Protein Alignment Ythdc1 and ythdc1

DIOPT Version :10

• Sequence 1: NP_647811.2
• Gene: Ythdc1 / 38420
• FlyBaseID: FBgn0027616
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001007411.1
• Gene: ythdc1 / 492769
• ZFINID: ZDB-GENE-041114-114
• Length: 679
• Species: Danio rerio
• Alignment Length: 667
• Identity: 193/667 - (28%)
• Similarity: 264/667 - (39%)
• Gaps: 166/667 - (24%)

  Fly    27 ENEADIAEEL------QDFE-FNTRSE--ASESNG-------GDSSDSEPSISS-------VSTA 68
            :.|.::.|::      ||.| :|..||  .:|..|       ||:.|::...:|       :..|
Zfish    10 DGELNVLEDILTDAPDQDDELYNPESEHDVNEKKGSKRKHDRGDAQDAKRLRASGHNTRQPMKRA 74

  Fly    69 TSSLAGSSKRKTKKP-AKQSPQPAVETKSSKSSAKNKAKREPTPEELNGGKKKKRTDSGTKKTTS 132
            ..| :||:.:||..| .:.:|:...:.:.:.|.....::.:.:......|....|......|...
Zfish    75 APS-SGSNGKKTSNPRGRHAPEDLYDDRKNHSGRGGASRADLSKGYGEKGLSSSRDSQRRIKPLM 138

  Fly   133 SEASDKVKSKSPDT------EDRQPSAKKSRTKIPSNANDSAGHKSDLSE-----AEDEKPSLPT 186
            .|.::|::..|.::      ..|:..|........|:...|.|:.||:.|     .|.|:.....
Zfish   139 PELTEKMRRTSEESAGRASRSSREEEAHSEEYATGSSVASSEGNCSDVEEEGAMPEEGEEKEGEE 203

  Fly   187 LESDSESSDSDSGTQHK-------RNGGNGGGNGRGKPSSKSSTPEKDSVGGGTHSHSQKG---- 240
            .|.:.|..|.|...:.:       ...||...:...:..:..|..|..|...|...||..|
Zfish   204 EEEEEEEGDDDDDEEEEYVLEEEDAREGNEQNDYDTRSEASDSRSESVSFSDGESVHSASGSDAS 268

  Fly   241 -----------------YDYMTKLNYLFRDTRFFLIKSNNSDNVQLSKNKSVWATLPQNDANLNQ 288
                             .|.:.||.::.|:.|||||||||.:||.|:|.|.||:|||.|:..||.
Zfish   269 GSEKKHEKLSSSVRDVRKDRINKLKHILREARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNA 333

  Fly   289 AFKEARNVLLIFSVNESGKFAGFARMAAPSRRDIPQVAWVLPPSISPKALGGVIELDWICRKELS 353
            ||:.||:|:|||||.|||||.||||:::.|......:.||||..::.|.||||.::|||||:||.
Zfish   334 AFRAARSVVLIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMNAKMLGGVFKIDWICRRELP 398

  Fly   354 FNATLHLHNTWNEGKPVKIGRDGQEIEPKIGGELCRLFPEDEQIELTPILKKSKETARVMREKGI 418
            |..|.||.|.|||.||||||||||||||:.|.|||.|||.||.|:|..::.|
Zfish   399 FTKTAHLANPWNEHKPVKIGRDGQEIEPECGTELCMLFPHDESIDLYQVIHK------------- 450

  Fly   419 HVIYKPPRSLSSRGHGGGGRGGGRGSNHDHLGPMRHKRSYHGAPHHRPYRHHHGMGLPPGGGFKR 483
                                             |||||..|..|..|. |..|...:|...|.:|
Zfish   451 ---------------------------------MRHKRRMHSEPRSRG-RLPHREPVPRDMGRRR 481

  Fly   484 SGS-----------------PYRQMGGAAGAPPGGPGDMAMPSWERYMSSA---AAAEAYVADYM 528
            ...                 |.|         ||...|...|..:|..|..   ........|||
Zfish   482 PEEYDMHNRKRPRIDYTPEFPQR---------PGFMQDPRNPPVDRRFSGVRRDVFLNGSYNDYM 537

  Fly   529 RNMHGQLPPLPFVPPFAQLPIPGAGAGAAGALPPGAAAAMYEQLPPPVRYYDGPGAPPLPDYPPP 593
            |..|..:.|.|  |.....|.||.                  :.||...||.  ..||    ||.
Zfish   538 REFHHNIGPPP--PWQGMAPYPGM------------------EHPPQHPYYQ--HHPP----PPQ 576

  Fly   594 QRPPPPGFDKAPSYEEF 610
            ..||..|....|....|
Zfish   577 AHPPYSGHHPMPHDARF 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ythdc1	NP_647811.2	YTH	255..391	CDD:410979	84/135 (62%)
ythdc1	NP_001007411.1	YTH	300..436	CDD:410979	84/135 (62%)