Protein Alignment Gtpx and Gpx4

DIOPT Version :10

• Sequence 1: NP_728869.1
• Gene: Gtpx / 38413
• FlyBaseID: FBgn0035438
• Length: 238
• Species: Drosophila melanogaster
• Sequence 2: NP_001034938.1
• Gene: Gpx4 / 29328
• RGDID: 69226
• Length: 253
• Species: Rattus norvegicus
• Alignment Length: 224
• Identity: 87/224 - (38%)
• Similarity: 129/224 - (57%)
• Gaps: 12/224 - (5%)

  Fly    18 SMRRTPGPVLELSRGQRQCLRLCTIMLPVSCAATPMNAISSAAQHSTA-AAIDMSAN-GDYKNAA 80
            |.|:.|||....:|.:|:.......|.|:.....|...:....|.|.: ..:.:.|: .|::.|.
  Rat    31 SPRKRPGPRRRRARARRRRRARPRRMEPIPEPFNPRPLLQDLPQTSNSHEFLGLCASRDDWRCAR 95

  Fly    81 SIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPCNQ 145
            |::||..||..|:.|.|:||:|.|.:|.|:||:.|.|..||.:|.||..:|.|.||.||.|||||
  Rat    96 SMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQ 160

  Fly   146 FGSQMPEADGEAMVCHLRDSKADIG---EVFAKVDVNGDNAAPLYKYLKA--KQTGTLGSGIKWN 205
            ||.|.|.::.|     :::..|...   ::::|:.||||:|.||:|::|.  |..|.||:.||||
  Rat   161 FGRQEPGSNQE-----IKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWN 220

  Fly   206 FTKFLVNKEGVPINRYAPTTDPMDIAKDI 234
            |||||::|.|..:.||.|..:|..|.||:
  Rat   221 FTKFLIDKNGCVVKRYGPMEEPQVIEKDL 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gtpx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	71/157 (45%)
Gpx4	NP_001034938.1	GSH_Peroxidase	96..249	CDD:238207	71/157 (45%)