Protein Alignment CG12010 and vcp

DIOPT Version :9

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_958889.1
• Gene: vcp / 327197
• ZFINID: ZDB-GENE-030131-5408
• Length: 806
• Species: Danio rerio
• Alignment Length: 570
• Identity: 182/570 - (31%)
• Similarity: 287/570 - (50%)
• Gaps: 79/570 - (13%)

  Fly   202 EQLEKLLETSKISFSH---------RFPTTALVVGPVDCGKSGLLSEFLRRHSCNCFYITASQVL 257
            :||.::.|..::...|         :.|...|:.||...||:.:............|.|...:::
Zfish   211 KQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIM 275

  Fly   258 RSYPGETEEELRRIFQAAQTFKEKLRPLLPIVILIEDLELLCPSTAVADAKNSSNSLRISAELYK 322
            ....||:|..||:.|:.|:       ...|.:|.|::|:.:.|.   .:..:.....||.::|..
Zfish   276 SKLAGESESNLRKAFEEAE-------KNAPAIIFIDELDAIAPK---REKTHGEVERRIVSQLLT 330

  Fly   323 LLDALPR--GIICLATSGVPDSLHEHARR--RFVREVTINMPSEGQRRQLVEHLCEVHELNI--- 380
            |:|.|.:  .:|.:|.:..|:|:....||  ||.|||.|.:|....|.:::    ::|..|:
Zfish   331 LMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEIL----QIHTKNMKLA 391

  Fly   381 SQTLLEHIARNTQGYVIADLTLLLRRVQQQLLTK--DDFDIE----------------HIFLKSL 427
            ....||.:|..|.|:|.|||..|......|.:.|  |..|:|                ..|..:|
Zfish   392 DDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWAL 456

  Fly   428 SQTQPSASRSTDVRVSKMTAGFEVIGGMEALKRTLQVSVLAGIRQSAAFARFGLSLPKGVLLYGP 492
            ||:.|||.|.|.|.|..:|  :|.|||::.:||.||..|...:.....|.:||::..||||.|||
Zfish   457 SQSNPSALRETVVEVPNIT--WEDIGGLDDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGP 519

  Fly   493 PGCAKTTVAKCLAKEADMTFIATSAAEVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSLVG 557
            |||.||.:||.:|.|....||:....|:.:.:.|.:|..:..|||.||:.|||::|.||:||:..
Zfish   520 PGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAK 584

  Fly   558 RRTVSSGGGGGQVQLRILSTLLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLIHV 622
            .|..:.|.|||... |:::.:||||:|:   .|::::.::.||||||:||.|:|||||.|:||::
Zfish   585 ARGGNVGDGGGAAD-RVINQILTEMDGM---SSKKNVFIIGATNRPDIIDPAILRPGRLDQLIYI 645

  Fly   623 PAPDEKSRLALLKLHSQRMPFHENVFLQEIAARTDRYSGADLCNLC------------------- 668
            |.||||||:|:||.:.::.|..::|.|..:|..|:.:|||||..:|
Zfish   646 PLPDEKSRIAILKANLRKSPISKDVDLDFLAKMTNGFSGADLTEICQRACKLAIRESIENEIRRE 710

  Fly   669 -----NEAAIEAFQRDFKATEIELQDFEKVLTKQKSSLTQSQIDGYYKFA 713
                 |.:|:|. :.|....||....||:.:...:.|::.:.|..|..||
Zfish   711 RERQTNPSAMEV-EEDDPVPEIRKDHFEEAMRFARRSVSDNDIRKYEMFA 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	SpoVK	201..707	CDD:223540	178/562 (32%)
		AAA	224..357	CDD:278434	36/136 (26%)
		AAA	487..623	CDD:278434	61/135 (45%)
vcp	NP_958889.1	CDC48	25..764	CDD:273521	182/570 (32%)
		CDC48_N	25..107	CDD:280513
		CDC48_2	131..191	CDD:215011
		AAA	241..370	CDD:278434	36/138 (26%)
		P-loop_NTPase	452..>534	CDD:304359	39/83 (47%)
		AAA	514..647	CDD:278434	61/136 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	708..727		4/19 (21%)
		Vps4_C	<718..760	CDD:286426	12/43 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	768..806

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D169540at33208
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820