Protein Alignment sty and SPRY3

DIOPT Version :9

• Sequence 1: NP_523902.2
• Gene: sty / 38424
• FlyBaseID: FBgn0014388
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_001291919.1
• Gene: SPRY3 / 10251
• HGNCID: 11271
• Length: 288
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 102/310 - (32%)
• Similarity: 137/310 - (44%)
• Gaps: 67/310 - (21%)

  Fly   194 SERLTNEYVDTPLQHATRSQHPAGQQDNGQTTTHHLLLLPQRNQHLHLQQHQQHLQQQQQQ-QQQ 257
            |...:|:||:.|         ||..:   |..:...|::........|......|.:...| .|.
Human    20 STHASNDYVERP---------PAPCK---QALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQL 72

  Fly   258 QQQQQHLQHQQNQQHARLATTTQATSVGSDHTDGLLHSHLQNSTTKPPASKQPAPPRLGMGLGLG 322
            |...|||      ..:.:|::...::..||..  ||            ||..|:|.
Human    73 QPLPQHL------SQSSIASSMSHSTTASDQR--LL------------ASITPSPS--------- 108

  Fly   323 LGLGLNQPIITKQPTPATQKERMHALEELLQPGGAGGNGGPLVMAGDPSLLNPIVCPRCGRCRCE 387
                 .|.||..||......:...||:           |.....||.|| .:..:|..||||:|.
Human   109 -----GQSIIRTQPGAGVHPKADGALK-----------GEAEQSAGHPS-EHLFICEECGRCKCV 156

  Fly   388 QCQSPRPLPQTWVCNKTCLCSAESVIDYASCLCCAKALFYHCARDNDLDCDDGNGTPCVDNPCSC 452
            .|.:.||||..|:||:.|||||||::||.:||||.|.|||||:.|     |:.|   |.|.||||
Human   157 PCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTD-----DEDN---CADEPCSC 213

  Fly   453 GPYKRTQRWGWLGALSIFLPCLWFYWPMRGCMKLCEKCYGRFAGRGCRCQ 502
            ||.....||..:..:|:|||||..|.|.|||:.||::.|......||||:
Human   214 GPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRCK 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sty	NP_523902.2	Sprouty	384..488	CDD:282994	54/103 (52%)
SPRY3	NP_001291919.1	Sprouty	152..253	CDD:398746	56/108 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144944
Domainoid	1	1.000	148	1.000	Domainoid score	I4467
eggNOG	1	0.900	-	-		E1_2CAWB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3918
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1157681at2759
OrthoFinder	1	1.000	-	-		FOG0001173
OrthoInspector	1	1.000	-	-		otm41854
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12365
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X723
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.860