVEKRLETYEHAVFDTNSINKTKQGF 388

  Fly  1018 SWFNPQEVREVFLMTIALYRANVTADQIGIITPYQKQVKMLRSMF--IG-----TDVVMPKIGSV 1075
            |:.|..|.:........|.:..|....|.|||||:.|..::..:.  .|     ||.|...||:|
Worm   389 SYANLAEAKIAIGHYQRLLKYGVQPSDIAIITPYKGQTSLVTKLMEEFGAETGYTDFVQTTIGTV 453

  Fly  1076 EEFQGQERDIILISTVRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLA---- 1136
            :..||:|.::::.:.|||       :.|.::|||...:||||.::||:...:..||.:|||
Worm   454 DSVQGKEYEVVIFTMVRS-------NPRKTMGFVSELRRLNVVITRAKRHFMFIGNGYLLAESKK 511

  Fly  1137 -----VDECWRQLILFCVKNNAY-------------FGCDLPQMVINQKDE 1169
                 :.:|::........|||:             ||.||...:....||
Worm   512 DEIRKLYDCFKNAKRRFHPNNAFGEDGNVTDYVSNNFGQDLESFMNYSNDE 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	56/221 (25%)
		AAA_19	720..768	CDD:289986	15/47 (32%)
		DNA2	<840..1155	CDD:224037	87/360 (24%)
		UvrD_C_2	909..1132	CDD:304668	56/243 (23%)
eri-7	NP_491374.2	AAA_11	67..273	CDD:289831	56/218 (26%)
		AAA_19	77..131	CDD:289986	16/58 (28%)
		AAA_12	284..502	CDD:289832	55/239 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156474
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750