Protein Alignment Ids and ARSL

DIOPT Version :9

• Sequence 1: NP_647814.1
• Gene: Ids / 38423
• FlyBaseID: FBgn0035445
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001269557.1
• Gene: ARSL / 415
• HGNCID: 719
• Length: 614
• Species: Homo sapiens
• Alignment Length: 598
• Identity: 143/598 - (23%)
• Similarity: 214/598 - (35%)
• Gaps: 156/598 - (26%)

  Fly     5 RLLLSLMMPVLLDAA------APPRRPNVVMVIFDDLR-PVIGAYGDTLASTPYLDNFARGSHIF 62
            |..|..|:.|||..|      ....|||:::::.|||. ..||.||:....||.:|..|......
Human    37 RSWLPAMLAVLLSLAPSASSDISASRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAEDGVKL 101

  Fly    63 TRVYSQQSLCAPSRNSLLTGRRPDTLHLYDFYSY----WRTFTG----NFTTLPQYFKEHGYYTY 119
            |:..|..|||.|||.:.||||.|....:.....|    |...:|    |.||..:..||.||.|.
Human   102 TQHISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYATG 166

  Fly   120 SCGKVFHPGLSSNNTDDY---------------PLS-------WSAPAFRPRTEQFMNSPVCPDK 162
            ..|| :|.||:..:..|:               |.|       |.....|...||.:|  .....
Human   167 LIGK-WHLGLNCESASDHCHHPLHHGFDHFYGMPFSLMGDCARWELSEKRVNLEQKLN--FLFQV 228

  Fly   163 EGILRKNLICPVELQTQPYKTLPDIESVAEAL------RFVGSRSRHSQEPFFLAMGFHKPHINF 221
            ..::...|:........|...:|.|.|...|:      .|||:...|:.  .||.    :.|...
Human   229 LALVALTLVAGKLTHLIPVSWMPVIWSALSAVLLLASSYFVGALIVHAD--CFLM----RNHTIT 287

  Fly   222 RFPRQF--LSRFNLSQFYNYTEDSLKPPDMPAVAWNPYTDVRARDDFKHSNISFPYGPISPLQAA 284
            ..|..|  .:...|.:..::.:.:...|.:..|:            |.|.:|  |...:......
Human   288 EQPMCFQRTTPLILQEVASFLKRNKHGPFLLFVS------------FLHVHI--PLITMENFLGK 338

  Fly   285 QIRQSYYASVSYVDDLFGKLIGGLDLD----ETVVVALGDHGWSLGEHAEWAKY----------- 334
            .:...|..:|..:|.:.|:::..||::    .|::....|||.||.......:|
Human   339 SLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGK 403

  Fly   335 --SNFEVALRVPLIIRSPQFPVAQTKYYHGI----------TELLDVFPTLVDLAG--LPKLDKC 385
              ..:|..:|||.|.|.|           |:          |.|:|||||:|.|||  :|: |:.
Human   404 GMGGWEGGIRVPGIFRWP-----------GVLPAGRVIGEPTSLMDVFPTVVRLAGGEVPQ-DRV 456

  Fly   386 QSSQELTCGEGKSLYHQLMGLGRADEHVALSQYPRPGMLPTKHPNSDKPKLRNIKIMGYSLRTDI 450
            .        :|:.|...|:|..:..:|..|..|....:...:....|
Human   457 I--------DGQDLLPLLLGTAQHSDHEFLMHYCERFLHAARWHQRD------------------ 495

  Fly   451 YRYTMW-VRFHAQNF---------SRDWHDVYGEE--------LYDHRLDSGEELNLMPL--PQF 495
             |.||| |.|....|         .|.....:||:        |:|...|..|...|.|.  |.|
Human   496 -RGTMWKVHFVTPVFQPEGAGACYGRKVCPCFGEKVVHHDPPLLFDLSRDPSETHILTPASEPVF 559

  Fly   496 DDVRQRLRRRLME 508
            ..|.:|:::.:.|
Human   560 YQVMERVQQAVWE 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ids	NP_647814.1	AslA	21..509	CDD:225661	136/576 (24%)
		iduronate-2-sulfatase	24..495	CDD:293754	132/558 (24%)
ARSL	NP_001269557.1	ALP_like	62..585	CDD:355016	136/573 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810