Protein Alignment CG12010 and SPATA5

DIOPT Version :9

• Sequence 1: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_016863314.1
• Gene: SPATA5 / 166378
• HGNCID: 18119
• Length: 917
• Species: Homo sapiens
• Alignment Length: 589
• Identity: 182/589 - (30%)
• Similarity: 285/589 - (48%)
• Gaps: 79/589 - (13%)

  Fly   162 DECFEIAHDAELLLADIRLGMPFSLDFIFKYLPHSFERPMEQLEKLLETSKISFSHRFPTTALVV 226
            |..|::.:|           |...|....|.:....|.|::|.|...     |:....|...|:.
Human   345 DNQFKVTYD-----------MIGGLSSQLKAIREIIELPLKQPELFK-----SYGIPAPRGVLLY 393

  Fly   227 GPVDCGKSGLLSEFLRRHSCNCFYITASQVLRSYPGETEEELRRIFQAAQTFKEKLRPLLPIVIL 291
            ||...||:.:..............|...:::..:.||||.:||:|| |..|.:.      |.:|.
Human   394 GPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEAKLRQIF-AEATLRH------PSIIF 451

  Fly   292 IEDLELLCPSTAVADAKNSSNSLRISAELYKLLDAL----PRG-IICLATSGVPDSLHEHARR-- 349
            |::|:.|||..  ..|:|.... |:.|.|..|:|.:    ..| ::.|..:..|.:|....||
Human   452 IDELDALCPKR--EGAQNEVEK-RVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPG 513

  Fly   350 RFVREVTINMPSEGQRRQLVEHLCEVHELNISQTLLEHIARNTQGYVIADLTLL----------- 403
            ||.:|:.|.:|:...|..:::.|.......:::..|..:|.:..|||.|||.:|
Human   514 RFDKEIEIGVPNAQDRLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAAGTRILK 578

  Fly   404 ---------------------LRRVQQQLLTKDDFDIEHI-------FLKSLSQTQPSASRSTDV 440
                                 |||:.::.....|..:..:       ||::::..:|||.|  ::
Human   579 AHMYVSAFATGLTQTPQGLCALRRILKKQPNLPDVKVAGLVKITLKDFLQAMNDIRPSAMR--EI 641

  Fly   441 RVSKMTAGFEVIGGMEALKRTLQVSVLAGIRQSAAFARFGLSLPKGVLLYGPPGCAKTTVAKCLA 505
            .:......:..|||:|::|..|:.:|...::...:|.|.|:..||||||||||||:||.:||.||
Human   642 AIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIAKALA 706

  Fly   506 KEADMTFIATSAAEVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSLVGRRTVSSGGGGGQV 570
            .|:.:.|:|....|:.:.|||.:||.:...|..||..||.:||.||:|:|...|  .|..|.|.|
Human   707 NESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVER--GSSLGAGNV 769

  Fly   571 QLRILSTLLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLIHVPAPDEKSRLALLK 635
            ..|:|:.|||||:||   ...:.:.::|||||||.||.||:||||.|::|:||.||..:|..:.|
Human   770 ADRVLAQLLTEMDGI---EQLKDVTILAATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREIFK 831

  Fly   636 LHSQRMPFHENVFLQEIAARTDRYSGADLCNLCNEAAIEAFQRDFKATEIELQDFEKVLTKQKSS 700
            |....||....|.|.|:..:||.||||::..:|.|||:.|.:.|.:|..|..:.|.:.|:.....
Human   832 LQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAALLALEEDIQANLIMKRHFTQALSTVTPR 896

  Fly   701 LTQS 704
            :.:|
Human   897 IPES 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	SpoVK	201..707	CDD:223540	174/550 (32%)
		AAA	224..357	CDD:278434	39/139 (28%)
		AAA	487..623	CDD:278434	66/135 (49%)
SPATA5	XP_016863314.1	CDC48_N	65..133	CDD:389870
		CDC48	<323..913	CDD:273521	182/589 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D169540at33208
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820