Protein Alignment CG12010 and afg2b

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001070056.2
• Gene: afg2b / 767648
• ZFINID: ZDB-GENE-060929-204
• Length: 748
• Species: Danio rerio
• Alignment Length: 782
• Identity: 251/782 - (32%)
• Similarity: 390/782 - (49%)
• Gaps: 142/782 - (18%)

  Fly    16 LDDSDLEPQRCYI-PAWENSTG------------------TGWYRCHLCDGSYAV---CWVTPRA 58
            :|..|::.|||.: ||..:|.|                  |.|.|..|.||...:   | |:|..
Zfish     9 VDAVDVDTQRCRMGPALMSSLGLRLGSPVLIRVLQGTCLCTAWPRRDLADGYLQISSQC-VSPDL 72

  Fly    59 GSETCCFLDGIVTSLTRFSPTNQRLVLLEPLKLVP--CVKRISCVITVTQELLQRPPVSLEDLKD 121
            ...|       :|:||           :.|.::.|  |:| ::||         :..|.::.|:.
Zfish    73 HKHT-------LTALT-----------VHPAQIKPLTCLK-LTCV---------KLKVFVQRLEH 109

  Fly   122 DVRIFLRHL-KLTKGCSVQHRRLVQLGIASVEIFDAPGVADDECFEI------AHDAELLLADIR 179
            ..|:..|.| :|..|..|....||.|.....||         .|..:      :..|.|:.|  |
Zfish   110 KKRVSERSLQELLDGIYVHEGHLVDLSGVKAEI---------RCVLVEKVNSGSQRAGLITA--R 163

  Fly   180 LGMPFSLDFIFKYLPHSFER----PMEQLEKLLETSK--ISFSHRFPTT-----------ALVVG 227
            ..:..|.....|:|....::    |:..:|.:..:.|  |:|..|:|.:           .|::|
Zfish   164 TCVDISTIQTVKHLDRQQQQVSAAPLGGMEDVFASLKEMITFPLRYPGSLRQLGLSCPRGLLLIG 228

  Fly   228 PVDCGKSGLLSEFLRRHSCNCFYITASQVLRSYPGETEEELRRIFQAAQTFKEKLRPLLPIVILI 292
            |...||:.|:....:........:...:|..|.|||:||.|||:|:.|:...:.    .|.|:||
Zfish   229 PPGVGKTLLVRCVAKDIGATLVTVNGPEVTGSRPGESEENLRRVFEQARDAADD----GPCVLLI 289

  Fly   293 EDLELLCPSTAVADAKNSSNSLRISAELYKLLDAL--PRGIICLATSGVPDSLHEHARR--RFVR 353
            ::::.|||...   ..:|:...|:.|:|..|:||:  ..|.:.:..:..||||....||  ||.|
Zfish   290 DEIDSLCPRRT---GSSSAPENRLVAQLLTLMDAIGSHEGFVIIGATNQPDSLDPALRRPGRFDR 351

  Fly   354 EVTINMPSEGQRRQLVEHLCEVHELNISQTL-LEHIARNTQGYVIADLTLLLRRV------QQQL 411
            ||.|.:||..|||.:::.:|  .|:.:|..: |..:|..|.|||.|||:.|.|..      ..|:
Zfish   352 EVIIGVPSLLQRRSILKCVC--REMPLSPDVDLNTLAEMTCGYVGADLSALSREAALQAMRHSQM 414

  Fly   412 LTKDDFDIEHIFLKSLSQTQPSASRSTDVRVSKMTAGFEVIGGMEALKRTLQVSVLAGIRQSAAF 476
            ...:...::| |:::|...|||..||:.........|:|.|||:|.:|..|:.|:...:|...||
Zfish   415 GASEPVSMQH-FMQALRHVQPSCLRSSIGATDFKPIGWEQIGGLEDVKLKLKQSIEWPMRFPEAF 478

  Fly   477 ARFGLSLPKGVLLYGPPGCAKTTVAKCLAKEADMTFIATSAAEVYSPYVGCAERFISRIFDTARK 541
            .|.|:|.|:||||||||||||||:.|..|..:..:|.:.|.||::|||||.:|:.::::|..||.
Zfish   479 VRLGVSRPRGVLLYGPPGCAKTTLVKAAASSSHCSFFSLSGAELFSPYVGDSEKTLAQLFAQARA 543

  Fly   542 NAPCLIFLDEIDSLVGRRTVSSGGGGGQVQLRILSTLLTEMNGI----------------VGGGS 590
            .||.::||||:||:||.|...| .....||.::||.||||::|:                :.||.
Zfish   544 CAPSIVFLDEVDSMVGSREDGS-SSSHSVQSQVLSVLLTELDGVGVRTLERRSTCRKIALLEGGD 607

  Fly   591 QQ---------------HILVVAATNRPDMIDDALLRPGRFDKLIHVPAPDEKSRLALLKLHSQR 640
            |:               .:|:|||||||:.:|.|||||||.|::|:||.||.::|||:|::.::.
Zfish   608 QEDVRLHQMELQEVCNKDVLIVAATNRPEALDSALLRPGRLDQIIYVPPPDLQARLAVLRICTKS 672

  Fly   641 MPFHENVFLQEIAARTDRYSGADLCNLCNEAAIEAFQRDFKATE-IELQDFEKVLTKQKSSLTQS 704
            :|.|::|.|:::||:|:.:|||||.|||.|||:.|.:.|..|.. :..:.|.|.|.....||:..
Zfish   673 VPLHQDVCLEDLAAQTELFSGADLENLCKEAALLALREDGLAVSCVRQKYFLKALQMLSPSLSAE 737

  Fly   705 QI 706
            |:
Zfish   738 QL 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	196/541 (36%)
afg2b	NP_001070056.2	CDC48	13..740	CDD:273521	250/778 (32%)