DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PHGPx and gpx-7

DIOPT Version :9

Sequence 1:	NP_728869.1	Gene:	PHGPx / 38413	FlyBaseID:	FBgn0035438	Length:	238	Species:	Drosophila melanogaster
Sequence 2:	NP_001123171.1	Gene:	gpx-7 / 187542	WormBaseID:	WBGene00019846	Length:	197	Species:	Caenorhabditis elegans

Alignment Length:	177	Identity:	82/177 - (46%)
Similarity:	110/177 - (62%)	Gaps:	16/177 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 IDMSANGDYKNAASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYG 132
            ||||       ..:||:|:|:|..|:.|||:||.|.||::||:||.||||.:||::|..|.:||.
Worm    26 IDMS-------TGTIYDFSVRDNSGDLVSLDKYSGLVVIIVNVASYCGLTNSNYKELKSLNDKYH 83

  Fly   133 ERGLVILNFPCNQFGSQMP--EADGEAMVCHLRDSKADIGEVFAKVDVNG----DNAAPLYKYLK 191
            .|||.:..|||||||.|.|  |||....|......:.|:   :.||.|||    ....||:.:||
Worm    84 LRGLRVAAFPCNQFGFQEPHCEADINKFVNEKFSFEPDL---YGKVTVNGGPLIGEEEPLWTFLK 145

  Fly   192 AKQTGTLGSGIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDIEKLL 238
            .:|.|||...|||||||||||::|..:.|:.|:|:|....::|.|||
Worm   146 KEQGGTLFDAIKWNFTKFLVNRQGKVVARFGPSTNPKSFEEEIVKLL 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PHGPx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	74/158 (47%)
gpx-7	NP_001123171.1	GSH_Peroxidase	32..188	CDD:238207	74/158 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	110	1.000	Domainoid score	I3951
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I2852
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48732
OrthoDB	1	1.010	-	-		D1483113at2759
OrthoFinder	1	1.000	-	-		FOG0000791
OrthoInspector	1	1.000	-	-		mtm4796
orthoMCL	1	0.900	-	-		OOG6_100297
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X276
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.880