Protein Alignment CG12010 and Trip13

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_081458.1
• Gene: Trip13 / 69716
• MGIID: 1916966
• Length: 432
• Species: Mus musculus
• Alignment Length: 345
• Identity: 74/345 - (21%)
• Similarity: 140/345 - (40%)
• Gaps: 84/345 - (24%)

  Fly   388 IARNTQGYVIADLTLLLRRVQQQLLTKDDFDIE--------HIFLKSLSQTQPSASRSTDVRVSK 444
            ::||.|...|.|         .:|..||...|:        |||  .|::..|| |.:.|.....
Mouse    66 LSRNVQSVSIVD---------TELKAKDPQPIDLSACTIALHIF--QLNEEGPS-SENLDEETEN 118

  Fly   445 MTA-------GFEVIGGMEALKRTLQVS--VLAGIRQSAAFARFG-----LSLPKGVLLYGPPGC 495
            :.|       ..|..|..::|...::|.  :|..:..:..|:...     ::..:.|||:||||.
Mouse   119 IIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTVLFSDKNVDSNLITWNRVVLLHGPPGT 183

  Fly   496 AKTTVAKCLAKEADM---------TFIATSAAEVYSPYVGCAERFISRIFDTAR-----KNAPCL 546
            .||::.|.||::..:         ..|..::..::|.:...:.:.::::|...:     |.|...
Mouse   184 GKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVF 248

  Fly   547 IFLDEIDSLVGRRTVSSGGGGGQVQLRILSTLLTEMNGIVGGGSQQH--ILVVAATNRPDMIDDA 609
            :.:||::||...|.....|......:|:::.:||:::.|     ::|  ::::..:|..:.||.|
Mouse   249 VLIDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQI-----KRHSNVVILTTSNITEKIDVA 308

  Fly   610 LLRPGRFDKLIHVPAPDEKS--------------------RLALLKLHSQRM-PFHEN------V 647
            .:  .|.|...::..|...:                    |..||.|....| .|.||      :
Mouse   309 FV--DRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSL 371

  Fly   648 FLQEIAARTDRYSGADLCNL 667
            .|.||:.:::..||..|..|
Mouse   372 LLSEISRKSEGLSGRVLRKL 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	74/345 (21%)
Trip13	NP_081458.1	McrB	34..>205	CDD:441011	36/150 (24%)
		RecA-like_Pch2-like	121..319	CDD:410916	41/204 (20%)