DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment armi and mov10

DIOPT Version :9

Sequence 1:	NP_001014556.1	Gene:	armi / 38427	FlyBaseID:	FBgn0041164	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	XP_002932163.1	Gene:	mov10 / 100491926	XenbaseID:	XB-GENE-483538	Length:	972	Species:	Xenopus tropicalis

Alignment Length:	995	Identity:	293/995 - (29%)
Similarity:	449/995 - (45%)	Gaps:	195/995 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 QYSKFTRRAIKITPLEKNFGATKLTQQSSMGSSGSGKAVTVTGVNRFITAELWQKESVSLKLTNN 354
            |..||..:.:.   |...:.|.:..|.....:|..|.: |.|...||..   |.|.........|
Frog    50 QLKKFLSKTVS---LPDQYLAIRKDQAQHAKASADGSS-TGTQAQRFTE---WMKRRTEFISDKN 107

  Fly   355 LNRTLRLESITVCND---SESQLSVVSPLESKEISSGSEITVTFEIHTQFLGEAIEKYVL-NFDL 415
                    .|::.::   |:.::....|||.::|         |.|..|  .::.|..:. .:.:
Frog   108 --------GISISSEYDLSDGRIRFHLPLEEEKI---------FPIIIQ--NKSSESVIFTQYKV 153

  Fly   416 LKVRRVFTVIVCKTKEEVAEAEKRMIAAEAL-MAPG--------------------------RNS 453
            |:..|:|:.          |.|.::..::.: :|||                          |:|
Frog   154 LRKMRIFSF----------EDEYKVSLSKPIKLAPGDEYEIKVYSCTAHYGYFPITLVFEFRRDS 208

  Fly   454 QERS----RF---YANQVWCNKV----------------------DVIPGQQIVTKRRFVALRLG 489
            ...|    ||   .:|.....::                      |..|.:..:.......:.||
Frog   209 NSPSFHIGRFLSAVSNSKLAERLGPTSKYIPFQRNFRKPIKRIEDDGFPPESSLNYELEREIPLG 273

  Fly   490 CFEVPKELRQ-----ICLTSERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNF 549
            .|..|..||.     :...|............|...|...|:...|..:|.||:|||||:..::.
Frog   274 DFTPPHNLRSDIINGLFANSGSTTSSSSVGNDHRDLLASSLAFSNYSKKFHLLMHLEEIQMELDI 338

  Fly   550 RNYDRD---RAHFLRDGEFLTLQIENLAERRPSLVIGDTLRVINPWSDPDSQT-TKSYEGIIHKV 610
            |.|||.   ..|..||...|.|.:..:||.|||::.||.|.|  ..||...:. ..||:|.:|.|
Frog   339 RRYDRTDQLMEHDPRDKRLLILNVPGVAENRPSVLRGDHLFV--TLSDERGKPGIISYKGYVHGV 401

  Fly   611 LFDRILLKFHSSFQEKY-NGEDYRLEFYFSRYSFRKQHHAISKIVGVMGEDFLFPSK-----VTK 669
            ..:|:.|.|..:...:: ||..:.:.|.|:|...:.||.|::.......:..|||..     :|.
Frog   402 ELERVKLGFSQNLLRRFLNGLYFDVTFTFNRLPLKIQHRAVNVAKDKNLDQILFPEASHGKCITD 466

  Fly   670 RENPQLDVYMKDDDMYLYDSKLEWYNQSLNSIQKRAVFNILRGEAENIPYVLFGPPGSGKTMTLI 734
            .:.           :.|||..||     .|..|..||..||.|.:...||::|||||:|||:||:
Frog   467 SQR-----------LILYDRILE-----SNPEQYNAVKQILSGISRPAPYLIFGPPGTGKTVTLV 515

  Fly   735 ETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALLQGDFIRLVSYNQVEKDLIPPEIMSYC 799
            |.:.|:|:.:|...:|...||||::||:.:|||  |.|.||...|:::.::..:.:  ||.:..|
Frog   516 EAIKQVVKCIPNCHVLACAPSNSASDLLCERLI--KHLDQGQIYRIIASSRDFRTV--PENIKPC 576

  Fly   800 ATSDVGAVGSCEDK-MMVTESGLKLRCQAKFIGTHRITISTCTTLGNFLQLGFPAGHFTHVLFDE 863
            ...|       :|| ..|..|       ..::..:::.|:|..|.|......||.|||:||..||
Frog   577 CNWD-------KDKESFVFPS-------KHYLKNYKVIITTLVTAGRLASANFPRGHFSHVFIDE 627

  Fly   864 AGQCTEPETMVPIVMLTKKR--------SQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLER 920
            ||...|||.:..|..:....        .|:||:|||:||..|:.|.||.:.|..||.||||:.:
Frog   628 AGHAVEPECVTAIAGILDAMDPENNVDGGQLVLAGDPKQLGPILRSPIAIEHGLGISLLERLMTQ 692

  Fly   921 SP-YRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRESRLLSK 984
            :. |||      .:..|:|..:||||.|||:.|||:.|.:.||||:||.....|       :.||
Frog   693 NDLYRK------VNDCYDPKFVTKLLRNYRSHPSILKIPNELFYDNELKVAADE-------MASK 744

  Fly   985 LRCVFES--EKDIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFLMTIALYR-------ANV 1040
            ..|.:|.  :|..|    ..|:|:.|::.:..:|||:||..|:.|:.:...||:.       |.:
Frog   745 SYCNWEKLPQKGFP----IIFHGVHGKDEREGNSPSFFNVNEIEELLIYLKALFETQGKKCLAKI 805

  Fly  1041 TADQIGIITPYQKQVKMLRSMFIGTDVVMP-----KIGSVEEFQGQERDIILISTVRSSEEILRM 1100
            ...:||||:||:|||:.:|.........:|     |:|||||||||||.:|||||||||::.::.
Frog   806 APKEIGIISPYRKQVEKIRQAIKSELYAVPGIAELKVGSVEEFQGQERKVILISTVRSSQDYVKF 870

  Fly  1101 DARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLILFCVKNNAYFGCDLPQMVIN 1165
            |..|||||::..||.||||:||:|::|:.|||.:|..|..|.:.:.:|..|.:..|..|
Frog   871 DESFSLGFLKNPKRFNVAVTRAKALLILIGNPRILNKDPNWSKFLKYCSDNGSCTGFPL------ 929

  Fly  1166 QKDEVPVCLETFVPSLNTTD 1185
             :|.....:|..:..|:..|
Frog   930 -EDVFDSGIEDLLADLDIND 948

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_001014556.1	AAA_11	698..902	CDD:289831	74/212 (35%)
		AAA_19	720..768	CDD:289986	23/47 (49%)
		DNA2	<840..1155	CDD:224037	134/337 (40%)
		UvrD_C_2	909..1132	CDD:304668	97/237 (41%)
mov10	XP_002932163.1	DEXXQc_Helz-like	478..716	CDD:350796	95/266 (36%)
mov10	XP_002932163.1	SF1_C_Upf1	717..918	CDD:350195	84/211 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	155	1.000	Domainoid score	I4173
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	1	1.000	-	-		otm49238
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1732
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010