DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PHGPx and gpx-6

DIOPT Version :9

Sequence 1:	NP_728869.1	Gene:	PHGPx / 38413	FlyBaseID:	FBgn0035438	Length:	238	Species:	Drosophila melanogaster
Sequence 2:	NP_001023368.1	Gene:	gpx-6 / 188313	WormBaseID:	WBGene00020373	Length:	188	Species:	Caenorhabditis elegans

Alignment Length:	158	Identity:	65/158 - (41%)
Similarity:	104/158 - (65%)	Gaps:	1/158 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 SIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPCNQ 145
            :||:|..|:..|..||:|||:.||||..|:||.||.|.:||....:|...|.|:|..:..|||||
Worm    30 TIYQFQAKNIDGKMVSMEKYRDKVVLFTNVASYCGYTDSNYNAFKELDGIYREKGFRVAAFPCNQ 94

  Fly   146 FGSQMPEADGEAMVCHLRDSKADIGEVFAKVDVNGDNAAPLYKYLKAKQTGTLGSGIKWNFTKFL 210
            |..|.||.:|: ::..::.|.....::::|::|||.|..||:|:||.::..:|.:.|.|||:|||
Worm    95 FEKQEPETEGK-ILDFVKSSYTYAPDMYSKIEVNGQNTHPLWKFLKKERGSSLSADIPWNFSKFL 158

  Fly   211 VNKEGVPINRYAPTTDPMDIAKDIEKLL 238
            |:|.|..:.||:.:.:|:|:.::|.:||
Worm   159 VDKNGHVVGRYSHSVNPIDLEEEISRLL 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PHGPx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	62/152 (41%)
gpx-6	NP_001023368.1	GSH_Peroxidase	30..182	CDD:238207	62/152 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48732
OrthoDB	1	1.010	-	-		D1483113at2759
OrthoFinder	1	1.000	-	-		FOG0000791
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100297
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16331
SonicParanoid	1	1.000	-	-		X276
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.860