DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sty and crm-1

DIOPT Version :9

Sequence 1:	NP_523902.2	Gene:	sty / 38424	FlyBaseID:	FBgn0014388	Length:	589	Species:	Drosophila melanogaster
Sequence 2:	NP_741616.2	Gene:	crm-1 / 179439	WormBaseID:	WBGene00007103	Length:	966	Species:	Caenorhabditis elegans

Alignment Length:	125	Identity:	34/125 - (27%)
Similarity:	48/125 - (38%)	Gaps:	30/125 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 KERMH--ALEELLQPGGAGGNGGPLVM-AGDPS-----LLNPI---VCPRCGRCRCEQCQSPRPL 395
            |||||  .|:.:.          |||. .|.||     .::|.   .||..|.|.|:|   .:.:
Worm    89 KERMHDDCLKAIC----------PLVFHKGCPSDSQLITVSPAPGNCCPPPGSCHCDQ---KKCV 140

  Fly   396 PQTWVCNK-TCLCSAESVIDYASCLCCAKALFYHCARDNDLDCDDGNGTPCVDNPCSCGP 454
            |....|.| ..|...|...|... .|||   :|.|.: .:..|::.:..|...:...|.|
Worm   141 PSVPTCTKEERLVMVEKGSDIPG-KCCA---YYECHK-KEKKCENVHCPPMFQDEEECPP 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sty	NP_523902.2	Sprouty	384..488	CDD:282994	18/72 (25%)
crm-1	NP_741616.2	IGFBP	28..76	CDD:278641
		VWC	263..319	CDD:302663
		VWC	333..377	CDD:302663
		VWC	607..658	CDD:302663
		VWC	681..734	CDD:302663
		VWC	744..797	CDD:302663
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S2
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950