Protein Alignment Ythdc1 and ythdf2

DIOPT Version :9

• Sequence 1: NP_647811.2
• Gene: Ythdc1 / 38420
• FlyBaseID: FBgn0027616
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_005158820.1
• Gene: ythdf2 / 393220
• ZFINID: ZDB-GENE-040426-948
• Length: 613
• Species: Danio rerio
• Alignment Length: 502
• Identity: 118/502 - (23%)
• Similarity: 173/502 - (34%)
• Gaps: 139/502 - (27%)

  Fly     2 PRAARKQTLPMREMADLDAVHLGLDENEADIAEELQDFEFNTRSEASESNGGDSSDSEPSISSVS 66
            |.||.:.......|..||....||.....|:|.::         ..|...||       .:|.||
Zfish   170 PFAANEPLNKAVGMNSLDQGMAGLKIGAGDMAPKV---------VGSGLPGG-------PLSQVS 218

  Fly    67 TA-TSSLAGSSKRKT-------KKPAKQSPQPAVETKSSKSSAKNKAKREPTPEELNGGKKKKRT 123
            || |...|..:..||       .||||  |||.::||.....    ....|.|       .|...
Zfish   219 TAPTMPPASMAPAKTASWADIASKPAK--PQPKLKTKGGLGG----TNLPPPP-------IKHNM 270

  Fly   124 DSGT--------KKTTSSEASDKVKSKSPDTEDRQPSAKKSRTKIPSNANDSAG--HKSDLSEAE 178
            |.||        |.....:.|.....:.|:....||.|             :||  .:..||..:
Zfish   271 DIGTWDNKGNMPKPAAPQQTSLPTNGQPPNQSSPQPGA-------------TAGGVPQLPLSNGQ 322

  Fly   179 DEKPS-----------------LPTLESDSESSDSDSGTQ--HKRNGGNGGGNGRGKPSSKSSTP 224
            ...|:                 .|.|.....:|.....|:  ..||..||.|:..|.|   ..:|
Zfish   323 LVPPTGQLVQHPLPPGGQPGAVPPQLSQGPPASQPSQPTRWVPPRNRANGFGDAAGGP---GQSP 384

  Fly   225 EKDSVGGGT---------------HSHSQKGYDYMTKLNYLFRDTRFFLIKSNNSDNVQLSKNKS 274
            ....:||.|               ::::.|.:|:..|      ..|.|:|||.:.|::..|...:
Zfish   385 PNSGMGGITVPAEPHPVLEKLRMVNNYNPKDFDWNPK------HGRVFIIKSYSEDDIHRSIKYN 443

  Fly   275 VWATLPQNDANLNQAFKEARN---VLLIFSVNESGKFAGFARMAAPSRRDIPQVAWVLPPSISPK 336
            :|.:....:..|:.|::...|   :.|:||||.||.|.|.|.|.:|...:.....|      |..
Zfish   444 IWCSTEHGNKRLDAAYRSLANKGPLYLLFSVNGSGHFCGVAEMRSPVDYNTCAGVW------SQD 502

  Fly   337 ALGGVIELDWICRKELSFNATLHLHNTWNEGKPVKIGRDGQEIEPKIGGELCRLFPEDEQIELTP 401
            ...|..::.||..|::..:...|:....||.|||...||.||:            |.|:..::..
Zfish   503 KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEV------------PLDKARQVLK 555

  Fly   402 ILKKSKETARVMRE--------------KGIHVIYKPPRS-LSSRGH 433
            |:...|.|..:..:              |.:.|....|.| .|||.|
Zfish   556 IIASYKHTTSIFDDFSHYEKRQEEEESVKKVEVQGSDPYSNNSSRSH 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ythdc1	NP_647811.2	YTH	254..392	CDD:309322	39/140 (28%)
ythdf2	XP_005158820.1	Med15	<173..>411	CDD:312941	61/282 (22%)
		YTH	424..557	CDD:309322	41/150 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2345
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940