Protein Alignment CG12010 and Pex1

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Alignment Length: 684
• Identity: 167/684 - (24%)
• Similarity: 301/684 - (44%)
• Gaps: 98/684 - (14%)

  Fly   106 QELLQRPPVSLEDLKDDVRIFLR---HLKLTKGC-------SVQHR---------------RLVQ 145
            :.::.||..::.:..:.:.:|..   |.|:.:..       ..||:               .||.
  Fly   330 ERVVLRPKTTVVNFVEKIELFANKKTHYKIMENAFKRFVIERTQHKPMLFNQEEVVRLEDDLLVT 394

  Fly   146 LGIASVE----IFDAPGVADDECFEIAHD-----AELLLADIRLGMPFSLDFIFKYLPHSFERPM 201
            :||....    :.||..:.:.:.:  |.|     .|::..:.....|.|:..:.: || .:::.:
  Fly   395 VGILPEHFRYCVVDAQFLKESKIY--AADLVRPVGEIIKEETPPTSPLSVQDLIQ-LP-EYDKIV 455

  Fly   202 EQLEKLLETS---KISFSHRFPTTALVVGPVDCGKSGLLSEFLRRHS-----CNCFYITASQVLR 258
            :|:.:.|..:   ....|.......|:.|....||:.|:...|.:.|     |:..:...|   |
  Fly   456 DQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGS---R 517

  Fly   259 SYPGETE---EELRRIFQAAQTFKEKLRPLLPIVILIEDLELLCPSTAVADAKNSSNSLRISAEL 320
            |...:||   ::||.||.:....       .|.::::|:|::|..:.....:::.....|::..:
  Fly   518 SKGRKTESIQKDLRNIFTSCLQH-------APAIVVLENLDVLAHAAGEQSSQDGEYYNRMADTV 575

  Fly   321 YKLL--DALPRGIICLATSGVPDSLHEH---ARRRFVREVTINMPS--EGQRRQLVEHLCEVHEL 378
            |:|:  ......|..:||.....:|::.   .|.|.|.:....:|:  ...|..::..||.  .:
  Fly   576 YQLIVQYTTNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADREIILRELCS--HI 638

  Fly   379 NISQTL-LEHIARNTQGYVIADLTLLLRRV---------QQQLLTKDDF--DIEHIFLKSLSQTQ 431
            |:::.| |...:..|:||...||...:.|.         .|.|||.|..  .:||.....|...|
  Fly   639 NVAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIESLEHTNSYCLQGIQ 703

  Fly   432 PSASRSTDVRVSKMTAGFEVIGGMEALKRTLQVSVLAGIRQSAAFARFGLSLPKGVLLYGPPGCA 496
            .:.....|...::|..  |.:.|:|::...|:..::...|....|....|....|||||||||..
  Fly   704 SNQRTGNDADANEMRV--EELPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQAGVLLYGPPGTG 766

  Fly   497 KTTVAKCLAKEADMTFIATSAAEVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSLVGRRTV 561
            ||.:...||...::..|:....|:.:.|:|.:|..:..:|:.||...||::|.||.|||..:|..
  Fly   767 KTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRGH 831

  Fly   562 SSGGGGGQVQLRILSTLLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLIHVPAPD 626
            .|.|    |..|:::.||||::|:.|   .|.:.|:|||:||:::|.||||.||.|:|:..|.||
  Fly   832 DSTG----VTDRVVNQLLTELDGVEG---LQGVTVIAATSRPELLDPALLRSGRIDRLVECPLPD 889

  Fly   627 EKSRLALLKLHSQRMPFHENVFLQEIAARTDRYSGADLCNLCNEA-------AIEAFQRDFKATE 684
            ..:|:.:.:..|..:...|.|.....|.:|..|:|||:.::...|       |:..|..:..|.:
  Fly   890 APARVRIFEALSSTLSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKEALAQFGHEKLAKK 954

  Fly   685 IELQDFEKVLTKQ--KSSLTQSQIDGYYKFAYRF 716
            |.|:....:.:.|  :.||:.|.:..|::...||
  Fly   955 ISLKQKHLIESFQTTRPSLSASDVAKYHRTYARF 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	142/528 (27%)
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	160/642 (25%)
		RecA-like_PEX1_r2	728..885	CDD:410934	60/163 (37%)