DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12010 and spata5

DIOPT Version :9

Sequence 1:	NP_728878.1	Gene:	CG12010 / 38421	FlyBaseID:	FBgn0035443	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	XP_004911173.2	Gene:	spata5 / 100494828	XenbaseID:	XB-GENE-6054426	Length:	872	Species:	Xenopus tropicalis

Alignment Length:	567	Identity:	181/567 - (31%)
Similarity:	288/567 - (50%)	Gaps:	46/567 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 AHDAELLLADIRLGMPFSLDFIFKYLPHSFERPMEQLEKLLETSKISFSHRFPTTALVVGPVDCG 232
            |.:.:.|...:...|...|....|.:..:.|.|::|.|...     ::....|...|:.||...|
Frog   321 AKETDELKRKVTYNMIGGLKAELKEIRETIELPLKQPELFR-----NYGIPPPRGVLLYGPPGTG 380

  Fly   233 KSGLLSEFLRRHSCNCFYITASQVLRSYPGETEEELRRIFQAAQTFKEKLRPLLPIVILIEDLEL 297
            |:.:..........:...|...:::..:.||:|..||:||..|.       ...|.:|.|::|:.
Frog   381 KTLIARAIANEVGAHVTVINGPEIVSKFYGESEARLRQIFADAS-------QCCPSIIFIDELDA 438

  Fly   298 LCPSTAVADAKNSSNSLRISAELYKLLDAL----PRG-IICLATSGVPDSLHEHARR--RFVREV 355
            |||..  ..|:|.... |:.|.|..|:|.:    .:| ::.|..:..|.||....||  ||.:|:
Frog   439 LCPKR--EGAQNEVEK-RVVASLLTLMDGIGSEESQGQLLVLGATNRPHSLDPALRRPGRFDKEI 500

  Fly   356 TINMPSEGQRRQLVEHLCEVHELNISQTLLEHIARNTQGYVIADLTLL--------LRRVQQQLL 412
            .|.:|:...|..:::.:.:.....:.:..|..:|..|.|||.|||..|        |||..:.|.
Frog   501 EIGVPNAQGRLDILQKVLKKVPHRLKEEDLAQLADRTHGYVGADLAALCKEAGMNALRRTHRVLS 565

  Fly   413 TKDDFDIE-------HIFLKSLSQTQPSASRSTDVRVSKMTAGFEVIGGMEALKRTLQVSVLAGI 470
            ...|.::.       :.||::.::.:|||.|  :|.:......:..|||:|.:|..|:.:|...:
Frog   566 RPSDREMAGSVVITLNDFLQATNEVRPSAMR--EVAIDVPNVSWSDIGGLENVKLKLKQAVEWPL 628

  Fly   471 RQSAAFARFGLSLPKGVLLYGPPGCAKTTVAKCLAKEADMTFIATSAAEVYSPYVGCAERFISRI 535
            ....:|.|.|:..||||||||||||:||.:||.||.|:.:.|:|....|:.:.|||.:||.:..|
Frog   629 MHPDSFIRMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAVKGPELMNKYVGESERAVREI 693

  Fly   536 FDTARKNAPCLIFLDEIDSLVGRRTVSSGGGGGQVQLRILSTLLTEMNGIVGGGSQQHILVVAAT 600
            |..||..||.::|.||||:|    .:..|...|.|..|:|:.|||||:||   ...:.::::|||
Frog   694 FHKARAVAPSILFFDEIDAL----AIERGSSAGSVADRVLAQLLTEMDGI---EQLKDVVILAAT 751

  Fly   601 NRPDMIDDALLRPGRFDKLIHVPAPDEKSRLALLKLHSQRMPFHENVFLQEIAARTDRYSGADLC 665
            ||||:||.||:||||.|::|:||.||..:|..:.||....||....:.|:::..:|::||||::.
Frog   752 NRPDLIDKALMRPGRIDRIIYVPLPDAATRREIFKLRFHSMPISTEICLEKLVEQTEKYSGAEIT 816

  Fly   666 NLCNEAAIEAFQRDFKATEIELQDFEKVLTKQKSSLTQSQIDGYYKF 712
            .:|.|||:.|.:.|.:|..|..:.|||.|......:..|.|..|.::
Frog   817 AVCREAALLALEEDIQAEFIMGRHFEKALAIVTPRIPDSLIQFYERY 863

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12010	NP_728878.1	SpoVK	201..707	CDD:223540	172/527 (33%)
		AAA	224..357	CDD:278434	38/139 (27%)
		AAA	487..623	CDD:278434	65/135 (48%)
spata5	XP_004911173.2	CDC48	<309..868	CDD:273521	181/567 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D169540at33208
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920