Protein Alignment CG12010 and pex6

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_593468.1
• Gene: pex6 / 2542437
• PomBaseID: SPAC17A5.01
• Length: 948
• Species: Schizosaccharomyces pombe
• Alignment Length: 713
• Identity: 179/713 - (25%)
• Similarity: 321/713 - (45%)
• Gaps: 108/713 - (15%)

  Fly    68 GIVTSLT-RFSPT----NQRLVLLEPLKLVPCVKRISCVITVTQELLQRPPVSLEDLKDDVRIFL 127
            ||.:.:: |..||    :::|:....|.:|..||:  .|...::::...|..||....|.|.|
pombe   279 GIASRISLRTIPTQSCFSEKLLKAANLCVVQQVKQ--KVFLQSKQIFCVPINSLMANSDSVDI-- 339

  Fly   128 RHLKLTKGCSVQHRRLVQLGIASVEIFDAPGV-ADDECFEIAHDAEL---LLADIRLGMPFSLDF 188
              |:||:....    .:...:..::..:...: ..:|...|..|.:|   ||..:|..:   |:|
pombe   340 --LELTRNTDA----YIWYSVEEIDPLNTYNIYYTNEDTSIVLDTQLSHRLLPSLRKPL---LNF 395

  Fly   189 IFKYLPHSFERPMEQLEKLLETSKISFSHR----FPTTALVVGPVDCGKSGLLSEFLRRHSCNCF 249
            : |..|.|        :|||...:..|..:    |....|:.|....||:..:.|.....|...|
pombe   396 V-KVHPPS--------QKLLRFCRAFFDPQQVPGFNPFFLLHGNPFTGKTKAVEEVASLFSAPVF 451

  Fly   250 YITASQVLRSYPGETEEELRRIFQAAQTFKEKLRPLLPIVILIEDLELLCPSTAVADAKNSSNSL 314
            .|::.:...:.....|.:|       ..|.:.:......:|.::||::|..|:...:....|.|:
pombe   452 TISSYEFADATADHLEAKL-------DMFVQNVVKSPCAIIFVKDLDVLSISSDEGNIVPGSKSI 509

  Fly   315 RISAELYKLLDALPRG---II--CLATSGVPDSLHEHARRRFVREVTINMPSEGQRRQLVEHLCE 374
            :|......|:.: |:|   :|  |.:...:|   :|.....|. |:..:.....:|.:|:    :
pombe   510 QILLSKIDLVKS-PQGRYIVIGTCHSIEKIP---YEILSESFF-ELKFSELEMDERLELL----K 565

  Fly   375 VHELNI---SQTLLEHIARNTQGYVIADLTLL---LRRVQQQLLTKDDFDIEHIFLKSLSQTQPS 433
            ::..|:   .:..|:.:|..|......:|..|   :.:.....:.:..:|.:.|.|.....|:..
pombe   566 IYANNVIIDKRISLKDVALKTNSMSFGELECLPDHMTKAAVDRIKRTGYDNDSIILSGPIITEQD 630

  Fly   434 ASRSTD-VRVSKMTAGFEV-------IGGMEALKRTLQVSVLAGIRQSAAFARFGLSLPKGVLLY 490
            ...|.: :|..|....|.|       |||:|..|..|:.::...::....|:: ||....|||||
pombe   631 VDVSINRIRKEKSNTIFTVPKVNWDDIGGLEEAKTVLRDTLQLPLQFPELFSQ-GLKPRSGVLLY 694

  Fly   491 GPPGCAKTTVAKCLAKEADMTFIATSAAEVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSL 555
            ||||..||.:||.:|.|..:.|::....|:.:.|||.:|..:..:|:.||.::||:||.||:||:
pombe   695 GPPGTGKTLLAKAVATELSLEFVSIKGPELLNMYVGESEANVRNVFEKARNSSPCVIFFDELDSI 759

  Fly   556 VGRRTVSSGGGGGQVQLRILSTLLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLI 620
            ...|..||  ..|.|..|::|.||.|::.| ...:.:::.|:.||||||::|.:||||||||||:
pombe   760 APHRGNSS--DSGNVMDRVVSQLLAELDSI-SKDNNKYVFVIGATNRPDLLDPSLLRPGRFDKLV 821

  Fly   621 HVPA-PDEKSRLALLKLHSQRMPFHENVFLQEIAART-DRYSGADLCNLCNEAAIEAFQRDFKAT 683
            ::.. ..|:|:.::|:..::.....|.:.|.|||... ..::|||:..||::|.:.|.:|  |..
pombe   822 YLGINKSEESKASMLRALTKTFKLDETIDLNEIAKNCHPNFTGADMYALCSDAVLSAIKR--KTN 884

  Fly   684 EIEL------------------------------QDFEKVLTKQKSSLTQSQIDGYYKFAYRF 716
            ||:|                              :||...|.|.:.|:::.::..|....::|
pombe   885 EIDLLIQASGTDLSTEEFFKRNENQDSLELRITKEDFLTSLKKLRPSISEQELHRYEMVRHQF 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	141/543 (26%)
pex6	NP_593468.1	CDC48	<426..941	CDD:273521	140/536 (26%)