DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ids and Gns

DIOPT Version :9

Sequence 1:	NP_647814.1	Gene:	Ids / 38423	FlyBaseID:	FBgn0035445	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	XP_006241458.1	Gene:	Gns / 299825	RGDID:	1305877	Length:	544	Species:	Rattus norvegicus

Alignment Length:	472	Identity:	120/472 - (25%)
Similarity:	186/472 - (39%)	Gaps:	127/472 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ARLLLSLMMPVL---LDAAAPPRRPNVVMVIFDD-------------LRPVIGAYGDTLASTPYL 52
            :||...|::|:|   |......|||||::::.||             .:.:||..|.|
  Rat    15 SRLPALLLLPLLSGCLGLVGAARRPNVLLLLTDDQDAELGGMTPLKKTKALIGEKGMT------- 72

  Fly    53 DNFARGSHIFTRVYSQQSLCAPSRNSLLTGRRPDTLHLYDFYSYWRTFTGNFT-----------T 106
                     |:..|...:||.|||.|:|||:.|...|:.:     .|..||.:           |
  Rat    73 ---------FSSAYVPSALCCPSRASILTGKYPHNHHVVN-----NTLEGNCSSKSWQKIQEPYT 123

  Fly   107 LPQYFK-EHGYYTYSCGKVF--HPGLSSNNTDDYPLSWSAPAFRPRTEQFMNSPVCPDKEGILRK 168
            .|...| ..||.|:..||..  :....:...:..||.||......:..::.|..:  ...|..|:
  Rat   124 FPAILKLVCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTL--SINGKARR 186

  Fly   169 NLICPVELQTQPYKT--LPDIESVAEALRFVGSRSRHSQEPFFLAMGFHKPHINF--------RF 223
            :    .|..:..|.|  |.::     :|.|:..:|  :.||||:.:....||..:        .|
  Rat   187 H----GENYSVDYLTDVLANL-----SLDFLDYKS--NSEPFFMMISTPAPHSPWTAAPQYQKAF 240

  Fly   224 PRQFLSR---FNLSQFYNYTEDSLKPPDMPAVAWNPYTDVR-ARDDFKHSNISFPYGPISPLQAA 284
            |.....|   ||:.                  ..|.:..:| |:....:|:|.|       |..|
  Rat   241 PNVIAPRNKNFNIH------------------GTNKHWLIRQAKTPMTNSSIKF-------LDDA 280

  Fly   285 QIRQSYYASVSYVDDLFGKLIGGLD----LDETVVVALGDHGWSLGEHA-EWAKYSNFEVALRVP 344
             .|:.:...:| ||||..||:..||    ||.|.:....|:|:..|:.: ...|...:|..::||
  Rat   281 -FRRRWQTLLS-VDDLVEKLVKRLDSTGELDNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVP 343

  Fly   345 LIIRSPQFPVAQTKYYHGITELLDVFPTLVDLAGLPKLDKCQSSQELTCGEGKSLYHQLMGLG-- 407
            |::|.|.....||...  :...:|:.||::||||. .|:|.|.       :|.||...|.|.|
  Rat   344 LLVRGPGIKPNQTSKM--LVSNIDLGPTILDLAGY-DLNKTQM-------DGTSLLPILKGDGNL 398

  Fly   408 --RADEHVALSQYPRPG 422
              |:|   .|.:|...|
  Rat   399 TWRSD---VLVEYQGEG 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ids	NP_647814.1	AslA	21..509	CDD:225661	114/452 (25%)
Ids	NP_647814.1	iduronate-2-sulfatase	24..495	CDD:293754	113/449 (25%)
Gns	XP_006241458.1	G6S	38..487	CDD:293766	113/449 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810