DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ids and CG32191

DIOPT Version :9

Sequence 1:	NP_647814.1	Gene:	Ids / 38423	FlyBaseID:	FBgn0035445	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster

Alignment Length:	597	Identity:	137/597 - (22%)
Similarity:	213/597 - (35%)	Gaps:	166/597 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ITARLLLSLMMPVLLDAAAPPRRPNVVMVIFDDLR-PVIGAYGDTLASTPYLDNFARGSHIFTRV 65
            ::|.|||..:..|..|.:|..||||:::::.||:. ..:...|.....||.:|..|....:..|:
  Fly     4 LSAFLLLLCLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRL 68

  Fly    66 YSQQSLCAPSRNSLLTGRRP---DTLHLYDFYSYWRTFTGNFTTLPQYFKEHGYYTYSCGKVFHP 127
            |: .::|.|||.:||:||.|   .|.|...........|.|.|.:|:.|||.||.|...|| :|.
  Fly    69 YA-PAMCTPSRGALLSGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGK-WHL 131

  Fly   128 GLS------SNNTDDYPLS-WSA--PAFRPRTEQFMNSPVCPDKEGI-LRKNLICPVELQTQP-- 180
            |.|      :....||... |.|  ..|:.|::.    ||.....|. .|:|:    ||:.:.
  Fly   132 GFSRPEYTPTRRGFDYHFGYWGAYIDYFQRRSKM----PVANYSLGYDFRRNM----ELECRDRG 188

  Fly   181 -YKTLPDIESVAEALRFVGSRSRHSQEPFFLAMGFHKPHINFRFPRQFLSRFNLSQFYNYTEDSL 244
             |.|  |: ..|||.|.:...: ..::|.||.:.                  :|:......:|.|
  Fly   189 VYVT--DL-LTAEAERLIKDHA-DKEQPLFLMLS------------------HLAAHTANEDDPL 231

  Fly   245 KPPDMPAVAWNPYTDVRARDDFKHSNISFPYGPISPLQAAQIRQSYYASVSYVDDLFGKLIGGL- 308
            :.|:              .:..|.|.|..|.           |:.|.|.:|.:|...|::|..|
  Fly   232 QAPE--------------EEIQKFSYIKDPN-----------RRKYAAMISKLDQSVGRIITALS 271

  Fly   309 ---DLDETVVVALGDHG----------------------------------WSLGEHAEWAKYSN 336
               .|:.::|:...|:|                                  ||.|..|..:.:..
  Fly   272 STDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIFRQ 336

  Fly   337 -FEVALRVPLIIRSPQFPVAQTKYYHGITELLDVFPTLVDLAGLPK--------LDKCQSSQELT 392
             ..||..:|.:.|:....:..:....||    |::|.|...|..|.        ||.......|.
  Fly   337 PLYVADWLPTLSRAADIELDSSLKLDGI----DLWPELSGSADAPHVPREILHILDDVWRLSALQ 397

  Fly   393 CGEGKSL--------------YHQLMGLGRADEHVALSQYPRPGMLPTKHPNSDKPKLRNIKIMG 443
            .|:.|.:              |.:|..|...|...|::                   :||.....
  Fly   398 MGQWKYVNGTTASGRYDSVLTYRELDDLDPRDSRYAVT-------------------VRNSATSR 443

  Fly   444 YSLRTDIYRYTM--------WVRFHAQNFSRDWHDVYGEELYDHRLDSGEELNLMPLPQFDDVRQ 500
            ...|.|:.|.|.        .......:..|..:.:..|.|||...|..|:.||:...:..||..
  Fly   444 ALSRYDLRRLTQQRISLTRRLAAVRCGDLQRSCNPLLEECLYDILSDPCEQNNLVYSERHSDVLT 508

  Fly   501 RLRRRLMEMVGS 512
            .||||:.|:..|
  Fly   509 ALRRRVQELRAS 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ids	NP_647814.1	AslA	21..509	CDD:225661	128/573 (22%)
Ids	NP_647814.1	iduronate-2-sulfatase	24..495	CDD:293754	121/556 (22%)
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	113/514 (22%)
		4-S	27..408	CDD:293753	100/441 (23%)
		DUF4976	<478..540	CDD:303608	16/43 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466506
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740