Protein Alignment Ythdc1 and ythdc1

DIOPT Version :9

• Sequence 1: NP_647811.2
• Gene: Ythdc1 / 38420
• FlyBaseID: FBgn0027616
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_012815913.1
• Gene: ythdc1 / 493483
• XenbaseID: XB-GENE-1004178
• Length: 703
• Species: Xenopus tropicalis
• Alignment Length: 696
• Identity: 188/696 - (27%)
• Similarity: 275/696 - (39%)
• Gaps: 211/696 - (30%)

  Fly    29 EADIAEELQDFEFNTRSE-ASESNGGD----SSDSEPSISSVSTATSSLAGSSKRKTK------- 81
            ||:..|:.::.|.|...: .:|:...|    :.:||..::...        .||||::
 Frog     2 EAERGEQSKEGEVNVLDDILTEAPDQDDELYNPESEQDVNEKK--------GSKRKSERIEMTEN 58

  Fly    82 KPAKQSPQPAVETKSSKSSAKNK----AKREPTPE------------ELNGGKKKKRTDSGTKKT 130
            |..|||...:.:.....:|..||    .|.:|..|            ..:.|.::.|:.|||.:.
 Frog    59 KRQKQSSHMSRQPPQRVASGANKKVISTKGKPVTEYKCDDFHRQDRNRRSDGDRRIRSSSGTARD 123

  Fly   131 TSSEASDKV-----------KSKSPDTED----RQPSAKKSRTKIPSN----------------- 163
            ......||:           ||.:||...    .:.|.::||:...||
 Frog   124 NYKGPQDKISIRKRESDRRPKSSTPDMASEKIRHEVSRRQSRSSHSSNEGNSDDYGSERETGSSE 188

  Fly   164 ----------ANDSAGHKSDLSEAEDEKPSLPTLESDSESSDSDSGTQHKRNG------------ 206
                      .||..|.:.: .|.|||.......|.:.|..:.|...:.:|:|
 Frog   189 SSDEEQGNNSENDEEGMEEE-DEEEDEGEEAEEGEEEEEEYEQDEHARDQRDGNDYDTRSEASDS 252

  Fly   207 ---------GNGGGNGRGKPSS-------------------KSSTPEKDSVGGGTHSHSQ----- 238
                     |:...:|.|...|                   :|.:...||..|....|.:
 Frog   253 ESDSASFTDGDSVRSGSGSDISDQKKKERKRARGISPIVFDRSGSSASDSYAGSEKKHEKLPSSV 317

  Fly   239 --KGYDYMTKLNYLFRDTRFFLIKSNNSDNVQLSKNKSVWATLPQNDANLNQAFKEARNVLLIFS 301
              ...:...|:.|:.::.|||||||||.:||.|:|.|.||:|||.|:..||.||:.||:|:|:||
 Frog   318 RDVRKERTNKIRYILQEARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNAAFRSARSVILVFS 382

  Fly   302 VNESGKFAGFARMAAPSRRDIPQVAWVLPPSISPKALGGVIELDWICRKELSFNATLHLHNTWNE 366
            |.|||||.||||:::.|......:.||||..::.|.||||.::|||||:||.|...:||.|.|||
 Frog   383 VRESGKFQGFARLSSESHHGGSPIHWVLPAGMNAKMLGGVFKIDWICRRELPFTKCVHLTNPWNE 447

  Fly   367 GKPVKIGRDGQEIEPKIGGELCRLFPEDEQIELTPILKKSKETARVMREKGIHVIYKPPRSLS-- 429
            .||||||||||||||..|.:||.|||.|:.|:|..::.|.:...|         ::..|||..
 Frog   448 HKPVKIGRDGQEIEPDCGTQLCLLFPADDSIDLYQVIHKMRHKRR---------MHSQPRSRGRP 503

  Fly   430 SRGHGGGGRGGGRGSNHDHLGPMRHKRSYHGAPHHRPYRHHHGMGLPPGGGFKRSGSPYRQMGGA 494
            ||.......|..|...:|.....:.:..|....|.||             ||.:. ..|:::
 Frog   504 SRREATREVGRRRPEEYDIHNRKKPRIDYPPEFHQRP-------------GFVKD-PRYQEV--- 551

  Fly   495 AGAPPGGPGDMAMPSWER--YMSSAAAAEAYVADYMRNMHGQLPPLPF--VPPFAQLPIPGAGAG 555
                     |.......|  :::.:      ..||:|..|...||.|:  :||:..:
 Frog   552 ---------DRRFTGVRRDVFLNGS------YNDYVREFHNMGPPPPWQGMPPYPAM-------- 593

  Fly   556 AAGALPPGAAAAMYEQLPPPVRYYDGPGAPPLPDY----PPPQRPP 597
                          ||            ||..|.|    ||||..|
 Frog   594 --------------EQ------------APHHPYYQHHAPPPQAHP 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ythdc1	NP_647811.2	YTH	254..392	CDD:309322	82/137 (60%)
ythdc1	XP_012815913.1	YTH	335..472	CDD:367840	81/136 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	178	1.000	Domainoid score	I3516
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3506
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007281
OrthoInspector	1	1.000	-	-		oto105035
Panther	1	1.100	-	-	LDO	PTHR12357
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2345
SonicParanoid	1	1.000	-	-		X6164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090