DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PHGPx and gpx3

DIOPT Version :9

Sequence 1:	NP_728869.1	Gene:	PHGPx / 38413	FlyBaseID:	FBgn0035438	Length:	238	Species:	Drosophila melanogaster
Sequence 2:	NP_001131027.1	Gene:	gpx3 / 798788	ZFINID:	ZDB-GENE-070222-3	Length:	222	Species:	Danio rerio

Alignment Length:	203	Identity:	66/203 - (32%)
Similarity:	96/203 - (47%)	Gaps:	31/203 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 AAQHSTAAAIDM----SANGDYKNAASIYEFTVKDTHGND-VSLEKYKGKVVLVVNIASKCGLTK 118
            |..|..||..:.    ||.||     |.:.:..|..:|.. :....|.||.|||||:|:..|||
Zfish    16 ALMHKIAALSNTQACNSAAGD-----SFHNYGAKTINGTQFIPFSHYAGKHVLVVNVATYUGLT- 74

  Fly   119 NNYEKLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAM--VCHLRDSKADIG--EVFAKVDVN 179
            ..|.:|..|.|:....|..||.|||:|||.|.|..:.|.:  :.::|.....:.  ::|.|.|||
Zfish    75 FQYVELNALHEELRHLGFTILGFPCDQFGKQEPGENNEILSALKYVRPGNGFVPNFQLFEKGDVN 139

  Fly   180 GDNAAPLYKYLK------AKQTGTLG----------SGIKWNFTKFLVNKEGVPINRYAPTTDPM 228
            ||....|:.:||      .:..|...          :.|||||.|||::.:|.|:.|:.|..:..
Zfish   140 GDGEQALFTFLKNACPPVGESFGATSNRLFWEPLKVNDIKWNFEKFLLDPDGRPVMRWFPRVNVS 204

  Fly   229 DIAKDIEK 236
            ::..||.|
Zfish   205 EVRADILK 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PHGPx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	55/173 (32%)
gpx3	NP_001131027.1	GSH_Peroxidase	37..210	CDD:238207	55/173 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1483113at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920