Protein Alignment CG12010 and CG14183

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Alignment Length: 623
• Identity: 114/623 - (18%)
• Similarity: 199/623 - (31%)
• Gaps: 225/623 - (36%)

  Fly   108 LLQ-RPPVSLEDLKDDVRIFLRHLKLTKGCSVQHRRLVQLGIASVEIFDAPGVADDECFEIAHDA 171
            ||| |.|..:||:.|.:|.:.:                       |.:||.|
  Fly   331 LLQFRSPWMMEDISDHIRAWFK-----------------------EFYDATG------------- 359

  Fly   172 ELLLADIRLGMPFSLDFIFKYLPHSFERPMEQLEKLLETSKISFSHRFPTTALVV-----GPVD- 230
                           :|      |.:..|::|                 .|.|||     .|::
  Fly   360 ---------------NF------HPYPDPVKQ-----------------GTVLVVIDETMTPMEF 386

  Fly   231 ---CGKSGLLSEFLRRHSCNCFYITASQVLRSYPGETEEELRRIFQAAQTFKEKLRPLLPIVILI 292
               .||..|....|::             ||.  .|.:|:.::        ||||:.|
  Fly   387 QESLGKKPLSKAELKK-------------LRD--KEKKEKRKK--------KEKLKQL------- 421

  Fly   293 EDLELLCPSTAVADAKNSSNSLRISAELYKLLDALPRGIICLATSGVPDSLHEHARRRFVREVTI 357
                      .:.:||...          ||.||           ||.|..:|....:.:..:..
  Fly   422 ----------KMKEAKRRK----------KLRDA-----------GVIDIGYELTASKAIENIEE 455

  Fly   358 NMPSEGQR-RQLVEHLCEVHELN---ISQTLLEHIARNTQG----YVIADLTLLLRRVQQQLLTK 414
            .|....:. |.:.|:|.:.|:..   :::..|..|.:..:|    |:..:..||     ::.|.|
  Fly   456 TMKKYSKDWRNVDEYLNKNHDPIKEWVTEEQLAKIHQEVRGLVDEYMRVEYELL-----REALAK 515

  Fly   415 D-----------------------------DFDIEHIF--LKSLSQTQPSASRSTDVRVSKMT-- 446
            |                             |..:|.::  ||.....:....|..|..::...
  Fly   516 DNDEKYKALKVKYPKKKKEKRKKKPKDMTGDRTLESLYNELKDAGIIEEIGHRDFDEFITDFNFV 580

  Fly   447 -------AGFEVIGGMEA-LKRTLQVSVLAGIRQSAAFARFGLSLPKGVLLYGPPGCAKTTVAKC 503
                   .|...:|..:. :|..:|.|:|       ....|.:..||.:||.||....|..:.:.
  Fly   581 ADDTRDEDGLTTLGPAKGDIKMVIQESML-------GMGEFDVPKPKSLLLIGPLNSGKRLLCEI 638

  Fly   504 LAKEADMTFIATSAAEVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSLVGRRTVSSGGGGG 568
            :|.|.|..|:..|....|. |....:.|:..|...|:...|.:::::|...|..::....   ..
  Fly   639 IASELDAVFMNLSPENTYK-YAKDLKYFLHVILKVAKAFQPTIMYIEEAHRLFWKKVPPE---AV 699

  Fly   569 QVQLRILST-----LLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLIHVPAPD-E 627
            ::..|:|.|     :|..:.      ....|::|..:|.|...:..:.|  .|.|::.:|..| .
  Fly   700 EINPRLLGTSLASKILKPLK------KNDKIVLVGTSNMPWAANGGIKR--AFQKVLLIPKCDYG 756

  Fly   628 KSRLALLKLHSQRMPFHENVFLQEIAART-DRYSGADL 664
            .|.|..|:|.::..|.....:.....||. ..|:..|:
  Fly   757 TSFLLWLELMTENAPDDMKEYAYSALARVLQAYNSGDI 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	97/510 (19%)
CG14183	NP_649172.3	Adgb_C_mid-like	<201..>278	CDD:412094
		globin helix H	201..232	CDD:412094
		IQCD	247..278	CDD:467745
		IQ motif	259..277	CDD:412094
		P-loop containing Nucleoside Triphosphate Hydrolases	617..750	CDD:476819	31/144 (22%)