Protein Alignment Gtpx and GPX2

DIOPT Version :10

• Sequence 1: NP_728869.1
• Gene: Gtpx / 38413
• FlyBaseID: FBgn0035438
• Length: 238
• Species: Drosophila melanogaster
• Sequence 2: NP_002074.2
• Gene: GPX2 / 2877
• HGNCID: 4554
• Length: 190
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 58/184 - (31%)
• Similarity: 89/184 - (48%)
• Gaps: 26/184 - (14%)

  Fly    79 AASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPC 143
            |.|.|:.:.....|..|....::|:.||:.|:||. |.|..::.:|.:|:.::..| ||:|.|||
Human     5 AKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRR-LVVLGFPC 68

  Fly   144 NQFGSQMPEADGEAMVCHLRDSKADIG-----EVFAKVDVNGDNAAPLYKYLKAK---------- 193
            ||||.| .....|.::..|:..:...|     .:..|.:|||.|..|::.|||.|
Human    69 NQFGHQ-ENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFS 132

  Fly   194 ---------QTGTLGSGIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDIEKLL 238
                     .:....|.:.|||.|||:..||.|..||:.|...::|..||::||
Human   133 LMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLL 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gtpx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	53/176 (30%)
GPX2	NP_002074.2	GSH_Peroxidase	7..182	CDD:238207	53/176 (30%)