Protein Alignment sty and SPRY4

DIOPT Version :9

• Sequence 1: NP_523902.2
• Gene: sty / 38424
• FlyBaseID: FBgn0014388
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_112226.2
• Gene: SPRY4 / 81848
• HGNCID: 15533
• Length: 322
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 93/338 - (27%)
• Similarity: 148/338 - (43%)
• Gaps: 76/338 - (22%)

  Fly   180 PPASPVTLAQPRPESERLTNEYVDTPLQHATRSQHPAGQQDNGQTTTHHL---------LLL--- 232
            |...|:..:.|...:..:....:|:.:.| :|.|||.......|..|.|:         |.|
Human    23 PMEPPIPQSAPLTPNSVMVQPLLDSRMSH-SRLQHPLTILPIDQVKTSHVENDYIDNPSLALTTG 86

  Fly   233 PQRNQHLHLQQHQQHLQQQQQQQQQQQQQQHLQHQQNQQHARLATTTQATSVGSDHTDGLLHSHL 297
            |:|.:.          ...:......:..|.:.|.......|.::.:.::|..||       ..|
Human    87 PKRTRG----------GAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSD-------QRL 134

  Fly   298 QNSTTKPPASKQPAPPRLGMGLGLGLGLGLNQP-IITKQPTPATQKERMHALEELLQPGGAGGNG 361
            .:....||.:.|.:|..:.:           || ::..||....
Human   135 LDHMAPPPVADQASPRAVRI-----------QPKVVHCQPLDLK--------------------- 167

  Fly   362 GPLVMAGDPSLLNP--IVCPRCGRCRCEQCQSPRPLPQTWVCNKTCLCSAESVIDYASCLCCAKA 424
            ||.|    |..|:.  ::|..||:|:|::|.|||.||..||||:.|||||:::::|.:|:|..:.
Human   168 GPAV----PPELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQG 228

  Fly   425 LFYHCARDNDLDCDDGNGTPCVDNPCSCGPYKRTQRWGWLGALSIFLPCLWFYWPMRGCMKLCEK 489
            :||||..::    |:|:   |.|:||||.......||.::||||:.||||..|.|..||:||.::
Human   229 IFYHCTNED----DEGS---CADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQR 286

  Fly   490 CYGRFAGRGCRCQ 502
            .|.|....||||:
Human   287 GYDRLRRPGCRCK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sty	NP_523902.2	Sprouty	384..488	CDD:282994	48/103 (47%)
SPRY4	NP_112226.2	Sprouty	188..285	CDD:282994	48/103 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144942
Domainoid	1	1.000	148	1.000	Domainoid score	I4467
eggNOG	1	0.900	-	-		E1_2CAWB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3918
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1157681at2759
OrthoFinder	1	1.000	-	-		FOG0001173
OrthoInspector	1	1.000	-	-		otm41854
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12365
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4768
SonicParanoid	1	1.000	-	-		X723
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.890