Protein Alignment CG12010 and Pex6

DIOPT Version :10

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_663463.1
• Gene: Pex6 / 224824
• MGIID: 2385054
• Length: 981
• Species: Mus musculus
• Alignment Length: 689
• Identity: 190/689 - (27%)
• Similarity: 307/689 - (44%)
• Gaps: 137/689 - (19%)

  Fly    98 ISCVITVTQ-ELLQRPPVSLEDLKDDVRIFLRHLKLTKGCSVQHRRLVQLGIASVEIFDAP-GVA 160
            :.||.|..| |:|:.   |||.|.....:|.: :|.|.|                   :|| |.|
Mouse   357 VLCVSTAGQVEILEG---SLERLPRWREMFFK-VKKTVG-------------------EAPEGPA 398

  Fly   161 DDECFEIAHDAELLLADIRLGMPFSLDFIFKYLPHSFERPMEQ-----LEKLL-ETSKISFSHRF 219
            .....:..| ..|.||...|....|       ||.....|.:.     ||.|: |...|...|..
Mouse   399 SAFLADTTH-TSLYLAGTALSHVPS-------LPSGRSPPWDSLSPPGLEALVNELCAILKPHLQ 455

  Fly   220 P--------TTALVVGPVDCGKSGLLSEFLRRHSCNCFYITASQVLRSYPGETEEELRRIFQAAQ 276
            |        :..|:.||...||:..::....|...:...:..|.:........|.:|:..|..|
Mouse   456 PGGTLLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRAVETKLQATFSRA- 519

  Fly   277 TFKEKLRPLLPIVILIEDLELLCPSTAVADAKNSSNSLRISAELYKLL---DALPR--GIICLAT 336
                  |...|.|:|:..::||     ..|........|::|.|..||   |||.|  .::.:||
Mouse   520 ------RRCRPAVLLLTAVDLL-----GRDRDGLGEDARVAATLRHLLLDEDALSRCPPLMVVAT 573

  Fly   337 SGVPDSLHEHARRRFVREVTINMPSEGQR----RQLVEHLCEVHELNISQTLLEHIARNTQGYVI 397
            :.....|....:..|..|:.:.:.||.||    :.|..||....|:|:.|     :||...|:|:
Mouse   574 TSRVQDLPTDVQTAFPHELEVPVLSEAQRLSILQALTAHLPLGQEVNLPQ-----LARRCAGFVV 633

  Fly   398 ADLTLLLRRVQQQLLTK-------------DDFD--------IEHIFLKSLSQTQPSASRSTDV- 440
            .||..||....:...|:             |:.|        :...|.::|.|.|.:.|::...
Mouse   634 GDLYALLTHTCRAACTRIRASGSAGGLSEEDEGDLCVAGFPLLAEDFGQALDQLQTAHSQAVGAP 698

  Fly   441 RVSKMTAGFEVIGGMEALKR----TLQVS------VLAGIRQSAAFARFGLSLPKGVLLYGPPGC 495
            |:..::  :..:||::.:|:    |:|:.      :..|:|:|            |:||:||||.
Mouse   699 RIPSVS--WHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRS------------GLLLHGPPGT 749

  Fly   496 AKTTVAKCLAKEADMTFIATSAAEVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSLVGRRT 560
            .||.:||.:|.|..:||::....|:.:.|||.:|..:..:|..||..|||:||.||:|||...|.
Mouse   750 GKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRG 814

  Fly   561 VSSGGGGGQVQLRILSTLLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLIHVPAP 625
            .|...||  |..|::|.||.|::|:   .|.|.:.|:.||||||::|.|||||||||||:.|.|.
Mouse   815 RSGDSGG--VMDRVVSQLLAELDGL---HSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGAS 874

  Fly   626 DEK-SRLALLKLHSQRMPFHENVFLQEIA-ARTDRYSGADLCNLCNEAAIEAFQRDFKATE--IE 686
            ::: |:|.:|...:::.....:|.|..:. ....:.:||||.:||::|.:.|.:|..:..|  :|
Mouse   875 EDRASQLRVLSAITRKFKLEASVSLANVLDCCPPQLTGADLYSLCSDAMMTALKRRVRDLEEGLE 939

  Fly   687 LQDFEKVLTKQ---------KSSLTQSQIDGYYKFAYRF 716
            |:....:||.:         :.|:::.::..|.:...:|
Mouse   940 LRSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKF 978

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	CDC48	<220..713	CDD:273521	156/554 (28%)
Pex6	NP_663463.1	CDC48	<467..978	CDD:273521	155/546 (28%)