DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ids and Galns

DIOPT Version :9

Sequence 1:	NP_647814.1	Gene:	Ids / 38423	FlyBaseID:	FBgn0035445	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	XP_017456734.1	Gene:	Galns / 292073	RGDID:	1565391	Length:	567	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	110/485 - (22%)
Similarity:	162/485 - (33%)	Gaps:	158/485 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLSLMMPVL-LDAAAPPRRPNVVM--------------------VIFDDLRPVIGAYGDTLASTP 50
            |.|:.:|:| .....||..|....                    :...|..|...|.|...:.|
  Rat    44 LFSVALPLLSFGRQGPPHTPKGTAARLGLSLAWLCSRSLDCHDGLFHSDQGPAATAAGTECSRT- 107

  Fly    51 YLDNFARGSHIFTRVYSQQSLCAP----SRNSLLTGRRP-------DTLHLYDFYSYWRTFTG-- 102
                      :..|..:....||.    ||.:|||||.|       ...|..:.|:......|
  Rat   108 ----------LGCRCSAAPQHCATAHGRSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIMGGIP 162

  Fly   103 -NFTTLPQYFKEHGYYTYSCGK-------VFHPGLSSNNTDDYPLSWSAP--AFRPRTEQFM-NS 156
             :...||:..|:.||.....||       .|||  ..:..|::   :.:|  .|.|...:.. |.
  Rat   163 NSEHLLPELLKKAGYTNKIVGKWHLGHRPQFHP--LKHGFDEW---FGSPNCHFGPYDNKVKPNI 222

  Fly   157 PVCPDKEGILRKNLICPVELQ------TQPYKTLPDIESVAEALRFVGSRSRHS-QEPFFLAMGF 214
            ||..|.|.:.|.....|:.|:      ||.|        :.|||.|:  |::|: |.||||....
  Rat   223 PVYRDWEMVGRFYEEFPINLKTGEANLTQLY--------LQEALDFI--RTQHARQSPFFLYWAI 277

  Fly   215 HKPHINFRFPRQFLSRFNLSQFYNYTEDSLKPPDMPAVAWNPYTDVRARDDFKHSNISFPYGPIS 279
            ...|......:|||.                            |.:|.|           ||.
  Rat   278 DATHAPVYASKQFLG----------------------------TSLRGR-----------YGD-- 301

  Fly   280 PLQAAQIRQSYYASVSYVDDLFGKLIGGLD----LDETVVVALGDHGWSL-------GEHAEW-- 331
                         :|..:||..||::..|.    ...|.|....|:|.:|       |.:..:
  Rat   302 -------------AVREIDDSVGKILSLLQNLGISKNTFVFFTSDNGAALISAPKEGGSNGPFLC 353

  Fly   332 AKYSNFEVALRVPLIIRSPQFPVAQTKYYHGITELLDVFPTLVDLAGL-PKLDKCQSSQEL--TC 393
            .|.:.||..:|.|.|...|.. :|..:..|.:..::|:|.|.:.|||| |..|:.....:|  |.
  Rat   354 GKQTTFEGGMREPAIAWWPGH-IAAGQVSHQLGSIMDLFTTSLSLAGLKPPSDRVIDGLDLLPTM 417

  Fly   394 GEGKSL-----YHQLMGLGRADEHVALSQY 418
            .:|..:     |::    |.....|.|.||
  Rat   418 LQGHIIDRPIFYYR----GNTLMAVTLGQY 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ids	NP_647814.1	AslA	21..509	CDD:225661	106/470 (23%)
Ids	NP_647814.1	iduronate-2-sulfatase	24..495	CDD:293754	104/467 (22%)
Galns	XP_017456734.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810