Protein Alignment CG12010 and PCH2

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_009745.2
• Gene: PCH2 / 852484
• SGDID: S000000390
• Length: 564
• Species: Saccharomyces cerevisiae
• Alignment Length: 476
• Identity: 108/476 - (22%)
• Similarity: 185/476 - (38%)
• Gaps: 106/476 - (22%)

  Fly   237 LSEFLRRHSCNCFYITASQVLRSYPGE-------TEEELRRIFQAAQTFKEKLRPLLPIVILIED 294
            |.|||     |.......:.|.|:|.:       |.:||.|..|.:...|:.  |......||..
Yeast    44 LGEFL-----NLLKAVVKRKLESFPKDRLKTSIITGQELMREGQGSIEIKDP--PTEAQQHLIRS 101

  Fly   295 LE--LLCPSTAVADAKNSSN----SLRISAELYKLLDALPRGIICLATSGVPDSLHEHARRRFVR 353
            |.  ||...:::....|:.|    :|.:|..:.|:      .|...:||.|...|:.|.:....:
Yeast   102 LAKVLLHQFSSINGKVNTVNEGQDNLFLSLFVKKI------SIEQQSTSHVSIKLNFHEKINLGQ 160

  Fly   354 EVTINMPSEGQRRQLVEHLCEVHELNISQ-TLLEHIARNTQGYVIADLTLLLRRVQQQLLTKDDF 417
            .:...:.||........|:..|.|..|.. ..||.......|.:   |:....::..:|...|.|
Yeast   161 HIDSILDSEETNESDTYHMGSVDEFIIYPFCCLEEQDELKNGSI---LSTEFDKIDLELDEDDGF 222

  Fly   418 DIEHIFLKSLSQTQPSASRSTDVRVSKMTAG-----------FEVIGGMEAL-------KRTLQV 464
            :.|     :|:....|.. :.|:.:||.|..           ||  |..|:|       :|....
Yeast   223 EGE-----TLNNCINSVG-NFDIPLSKQTLNLVNISYLPGTTFE--GQWESLYFGNNIKERLYSY 279

  Fly   465 SVLAGIRQSAAFARFG-------------LSLPKGVLLYGPPGCAKTTVAKCLAKEADM------ 510
            :.:     |...|||.             ::..|.:|::||||..|||:.|.|.::..:
Yeast   280 ATI-----SLKIARFKQTGDSNQEDITTLITNNKLLLVHGPPGTGKTTLCKALCQKLSVRREFSD 339

  Fly   511 -----------TFIATSAAEVYSPYVGCAERFISRIF---------DTARKNAPCLIFLDEIDSL 555
                       ..|..|.|.::|.:.|.:.:.||.:|         :..|....||: :||::::
Yeast   340 GSDTIDTNYKGIIIELSCARIFSKWFGESSKNISIVFKDIEELLKVNEGRGIFICLL-IDEVEAI 403

  Fly   556 VGRRTVSSGGGGGQVQLRILSTLLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLI 620
            ...||..|........:|:::||||:::.:   ....:.|.:|.:|..|.:|||.:  .|.|.:.
Yeast   404 ASSRTNLSSRNESTDGIRVVNTLLTQLDRL---KKYHNFLALATSNLLDSLDDAFV--DRADGVF 463

  Fly   621 HVPAPDEKSRLALLKLHSQRM 641
            :|..|..:..|.:||:..:.|
Yeast   464 YVGNPTAEGILHILKVCIEEM 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	108/476 (23%)
PCH2	NP_009745.2	P-loop containing Nucleoside Triphosphate Hydrolases	248..465	CDD:476819	51/229 (22%)