Protein Alignment Ids and ARSK

DIOPT Version :9

• Sequence 1: NP_647814.1
• Gene: Ids / 38423
• FlyBaseID: FBgn0035445
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_937793.1
• Gene: ARSK / 153642
• HGNCID: 25239
• Length: 536
• Species: Homo sapiens
• Alignment Length: 584
• Identity: 136/584 - (23%)
• Similarity: 236/584 - (40%)
• Gaps: 146/584 - (25%)

  Fly     1 MITARLLLSLMMPVLLDAAAPPRR-----PNVVMVIFDDLRPVIGAY-GDTLASTPYLDNF--AR 57
            ::...::.:|.:.||...|...||     ||||:|:.|.....:..: |..:...|:: ||  .|
Human     3 LLWVSVVAALALAVLAPGAGEQRRRAAKAPNVVLVVSDSFDGRLTFHPGSQVVKLPFI-NFMKTR 66

  Fly    58 GSHIFTRVYSQQSLCAPSRNSLLTGRRPDTLHLYDFYSYWRTFTG---NFTTLPQYFKEHGYYTY 119
            |:. |...|:...:|.|||.::.:|.   ..||.:   .|..|.|   |:||.....:.|||.|.
Human    67 GTS-FLNAYTNSPICCPSRAAMWSGL---FTHLTE---SWNNFKGLDPNYTTWMDVMERHGYRTQ 124

  Fly   120 SCGKV----FHPGLSSNNTDDYPLSWSAP-AFRPRTEQFMNSPVCPDKEGILRKNLICPVELQTQ 179
            ..||:    .|..: ||..:    :|:.. ||..|            :||....|||   ..:|:
Human   125 KFGKLDYTSGHHSI-SNRVE----AWTRDVAFLLR------------QEGRPMVNLI---RNRTK 169

  Fly   180 PYKTLPDIESVAEALRFVGSRSRHSQEPFFLAMGFHKPH--------INFRFPRQFLSRFNLSQF 236
            ......|.::..:|:.::...:.:..|||.:.:|.:.||        .||.     .|.|:.|.:
Human   170 VRVMERDWQNTDKAVNWLRKEAINYTEPFVIYLGLNLPHPYPSPSSGENFG-----SSTFHTSLY 229

  Fly   237 Y--NYTEDSLKPPDMPAVAWNPYTDVRARDDFKH--SNISFPYGPISPLQAAQIRQSYYASVSYV 297
            :  ..:.|::|.|     .|:|.:::...|.:..  .|.:   |..:..:...||..|||..:..
Human   230 WLEKVSHDAIKIP-----KWSPLSEMHPVDYYSSYTKNCT---GRFTKKEIKNIRAFYYAMCAET 286

  Fly   298 DDLFGKLIGGLD----LDETVVVALGDHGWSLGEHAEWAKYSNFEVALRVPLIIRSPQFPVAQTK 358
            |.:.|::|..|.    |.:|:|:...|||....||.::.|.|.:|.:..|||::..|  .:....
Human   287 DAMLGEIILALHQLDLLQKTIVIYSSDHGELAMEHRQFYKMSMYEASAHVPLLMMGP--GIKAGL 349

  Fly   359 YYHGITELLDVFPTLVDLAGLPKLDKCQSSQELTCGEGKSLYHQLMGLGRADEHVALSQYP---- 419
            ....:..|:|::||::|:||:|      ..|.|:   |.||. .|......:||...:.:|
Human   350 QVSNVVSLVDIYPTMLDIAGIP------LPQNLS---GYSLL-PLSSETFKNEHKVKNLHPPWIL 404

  Fly   420 ----------RPGMLPTKH-------------P-----NSDKPKLRNIKI----MGYSLRTDIY- 451
                      ...||.|.|             |     :||..:|.|:.:    :.|||...::
Human   405 SEFHGCNVNASTYMLRTNHWKYIAYSDGASILPQLFDLSSDPDELTNVAVKFPEITYSLDQKLHS 469

  Fly   452 -----------------RYTMWVRFHAQNFSR-----DWHDVYGEE--LYDHRLDSGEELNLMP 491
                             ::..|.:...||:|.     .||..:.:|  .|::.:|...:.::.|
Human   470 IINYPKVSASVHQYNKEQFIKWKQSIGQNYSNVIANLRWHQDWQKEPRKYENAIDQWLKTHMNP 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ids	NP_647814.1	AslA	21..509	CDD:225661	132/564 (23%)
		iduronate-2-sulfatase	24..495	CDD:293754	131/561 (23%)
ARSK	NP_937793.1	ARSK	32..447	CDD:293781	115/467 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810