Protein Alignment sty and SPRY1

DIOPT Version :9

• Sequence 1: NP_523902.2
• Gene: sty / 38424
• FlyBaseID: FBgn0014388
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_001244967.1
• Gene: SPRY1 / 10252
• HGNCID: 11269
• Length: 319
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 98/326 - (30%)
• Similarity: 152/326 - (46%)
• Gaps: 63/326 - (19%)

  Fly   179 QPPASPVTLAQPRPESERLTNEYVDTPLQHATRSQHPAGQQDNGQTTTHHLLLLPQRNQHLHLQQ 243
            ||.|   .|:..:.::.|.:|||.:.|......:...|.:|:..: .||.::.:...|.:.|
Human    34 QPTA---ILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKHE-RTHEIIPINVNNNYEH--- 91

  Fly   244 HQQHLQQQQQQQQQQQQQQHLQHQQNQQHARLATTTQATSVGSDHTDGLLHSHLQNSTTKPPASK 308
                           :...||.|.....:||....:::||.||..:.|      .||:.   :|:
Human    92 ---------------RHTSHLGHAVLPSNARGPILSRSTSTGSAASSG------SNSSA---SSE 132

  Fly   309 QPAPPRLGMGLGLGLGLGLNQPIITKQPTPATQKERMHALE--ELLQPGGAGGNGGPLVMAGDPS 371
            |            || ||.:.|   .:|.|..:.||....:  :|:.....|.....|..
Human   133 Q------------GL-LGRSPP---TRPVPGHRSERAIRTQPKQLIVDDLKGSLKEDLTQ----- 176

  Fly   372 LLNPIVCPRCGRCRCEQCQSPRPLPQTWVCNKTCLCSAESVIDYASCLCCAKALFYHCARDNDLD 436
              :..:|.:||:|:|.:|.:||.||....||:.|||||||:::|.:|:|..|.:||||:.|::
Human   177 --HKFICEQCGKCKCGECTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIFYHCSNDDE-- 237

  Fly   437 CDDGNGTPCVDNPCSCGPYKRTQRWGWLGALSIFLPCLWFYWPMRGCMKLCEKCYGRFAGRGCRC 501
                 |....||||||.......|:..:||:|:|||||..|.|.:||:|||.:||......||||
Human   238 -----GDSYSDNPCSCSQSHCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDWIHRPGCRC 297

  Fly   502 Q 502
            :
Human   298 K 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sty	NP_523902.2	Sprouty	384..488	CDD:282994	47/103 (46%)
SPRY1	NP_001244967.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..78		3/24 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	100..160		20/84 (24%)
		Sprouty	187..284	CDD:368340	47/103 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144943
Domainoid	1	1.000	148	1.000	Domainoid score	I4467
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3918
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1157681at2759
OrthoFinder	1	1.000	-	-		FOG0001173
OrthoInspector	1	1.000	-	-		otm41854
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12365
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X723
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.960