Protein Alignment armi and smg-2

DIOPT Version :9

• Sequence 1: NP_001014556.1
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_490829.1
• Gene: smg-2 / 171696
• WormBaseID: WBGene00004880
• Length: 1069
• Species: Caenorhabditis elegans
• Alignment Length: 1082
• Identity: 232/1082 - (21%)
• Similarity: 387/1082 - (35%)
• Gaps: 319/1082 - (29%)

  Fly   220 DDGFVDKQGEILEVTKLFPTRIQEGEKCIVERVYVHMVVLGPETYILKTD-LPTGTDLHLGDIVL 283
            ||.:....||.|.........:..|.....:..|....|  |......|| ||.|||....|:..
 Worm     5 DDEYSRSHGETLTFVDPEDDGVSIGNTQDSQFAYEQFSV--PTQSSQATDLLPGGTDGTTNDLPF 67

  Fly   284 ADL------------IECQYSKFTRRAIKITPLEKNFGATKLTQ------QSSMGSSGSGKAVTV 330
            .|:            .|.|..|....|.:...:.......|.|.      .|:.|:||.
 Worm    68 HDVEDDESDSEKSLTEEQQQQKLPEHACRYCGISDPLCVAKCTVCRKWFCNSNDGTSGG------ 126

  Fly   331 TGVNRFITAELWQKESVSLKLTNNLNRTLRLESIT----VCNDSESQLSVVSPLESKEISSGSEI 391
                               .:.:::.|:...|:.|    .|.|::        ||.....|
 Worm   127 -------------------HIVHHMVRSQHKEAYTHKDSPCGDTQ--------LECYRCGS---- 160

  Fly   392 TVTFEIHTQFLGEAIEKYVLNFDLLKVRR-VFTVIVCKTK-EEVA---------EAEKRMIAAEA 445
                            |.|.|...:..:: ...||:|:|. ..:|         |..|.:||.:.
 Worm   161 ----------------KNVFNLGFIPGKKDQVVVIICRTPCASIAFQNDDNWSPEDWKSVIAEKQ 209

  Fly   446 LMAPGRNSQERSRFYANQVWCNKVDVIPGQQIVTKRRFVALRLGCFE---------VPKELRQIC 501
            |::                |.  |:|...:|:...|:..|.:....|         ...:|.:..
 Worm   210 LLS----------------WI--VNVPSEEQVARARKITATQAVRMEELWRDHPEATVDDLNKPG 256

  Fly   502 LTSERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNFRNYDR------DRA--- 557
            |..|.....::.::.|:           |...||.|:.:|        ..|||      .:|
 Worm   257 LDREPDHVQLRYVDAHH-----------YSKVFRPLVAIE--------AEYDRRVKESASQAVGT 302

  Fly   558 ----HFLRDGEFLTLQIENLAERRPSLVIGDTLRVINPWSDPDSQTTK----------------- 601
                ..||........:...|:....|..||.||:.:..:...|:.||
 Worm   303 VRWEQGLRQSVLAFFHLPQFADGVMKLAKGDELRLKHSQTVDGSEWTKIGSVFKIPDNHGDEVGI 367

  Fly   602 SYEGIIHK-VLFDRILLKFHSSFQEKYNGEDYRLEFYFSRYSFRKQHHAIS-------------- 651
            ...|.:.| |:..||:               :.::..::..:|.:|:.|::
 Worm   368 EIRGAVDKSVMESRIM---------------FTVDVVWNATTFERQYKALAALLNDSKAISPYLY 417

  Fly   652 -KIVGVMGED----FLFPSKVTKRENPQLDVYMKDDDMYLYDSKLEWYNQSLNSIQKRAVFNILR 711
             |::|...|:    |..|.:::....|:                       |||.|.:||..:|.
 Worm   418 QKLLGHPAEEMMLKFDLPRRLSVAGLPE-----------------------LNSSQMQAVKQVLT 459

  Fly   712 GEAENIPYVLFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALLQGD 776
            ....    ::.||||:|||:.....:..||:...| .:||.:|||.:.|.:.:::  .|..|:
 Worm   460 RPLS----LIQGPPGTGKTVVSATIVYHLVQKTEG-NVLVCSPSNIAVDHLAEKI--HKTGLK-- 515

  Fly   777 FIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDKMMV---TESG-LKLR-----CQAKFIGT 832
            .:||.:.::...:...|.:   .....:..:|..|.:.::   .|:| |:.:     .|.|.:..
 Worm   516 VVRLCARSREHSETTVPYL---TLQHQLKVMGGAELQKLIQLKDEAGELEFKDDLRYMQLKRVKE 577

  Fly   833 HRITIST---CTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQ 894
            |.:..:.   |.|..:.............||.||:.|.||||.:|.|:...:   |:||.||..|
 Worm   578 HELLAAADVICCTCSSAADARLSKIRTRTVLIDESTQATEPEILVSIMRGVR---QLVLVGDHCQ 639

  Fly   895 LQSIVTSRIASKMGFSISFLER--LLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSI 957
            |..:|..:.|:..|.|.|..||  ||...|:|..:|                   ||..|.:...
 Worm   640 LGPVVICKKAAIAGLSQSLFERLVLLGIRPFRLQVQ-------------------YRMHPVLSEF 685

  Fly   958 YSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAH-GTFFYGIIGENRQNNDSPSWFN 1021
            .|.:|||..|...::|.|          |.:...:...|:.: ..||:...|....:....|:.|
 Worm   686 PSNVFYDGSLQNGVTEND----------RHMTGVDWHWPKPNKPAFFWHCSGSEELSASGTSFLN 740

  Fly  1022 PQEVREVFLMTIALYRANVTADQIGIITPYQKQVKMLRSMFI------GT-------DVVMPKIG 1073
            ..|...|..:...|.:|.|...|||:||||:.|    ||..:      ||       :|   :|.
 Worm   741 RTEAANVEKLVSKLIKAGVQPHQIGVITPYEGQ----RSFIVNYMHTQGTLNSKLYENV---EIA 798

  Fly  1074 SVEEFQGQERDIILISTVRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVD 1138
            ||:.|||:|:|.|:::.|||::.:       .:||:...:|||||::||:..:::.||..:||..
 Worm   799 SVDAFQGREKDYIIVTCVRSNDIL-------GIGFLSDPRRLNVAITRAKYGLVLVGNAKVLARH 856

  Fly  1139 ECWRQLI-LFCVKNNAYFG---------CDLPQMVINQKDEV 1170
            :.|.:|| .:..|...|.|         ..||:..|..|:.:
 Worm   857 DLWHELINHYKSKEMLYEGPINALKPLNLALPKATIRTKNNI 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	57/215 (27%)
		AAA_19	720..768	CDD:289986	16/47 (34%)
		DNA2	<840..1155	CDD:224037	96/331 (29%)
		UvrD_C_2	909..1132	CDD:304668	66/238 (28%)
smg-2	NP_490829.1	UPF1_Zn_bind	93..243	CDD:286500	35/220 (16%)
		DNA2	117..874	CDD:224037	202/942 (21%)
		AAA_19	452..>509	CDD:289986	19/61 (31%)
		AAA_12	654..851	CDD:289832	67/239 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810