Protein Alignment Gtpx and GPX1

DIOPT Version :10

• Sequence 1: NP_728869.1
• Gene: Gtpx / 38413
• FlyBaseID: FBgn0035438
• Length: 238
• Species: Drosophila melanogaster
• Sequence 2: NP_000572.2
• Gene: GPX1 / 2876
• HGNCID: 4553
• Length: 203
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 72/205 - (35%)
• Similarity: 104/205 - (50%)
• Gaps: 36/205 - (17%)

  Fly    59 AAQHSTAAAIDMSANGDYKNAASIYEFTVKDTHGND-VSLEKYKGKVVLVVNIASKCGLTKNNYE 122
            ||:.:.|||.          |.|:|.|:.:...|.: |||...:|||:|:.|:||..|.|..:|.
Human     3 AARLAAAAAA----------AQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYT 57

  Fly   123 KLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAMVCHLRDSKADIG-----EVFAKVDVNGDN 182
            ::.:|:.:.|.||||:|.|||||||.| ..|..|.::..|:..:...|     .:|.|.:|||..
Human    58 QMNELQRRLGPRGLVVLGFPCNQFGHQ-ENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAG 121

  Fly   183 AAPLYKYLK-----------AKQTG--------TLGSGIKWNFTKFLVNKEGVPINRYAPTTDPM 228
            |.||:.:|:           |..|.        ...:.:.|||.||||..:|||:.||:.....:
Human   122 AHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTI 186

  Fly   229 DIAKDIEKLL 238
            ||..|||.||
Human   187 DIEPDIEALL 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gtpx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	61/177 (34%)
GPX1	NP_000572.2	GSH_Peroxidase	15..192	CDD:238207	61/177 (34%)