DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PHGPx and GPX6

DIOPT Version :9

Sequence 1:	NP_728869.1	Gene:	PHGPx / 38413	FlyBaseID:	FBgn0035438	Length:	238	Species:	Drosophila melanogaster
Sequence 2:	NP_192897.2	Gene:	GPX6 / 826765	AraportID:	AT4G11600	Length:	232	Species:	Arabidopsis thaliana

Alignment Length:	247	Identity:	107/247 - (43%)
Similarity:	141/247 - (57%)	Gaps:	40/247 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RQALRCYSMRRTPGPVLE-------------------LSRGQRQCLRLCTIMLPVSCAATPMNAI 56
            |.::|...:||| .|:|.                   |....|      .|.||:|.....:
plant     3 RSSIRLLYIRRT-SPLLRSLSSSSSSSSSKRFDSAKPLFNSHR------IISLPISTTGAKL--- 57

  Fly    57 SSAAQHSTAAAIDMSANGDYKNAASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNY 121
             |.::||.||:         ....|:|:|||||..||||.|..|||||:|:||:||:||||.:||
plant    58 -SRSEHSMAAS---------SEPKSLYDFTVKDAKGNDVDLSIYKGKVLLIVNVASQCGLTNSNY 112

  Fly   122 EKLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAMVCHLRDSKADIGEVFAKVDVNGDNAAPL 186
            .:|..|.|||...|..||.|||||||:|.|..:.|.:.......||:. .:|.|||||||.|||:
plant   113 TELAQLYEKYKGHGFEILAFPCNQFGNQEPGTNEEIVQFACTRFKAEY-PIFDKVDVNGDKAAPV 176

  Fly   187 YKYLKAKQTGTLGSGIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDIEKLL 238
            ||:||:.:.|..|.||||||.||||:|:|..::|:||||.|:.|.||::|||
plant   177 YKFLKSSKGGLFGDGIKWNFAKFLVDKDGNVVDRFAPTTSPLSIEKDVKKLL 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PHGPx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	85/152 (56%)
GPX6	NP_192897.2	Thioredoxin_like	66..229	CDD:294274	90/173 (52%)
GPX6	NP_192897.2	AhpC-TSA	75..210	CDD:278975	75/135 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	127	1.000	Domainoid score	I1748
eggNOG	1	0.900	-	-		E1_COG0386
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H133958
Inparanoid	1	1.050	186	1.000	Inparanoid score	I1405
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1483113at2759
OrthoFinder	1	1.000	-	-		FOG0000791
OrthoInspector	1	1.000	-	-		otm2424
orthoMCL	1	0.900	-	-		OOG6_100297
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X276
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.730