Protein Alignment CG12010 and YTA6

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_015251.1
• Gene: YTA6 / 856031
• SGDID: S000005995
• Length: 754
• Species: Saccharomyces cerevisiae
• Alignment Length: 605
• Identity: 149/605 - (24%)
• Similarity: 259/605 - (42%)
• Gaps: 128/605 - (21%)

  Fly   197 FERPME-QLEKLLE---TSKISF------------------SHRFPTTALVVGPVDCGKSGLLSE 239
            :||.:| |.|||:|   ..|:.|                  .||.......:..:   |....:.
Yeast   188 YERDLELQREKLIELKVKEKVEFEVAQKLEEERVKREEEERKHREQAEKKRISTL---KHERKTN 249

  Fly   240 FLRRHSCNCFYITASQVLRSYPGETEEEL--RRIFQAAQTFKEKLRPLLPIVILIEDLEL-LCPS 301
            :..|.|.:.|..::..     .|:.:..|  ||.....:|..|::|  .|:...:|..|: :...
Yeast   250 YKSRASLDNFSSSSKS-----SGKIDNSLIKRRSLDVVRTSGERVR--TPVRKSMEAAEIGMAAQ 307

  Fly   302 TAVADAKNSSNSLRI------SAEL---YKLLDALPRGIICLATSGVPDSLHEHARRRFVREVTI 357
            .|.:..:|.:|..::      |.||   ||....|.:..         |.......|..::..|:
Yeast   308 LAWSQYQNGANHSKVSNNGSHSNELQIRYKPTPPLKKRY---------DYKKPTVNRPIIKSPTL 363

  Fly   358 NMPSEGQRRQLVEHLCEVHELNISQTLLEHIARNTQGYVIADLTLLLRRVQQQLLTKDDFDIEHI 422
            |..:....|.:..:    .:|..|::....::|..:..:.....:|:........:|.
Yeast   364 NRQNSKSSRNIPTN----SKLKASKSNTNKVSRRNEQNLEPSSPVLVSATAVPAESKP------- 417

  Fly   423 FLKSLSQT---QPSASRSTDVR---VSKMTAG---------------------FEVIGGMEALKR 460
             ::|.|.|   :.|||.|.|.|   :.|...|                     :|.|.|:...|.
Yeast   418 -MRSKSGTPDKESSASSSLDSRKEDILKSVQGVDRNACEQILNEILVTDEKVYWEDIAGLRNAKN 481

  Fly   461 TLQVSVLAGIRQSAAFARFGLSLP-KGVLLYGPPGCAKTTVAKCLAKEADMTFIATSAAEVYSPY 524
            :|:.:|:....:...|.  ||..| :|:||:||||..||.:||.:|.|::.||.:.||:.:.|.|
Yeast   482 SLKEAVVYPFLRPDLFK--GLREPVRGMLLFGPPGTGKTMIAKAVATESNSTFFSVSASSLLSKY 544

  Fly   525 VGCAERFISRIFDTARKNAPCLIFLDEIDSLVGRRTVSSGGGGGQVQLRILSTLLTEMNGIVGGG 589
            :|.:|:.:..:|..|:|.:|.:||:|||||::..|:.:.    .:...||.:.||.:.:.:....
Yeast   545 LGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARSDNE----NESSRRIKTELLIQWSSLSSAT 605

  Fly   590 SQ---------QHILVVAATNRPDMIDDALLRPGRFDKLIHVPAPDEKSRLALLKLHSQRMPFHE 645
            :|         ..:||:.|||.|..||||..|  ||.:.:::|.||.::||    .|.:|:...:
Yeast   606 AQSEDRNNTLDSRVLVLGATNLPWAIDDAARR--RFSRKLYIPLPDYETRL----YHLKRLMAKQ 664

  Fly   646 NVFLQE-----IAARTDRYSGADLCNLCNEAAIEAFQ--------RDF-KATEIELQDFEKVLTK 696
            ...||:     |...|:.:||:||.:|..|||:|..:        .|| |...||::||:..|..
Yeast   665 KNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIRDLGDKLMFADFDKIRGIEIKDFQNALLT 729

  Fly   697 QKSSLTQSQIDGYYKFAYRF 716
            .|.|::...:..|.:::.:|
Yeast   730 IKKSVSSESLQKYEEWSSKF 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	136/555 (25%)
YTA6	NP_015251.1	PTZ00108	<158..412	CDD:240271	44/246 (18%)
		RecA-like_VPS4-like	473..645	CDD:410917	60/179 (34%)
		AAA_lid_3	670..714	CDD:465537	13/43 (30%)
		Vps4_C	<718..750	CDD:462762	9/32 (28%)