DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ids and Arsi

DIOPT Version :9

Sequence 1:	NP_647814.1	Gene:	Ids / 38423	FlyBaseID:	FBgn0035445	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001033588.1	Gene:	Arsi / 545260	MGIID:	2670959	Length:	573	Species:	Mus musculus

Alignment Length:	420	Identity:	88/420 - (20%)
Similarity:	139/420 - (33%)	Gaps:	159/420 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AAAPPRRPNVVMVIFDDL-RPVIGAYGDTLASTPYLDNFARGSHIFTRVYSQQSLCAPSRNSLLT 81
            :.|||:.|:::.::.||. ...:|.:|..: .||.||..| ...:....|..|.:|.|||:.|||
Mouse    40 SVAPPQPPHIIFILTDDQGYHDVGYHGSDI-ETPTLDRLA-AEGVKLENYYIQPICTPSRSQLLT 102

  Fly    82 G---------------RRPDTLHLYDFYSYWRTFTGNFTTLPQYFKEHGYYTYSCGKVFHPGLSS 131
            |               |:|:.|.|            :..||||..:|.||.|:..|| :|.|
Mouse   103 GRYQIHTGLQHSIIRPRQPNCLPL------------DQVTLPQKLQEAGYSTHMVGK-WHLG--- 151

  Fly   132 NNTDDYPLSWSAPAFRPRTEQFMNSPVCPDKEGI------LRKNL------------ICPVELQT 178
                                 |......|.:.|.      |..|:            :|..:|.
Mouse   152 ---------------------FYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLH- 194

  Fly   179 QPYKTLPDIESVAEAL------RFVGSRSRH------SQEPFFLAMGFHKPHINFRFPRQFLSRF 231
                   :.||||..|      .....|:.|      .|.|.||.:.|...|...:.||::|.|:
Mouse   195 -------EGESVAWGLSGQYSTMLYAQRASHILASHNPQNPLFLYVAFQAVHTPLQSPREYLYRY 252

  Fly   232 NLSQFYNYTEDSLKPPDMPAVAWNPYTDVRARDDFKHSNISFPYGPISPLQAAQIRQSYYASVSY 296
            ...                                  .|::              |:.|.|.|:.
Mouse   253 RTM----------------------------------GNVA--------------RRKYAAMVTC 269

  Fly   297 VDDLFGKLIGGLD----LDETVVVALGDHG---------WSLGEHAEWAKYSNFEVALRVPLIIR 348
            :|:....:...|.    .:.:|::...|:|         |.|    ...|.:.:|..:|....:.
Mouse   270 MDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPL----RGRKGTYWEGGVRGLGFVH 330

  Fly   349 SPQFPVAQTKYYHGITELLDVFPTLVDLAG 378
            ||... .:.:....:..:.|.:||||.|||
Mouse   331 SPLLK-KKRRTSRALVHITDWYPTLVGLAG 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ids	NP_647814.1	AslA	21..509	CDD:225661	87/417 (21%)
Ids	NP_647814.1	iduronate-2-sulfatase	24..495	CDD:293754	85/414 (21%)
Arsi	NP_001033588.1	AslA	47..492	CDD:225661	85/413 (21%)
		4-S	47..478	CDD:293753	85/413 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	515..550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900