Protein Alignment Gtpx and GPX5

DIOPT Version :10

• Sequence 1: NP_728869.1
• Gene: Gtpx / 38413
• FlyBaseID: FBgn0035438
• Length: 238
• Species: Drosophila melanogaster
• Sequence 2: NP_001500.1
• Gene: GPX5 / 2880
• HGNCID: 4557
• Length: 221
• Species: Homo sapiens
• Alignment Length: 186
• Identity: 63/186 - (33%)
• Similarity: 98/186 - (52%)
• Gaps: 25/186 - (13%)

  Fly    70 MSANGDYKNAASIYEFTVKDTHGND-VSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGE 133
            |..:.|.|  .:||::.....:.|: ||.::|.||.:|.||:|:.||||. .|.:|..|:|:...
Human    30 MDCHKDEK--GTIYDYEAIALNKNEYVSFKQYVGKHILFVNVATYCGLTA-QYPELNALQEELKP 91

  Fly   134 RGLVILNFPCNQFGSQMPEADGEAMVCHLRDSKADIG-----EVFAKVDVNGDNAAPLYKYLK-- 191
            .|||:|.|||||||.|.| .|.:.::..|:..:...|     ::|.|.||||:....::.:||
Human    92 YGLVVLGFPCNQFGKQEP-GDNKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHS 155

  Fly   192 ----AKQTGTLGS---------GIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDI 234
                ::..||..|         .|:|||.||||..:|:|:.|::.......:..||
Human   156 CPHPSEILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDI 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gtpx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	58/173 (34%)
GPX5	NP_001500.1	GSH_Peroxidase	39..211	CDD:238207	58/173 (34%)