Protein Alignment CG12010 and zgc:153738

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001073437.3
• Gene: zgc:153738 / 558115
• ZFINID: ZDB-GENE-061013-622
• Length: 818
• Species: Danio rerio
• Alignment Length: 815
• Identity: 154/815 - (18%)
• Similarity: 281/815 - (34%)
• Gaps: 260/815 - (31%)

  Fly    96 KRISCVITVTQELLQRPPVSLEDLKDDVRIF-------------LRHLKLTKGCSV--QHRRLVQ 145
            :.:||::  .|||.:.|   :...:|.|..|             .|||:.....||  |.||:::
Zfish    15 EELSCLL--PQELPEEP---IRPERDRVVFFQRIATFYVRYVQIFRHLEEAYDQSVHPQKRRVIR 74

  Fly   146 LGIASV--EIFDAPGVADDECFEIAHDAELLLADIRLGMPFSLDFIFKYLPHSFERPMEQLEKLL 208
            ..:.||  .:.:......::.|...|..:.::.|::| .|..|:.   .:|..|.|   :..|:|
Zfish    75 QVLDSVMGRVLELKNEMVEKEFSEYHYMDDVIQDLKL-TPEDLEI---PIPRYFIR---ERNKVL 132

  Fly   209 ETSKISFS----------------HRFPT---TALVVGPVDCGKSG-LLSEFLRR-H-------- 244
            :..:..|:                .|..|   |..|:...:..:.| |.::|:|. |
Zfish   133 QDRERMFAAILNQMDVMEKSGPPVMRMLTLERTIKVIQVAERARQGRLRAKFMREIHRDSERQKR 197

  Fly   245 ------SCNCFYITASQVLR---------------------------SYPGETE------EELRR 270
                  |.:...:...:|.|                           |||.:||      :.|||
Zfish   198 ADIETVSSDQAAVCIQKVWRGFMQRKITKRLREEEMIFLGMALDPKLSYPSQTELIAQNNKALRR 262

  Fly   271 IFQ-------------------------AAQTFKEKLR-------------PLLP--------IV 289
            ..|                         ..:|.|:::|             |..|        ::
Zfish   263 TRQEEHEDDYQKSIGSVVHQLREVEGSEMKETMKDQIRQWFIECRDATGSFPDYPEEEDGGSALI 327

  Fly   290 ILIEDLELLCPSTAVADAKNSSNS------LRISAELYKLLDALPR-GIICLATSGVPDSLHEH- 346
            ...:..|.|....|..:.::::.:      .:..|:..|:.|.... |:..|.::.:||....|
Zfish   328 FAEKTPEELAEELAAKEEEDANKNPKGKEDTKEKAKKGKIEDEEEEPGLKMLPSACLPDLERSHK 392

  Fly   347 ----------ARRRFVREVTINMPSEGQRRQL-VEHLCEVHELNISQTLLE---HIARNTQGYV- 396
                      ..:.|.:...:.:..|.:|::: ||...:|.|| :.|.|..   .:.:...|.|
Zfish   393 TYSEVWKNRNESKNFSQRHELELIKEDKRKEIEVEIRKQVDEL-MRQELANWKLAVDKEKSGKVK 456

  Fly   397 ---------------------IADLT---LLLRRVQQQLLTKDDFDIEHIFLKSLSQTQPSASRS 437
                                 .||.|   |....|:|:||.|.    |::.||
Zfish   457 GAAKKKKASKSAKRKKKDKDLTADRTTESLFEELVEQELLKKP----ENVKLK------------ 505

  Fly   438 TDVRVSKMTAGFEVIGGMEALKRTLQVS------VLAGIRQSAA-FARFGLS---------LPKG 486
                        :.:|....|..||:.|      .|:.:||..| :|...|.         |.|.
Zfish   506 ------------DYLGDYSYLGTTLRQSDIEPMPSLSDVRQVVALYAILPLGSQAVHEKSPLVKT 558

  Fly   487 VLLYGPPGCAKTTVAKCLAKEADMTFIATSAAEVYSPYVG--CAERFISRIFDTARKNAPCLIFL 549
            :||.||.|..|..:...:.:|........|...|...|.|  ..:..:..:|..||...|.:|::
Zfish   559 ILLVGPSGVGKKMLVHAICQETGANLFDLSPLNVAKKYPGRNGLQMMLHLVFKVARLMQPSVIWI 623

  Fly   550 DEIDSLVGRRTVSSGGGGGQVQL---RILSTLLTEMNGIVGGGSQQHILVVAATNRPDMID-DAL 610
            .:.:.:..|:....     :.:|   |:...|...:..|.|   :..:|:|..|:.|...| .:|
Zfish   624 GDAEKMFYRKVPKE-----EKELDPKRLKKDLPKILKSIRG---EDCVLIVGTTSDPHSADLKSL 680

  Fly   611 LRPGRFDKLIHVPAPDEKSRLALLK--LHSQRMPFHENVFLQEIAARTDRYSGADLC----NLCN 669
            .:  .::|:|.:|.||..||..:.|  :.........::.|..:|..:|.|:...:.    ::..
Zfish   681 CK--FYNKIILIPRPDYASRYVMWKELIKKNGGEVTGDLDLSSLAKISDGYTQGHMVQVVRSILT 743

  Fly   670 EAAIEAF-QRDFKATEI--ELQDFEKVLTKQKSSL 701
            |..|:.| :|...|:|.  .|...:.|..:::.:|
Zfish   744 ERRIQQFPKRPLTASEFVSPLARIDPVFQEEEEAL 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	122/658 (19%)
zgc:153738	NP_001073437.3	IQ	207..223	CDD:197470	2/15 (13%)
		RecA-like_IQCA1	531..690	CDD:410914	37/168 (22%)